The role of medial prefrontal cortex in memory and decision making.
TLDR
It is proposed that the function of the medial prefrontal cortex is to learn associations between context, locations, events, and corresponding adaptive responses, particularly emotional responses, and that mPFC likely relies on the hippocampus to support rapid learning and memory consolidation.About:
This article is published in Neuron.The article was published on 2012-12-20 and is currently open access. It has received 1153 citations till now. The article focuses on the topics: Long-term memory & Memory consolidation.read more
Citations
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The Influences of Emotion on Learning and Memory.
TL;DR: A basic evolutionary approach to emotion is highlighted to understand the effects of emotion on learning and memory and the functional roles played by various brain regions and their mutual interactions in relation to emotional processing.
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Prefrontal-hippocampal interactions in episodic memory
TL;DR: These findings suggest a model of how the hippocampus and PFC, along with their intermediaries, operate as a system that uses the current context of experience to retrieve relevant memories.
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Neurobiology of Schemas and Schema-Mediated Memory.
TL;DR: The vmPFC and hippocampus may compete or synchronize to optimize schema-related learning depending on the specific operationalization of schema memory, which highlights the need for more precise definitions of memory schemas.
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Dorsal Anterior Cingulate Cortex: A Bottom-Up View
TL;DR: It is proposed that dACC neurons link contexts with strategies by integrating diverse task-relevant information to create a rich representation of task space and exert high-level and abstract control over decision and action.
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Childhood Adversity and Neural Development: A Systematic Review
TL;DR: Evidence for accelerated development in amygdala-mPFC circuits was limited but emerged in other metrics of neurodevelopment, and progress in charting neurodevelopmental consequences of adversity requires larger samples, longitudinal designs, and more precise assessments of adversity.
References
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An integrative theory of prefrontal cortex function
Earl K. Miller,Jonathan D. Cohen +1 more
TL;DR: It is proposed that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them, which provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task.
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Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory.
TL;DR: The account presented here suggests that memories are first stored via synaptic changes in the hippocampal system, that these changes support reinstatement of recent memories in the neocortex, that neocortical synapses change a little on each reinstatement, and that remote memory is based on accumulated neocorticals changes.
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Conflict monitoring and anterior cingulate cortex: an update
TL;DR: Recent research has begun to shed light on the larger function of the ACC, suggesting some new possibilities concerning how conflict monitoring might fit into the cingulate's overall role in cognition and action.
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The Role of the Medial Frontal Cortex in Cognitive Control.
TL;DR: New findings in cognitive neuroscience concerning cortical interactions that subserve the recruitment and implementation of cognitive control are evaluated, suggesting that monitoring-related pMFC activity serves as a signal that engages regulatory processes in the LPFC to implement performance adjustments.
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Reactivation of hippocampal ensemble memories during sleep.
TL;DR: In this paper, large ensembles of hippocampal "place cells" were recorded from three rats during spatial behavioral tasks and in slow-wave sleep preceding and following these behaviors, showing an increased tendency to fire together during subsequent sleep, in comparison to sleep episodes preceding the behavioral tasks.