Journal ArticleDOI
The test-negative design for estimating influenza vaccine effectiveness.
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TLDR
It is shown that test-negative studies of influenza VE can produce biased VE estimates if they include persons seeking care for ARI when influenza is not circulating or do not adjust for calendar time.About:
This article is published in Vaccine.The article was published on 2013-04-19. It has received 405 citations till now. The article focuses on the topics: Influenza vaccine & Vaccination.read more
Citations
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Journal ArticleDOI
Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants.
TL;DR: Efficacy of the BNT162b2 mRNA Vaccine in Qatar As of March 31, 2021, more than 265,000 people in Qatar had received both doses of the vaccine as mentioned in this paper.
Journal ArticleDOI
Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies
Edward A. Belongia,Melissa Simpson,Jennifer P. King,Maria E. Sundaram,Nicholas S. Kelley,Michael T. Osterholm,Huong Q. McLean +6 more
TL;DR: A systematic review and meta-analysis of Influenza vaccine effectiveness (VE) found vaccines provided substantial protection against H1N1pdm09, H1n1 (pre-2009), and type B, and reduced Protection against H3N2.
Posted ContentDOI
Waning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar
Hiam Chemaitelly,Hiam Chemaitelly,Patrick Tang,Mohammad Rubayet Hasan,Sawsan AlMukdad,Sawsan AlMukdad,Hadi M. Yassine,Hadi M. Yassine,Fatiha M. Benslimane,Fatiha M. Benslimane,Hebah A. Al Khatib,Hebah A. Al Khatib,Peter Coyle,Peter Coyle,Peter Coyle,Houssein H. Ayoub,Zaina Al Kanaani,Einas Al Kuwari,Andrew Jeremijenko,Anvar Hassan Kaleeckal,Ali Nizar Latif,Riyazuddin Mohammad Shaik,Hanan F. Abdul Rahim,Gheyath K. Nasrallah,Gheyath K. Nasrallah,Mohamed Ghaith Al Kuwari,Hamad Eid Al Romaihi,Adeel A. Butt,Adeel A. Butt,Mohamed H. Al-Thani,Abdullatif Al Khal,Roberto Bertollini,Laith J. Abu-Raddad +32 more
TL;DR: In this article, the authors investigated the persistence of BNT162b2 (Pfizer-BioNTech) vaccine effectiveness against infection and disease in Qatar, where the Beta and Delta variants have dominated incidence and PCR testing is done at a mass scale.
Journal ArticleDOI
Influenza Vaccine Effectiveness in the 2011–2012 Season: Protection Against Each Circulating Virus and the Effect of Prior Vaccination on Estimates
Suzanne E. Ohmit,Mark G. Thompson,Joshua G. Petrie,Swathi N. Thaker,Michael L. Jackson,Edward A. Belongia,Richard K. Zimmerman,Manjusha Gaglani,Lois Lamerato,Sarah Spencer,Lisa A. Jackson,Jennifer K. Meece,Mary Patricia Nowalk,Juhee Song,Marcus J. Zervos,Po Yung Cheng,Charles R. Rinaldo,Lydia Clipper,David K. Shay,Pedro A. Piedra,Arnold S. Monto +20 more
TL;DR: Vine effectiveness in the 2011-2012 season was modest overall, with lower effectiveness against the predominant A (H3N2) virus, which may be related to antigenic drift, but past history of vaccination might also play a role.
Journal ArticleDOI
Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings.
Mark G. Thompson,Edward Stenehjem,Shaun J. Grannis,Sarah Ball,Allison L. Naleway,Toan C. Ong,Malini B. DeSilva,Karthik Natarajan,Catherine H Bozio,Ned Lewis,Kristin Dascomb,Brian E. Dixon,Rebecca J. Birch,Stephanie A. Irving,Suchitra Rao,Elyse O. Kharbanda,Jungmi Han,Sue Reynolds,Kristin Goddard,Nancy Grisel,William F. Fadel,Matthew E Levy,Jill M. Ferdinands,Bruce Fireman,J.A Arndorfer,Nimish R. Valvi,Elizabeth A Rowley,Palak Patel,Ousseny Zerbo,Eric P. Griggs,Rachael M. Porter,Maria Demarco,Lenee Blanton,Andrea Steffens,Yan Zhuang,Natalie Olson,Michelle A. Barron,Pat Shifflett,Stephanie J. Schrag,Jennifer R. Verani,Alicia M Fry,Manjusha Gaglani,Eduardo Azziz-Baumgartner,Nicola P. Klein +43 more
TL;DR: In this article, the effectiveness of the Ad26.COV2.S vaccine against SARS-CoV-2 infection requiring hospitalization, ICU admission, or an emergency department or urgent care clinic visit was evaluated.
References
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Journal ArticleDOI
Estimability and estimation in case-referent studies
TL;DR: The concepts that case-referent studies provide for the estimation of "relative risk" only if the illness is "rare", and that the rates and risks themselves are inestimable, are overly superficial and restrictve.
Journal ArticleDOI
Immortal time bias in observational studies of drug effects
Samy Suissa,Samy Suissa +1 more
TL;DR: The bias from 20 cohort studies is described and illustrated by showing that unrelated drugs can be made to appear effective at treating cardiovascular disease (CVD) by way of immortal time bias.
Journal ArticleDOI
Evidence of bias in estimates of influenza vaccine effectiveness in seniors
TL;DR: The magnitude of the bias demonstrated by the associations before the influenza season was sufficient to account entirely for the associations observed during influenza season and indicates preferential receipt of vaccine by relatively healthy seniors.
Journal ArticleDOI
Influenza Vaccine Given to Pregnant Women Reduces Hospitalization Due to Influenza in Their Infants
TL;DR: The effectiveness of influenza vaccine given to mothers during pregnancy in preventing hospitalization among their infants, adjusted for potential confounders, was 91.5%, higher than the unadjusted effectiveness for infants aged <6 months.
Journal ArticleDOI
Pneumococcal disease after pneumococcal vaccination: an alternative method to estimate the efficacy of pneumococcal vaccine.
TL;DR: Trials of pneumococcal vaccine in healthy young adult populations suggest 75 to 95 per cent type-specific efficacy, but trials have not been done, however, in groups for which pneumococCal vac...
Related Papers (5)
The case test-negative design for studies of the effectiveness of influenza vaccine.
Influenza Vaccine Effectiveness in the 2011–2012 Season: Protection Against Each Circulating Virus and the Effect of Prior Vaccination on Estimates
Suzanne E. Ohmit,Mark G. Thompson,Joshua G. Petrie,Swathi N. Thaker,Michael L. Jackson,Edward A. Belongia,Richard K. Zimmerman,Manjusha Gaglani,Lois Lamerato,Sarah Spencer,Lisa A. Jackson,Jennifer K. Meece,Mary Patricia Nowalk,Juhee Song,Marcus J. Zervos,Po Yung Cheng,Charles R. Rinaldo,Lydia Clipper,David K. Shay,Pedro A. Piedra,Arnold S. Monto +20 more