scispace - formally typeset
Journal ArticleDOI

Tianeptina, un abordaje farmacológico atípico de la depresión

TLDR
The tianeptina, un farmaco atipico por su mecanismo de accion diferencial, contribuye a clarificar que in la fisiopatologia de la depresion hay algo mas que monoaminas as mentioned in this paper.
About
This article is published in Revista de Psiquiatría y Salud Mental.The article was published on 2019-07-01. It has received 12 citations till now.

read more

Citations
More filters
Journal ArticleDOI

Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes.

TL;DR: The latest research is summarized, focusing on changes in the plasticity of hippocampal neurons and glial cells in depression and the role of BDNF in the changes in hippocampal plasticity in depression, as well as caloric restriction and mitochondrial plasticity.
Journal ArticleDOI

Management of cognitive impairment in bipolar disorder: a systematic review of randomized controlled trials.

TL;DR: A systematic search was conducted on PubMed, PsycInfo, Cochrane, clinicaltrialsgov, and Embase databases for blinded or open-label randomized controlled trials evaluating the pro-cognitive effects of pharmacological, neurostimulation, or psychological interventions for bipolar disorder.
Journal ArticleDOI

Potencial abuso y dependencia de tianeptina. Revisión a propósito de un caso

TL;DR: In this article, el caso de un varon de 47 anos con diagnosticos de trastorno bipolar tipo ii, trastornos limite de personalidad and trastorón por uso sustancias, presentaba una dependencia a tianeptina, de la que llego a consumir 1.125mg al dia.
Journal ArticleDOI

How Antidepressant Drugs Affect the Antielectroshock Action of Antiseizure Drugs in Mice: A Critical Review.

TL;DR: In this article, a review of the interactions between antidepressants and antielectro-shock drugs was conducted in mice with maximal electroshock (MES) in a seizure model.
Journal ArticleDOI

Effects of Tianeptine Treatment on Depression and Cognitive Function in Patients with Alzheimer’s Disease: A 12-Month Retrospective Observational Study

TL;DR: In this article , Tianeptine and other antidepressants showed an antidepressant effect after 12 months with significant improvement on the Cornell Scale for Depression in Dementia, the Hamilton Depression Rating Scale, and the Neuropsychiatric Inventory-Depression subscale.
References
More filters
Journal ArticleDOI

The catecholamine hypothesis of affective disorders: a review of supporting evidence

TL;DR: The "catecholamine hypothesis of affective disorders" as discussed by the authors suggests that depression is associated with an absolute or relative decrease in catecholamines, particularly norepinephrine, available at central adrenergic receptor sites.
Journal ArticleDOI

A neurotrophic model for stress-related mood disorders.

TL;DR: Analysis of preclinical cellular and behavioral models of depression and antidepressant actions, as well as clinical neuroimaging and postmortem studies, are consistent with the hypothesis that decreased expression of BDNF and possibly other growth factors contributes to depression and that upregulation ofBDNF plays a role in the actions of antidepressant treatment.
Journal ArticleDOI

The corticosteroid receptor hypothesis of depression.

TL;DR: Mouse genetics, allowing for selective inactivation of genes relevant for HPA regulation and molecular pharmacology, dissecting the intracellular cascade of CR signaling, are the most promising future research fields, suited for identifying genes predisposing to depression.
Journal ArticleDOI

Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons.

TL;DR: It is raised the possibility that certain forms of chronic stress, by affecting specific neuronal elements in the amygdala, may lead to behavioral manifestations of enhanced emotionality, and stress-induced structural plasticity in amygdala neurons may provide a candidate cellular substrate for affective disorders triggered by chronic stress.
Journal ArticleDOI

Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction

TL;DR: Results show that LTP and CaMKII activity drive AMPA-Rs to synapses by a mechanism that requires the association between GluR1 and a PDZ domain protein.