Open AccessJournal Article
Topical NSAIDs for Chronic Musculoskeletal Pain in Adults.
Joseph R Yancey,Catherine Gill +1 more
TLDR
Evidence is lacking to determine the effectiveness of topical NSAIDs compared with oral NSAIDs, but diclofenac and ketoprofen are slightly more effective for relieving chronic pain associated with osteoarthritis in adults.Abstract:
Topical diclofenac and ketoprofen are slightly more effective than placebo for relieving chronic pain associated with osteoarthritis in adults. Evidence is lacking to determine the effectiveness of topical NSAIDs compared with oral NSAIDs.read more
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Journal ArticleDOI
An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
Olivier Bruyère,Germain Honvo,Nicola Veronese,Nigel K Arden,Jaime Branco,Elizabeth M Curtis,Nasser M. Al-Daghri,Gabriel Herrero-Beaumont,Johanne Martel-Pelletier,Jean-Pierre Pelletier,François Rannou,René Rizzoli,Roland Roth,Daniel Uebelhart,Cyrus Cooper,Jean-Yves Reginster +15 more
TL;DR: The updated ESCEO stepwise algorithm, developed by consensus from clinical experts in OA and informed by available evidence for the benefits and harms of various treatments, provides practical, current guidance that will enable clinicians to deliver patient-centric care in Oa practice.
Journal ArticleDOI
A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting.
Olivier Bruyère,Cyrus Cooper,Cyrus Cooper,Jean-Pierre Pelletier,Emmanuel Maheu,François Rannou,Jaime Branco,Maria Luisa Brandi,John A. Kanis,Roy D. Altman,Marc C. Hochberg,Johanne Martel-Pelletier,Jean-Yves Reginster +12 more
TL;DR: An updated assessment of the literature for selected interventions in OA, focusing on real-life data, is provided, with the aim of providing easy-to-follow advice on how to establish a treatment flow in patients with knee OA in primary care clinical practice.
Journal ArticleDOI
Hip Osteoarthritis: Etiopathogenesis and Implications for Management
TL;DR: It is proposed that shifting the focus of hip OA research and public health intervention to primary prevention and early detection may greatly improve the current management paradigm.
Journal ArticleDOI
Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies
Chao Zeng,Jie Wei,Monica S M Persson,Monica S M Persson,Aliya Sarmanova,Aliya Sarmanova,Michael Doherty,Michael Doherty,Dongxing Xie,Yilun Wang,Xiaoxiao Li,Jiatian Li,Huizhong Long,Guanghua Lei,Weiya Zhang,Weiya Zhang +15 more
TL;DR: Topical NSAIDs were effective and safe for OA and diclofenac patches may be the most effective topical NSAID for pain relief, but confirmation of the cardiovascular safety of topical NSAIDs still warrants further observational study.
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Alternative Medications for Medications in the Use of High-Risk Medications in the Elderly and Potentially Harmful Drug–Disease Interactions in the Elderly Quality Measures
TL;DR: A list of drug‐therapy alternatives to medications included in the two quality measures and some nonpharmacological resources will be useful to health professionals, consumers, payers, and health systems that care for older adults.