Journal ArticleDOI
Translational biotechnology for the control of ticks and tick-borne diseases
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In this paper, omics technologies have been applied to the study of the mechanisms involved in tick-host-pathogen interactions and the identification of candidate vaccine-protective antigens.About:
This article is published in Ticks and Tick-borne Diseases.The article was published on 2021-05-07. It has received 15 citations till now. The article focuses on the topics: Tick.read more
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Tick Saliva and Salivary Glands: What Do We Know So Far on Their Role in Arthropod Blood Feeding and Pathogen Transmission
TL;DR: Some of the known and emerging roles for arthropod components such as cement, salivary proteins, lipocalins, HSP70s, OATPs, and extracellular vesicles/exosomes in facilitating successful blood feeding from ticks are discussed and how tick-borne pathogens modulate(s) these components to infect the vertebrate host is discussed.
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Vaccinomics: a future avenue for vaccine development against emerging pathogens.
TL;DR: Vaccines are a major achievement in medical sciences, but the development of more effective vaccines against infectious diseases is essential for prevention and control of emerging pathogens worldw....
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One Health Approach to Identify Research Needs on Rhipicephalus microplus Ticks in the Americas
Agustín Estrada-Peña,A. R. Mallón,Sergio E. Bermúdez,José de la Fuente,Ana Domingos,Mario García,Marcelo Bahia Labruna,Octavio Merino,Juan Mosqueda,Santiago Nava,Rica Cruz,Matias P. J. Szabó,Evelina Luisa Tarragona,José M. Venzal +13 more
TL;DR: In this paper , a holistic view integrating an economically and ecologically sustainable control of infestations and transmitted pathogens by R. microplus in the Neotropics is presented, approaching its different facets of biology, ecology, distribution, and control.
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Frankenbacteriosis targeting interactions between pathogen and symbiont to control infection in the tick vector
Lorena Mazuecos,Pilar Alberdi,Angélica Hernández-Jarguín,Marinela Contreras,Margarita Villar,Alejandro Cabezas-Cruz,Ladislav Šimo,Almudena González-García,Sandra Díaz-Sánchez,Girish Neelakanta,Sarah Bonnet,Erol Fikrig,José de la Fuente +12 more
TL;DR: In this article , the results showed that Franken Sphingomonas producing A. phagocytophilum major surface protein 4 (MSP4) mimic pathogen and reduce infection in ticks by competition and interaction with cell receptor components of infection.
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The Impact of RNA Interference in Tick Research
TL;DR: RNAi will continue to lead to the discovery of an array of tick genes and molecules suitable for the development of vaccines and/or pharmacologic approaches for tick control and the prevention of pathogen transmission.
References
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Uber einen die Erzeugung und Verwandlung des Lichtes betreffenden heuristischen Gesichtspunkt
TL;DR: In el marco del Proyecto subvencionado by the Fundación Antorchas (FAN) as mentioned in this paper, el material was digitalizado, e.g., en la Biblioteca del Departamento de Fisica de la Facultad de Ciencias Exactas de la Universidad Nacional de La Plata.
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Commercialisation of a recombinant vaccine against Boophilus microplus.
TL;DR: The vaccine has been tested in the field, has been taken through the full registration process and is now in commercial use in Australia, and a related development has occurred in Cuba.
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A ten-year review of commercial vaccine performance for control of tick infestations on cattle.
José de la Fuente,Consuelo Almazán,Mario Canales,José M. Pérez de la Lastra,Katherine M. Kocan,Peter Willadsen +5 more
TL;DR: Commercial tick vaccines for cattle based on the Boophilus microplus Bm86 gut antigen have proven to be a feasible tick control method that offers a cost-effective, environmentally friendly alternative to the use of acaricides.
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Glycobiology of immune responses
TL;DR: The goal of this collection of expert reviews is to highlight what is known about how carbohydrates and their binding partners—the microbial, tumor, and host—cooperate within the immune system, while also identifying areas of opportunity to those willing to take up the challenge of understanding more about how carbohydrate influence immune responses.
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The Essential Role of Tick Salivary Glands and Saliva in Tick Feeding and Pathogen Transmission
TL;DR: During their long co-evolution with ticks and vertebrate hosts, microorganisms have indeed developed various strategies to exploit tick salivary molecules to ensure both acquisition by ticks and transmission, local infection and systemic dissemination within the vertebrate host.