Journal ArticleDOI
Treatment of pterygium.
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TLDR
In conclusion, excision and adjunctive treatment with mitomycin C or conjunctival autograft is the most acceptable and most popular mode of treating both primary and recurrent pterygium.Abstract:
The treatment of ocular pterygium has been subjected to the development and application of various new strategies in the last few years. The worrisome problem of recurrence seems to have been significantly reduced with the newer methods of treatment. The field is however, still evolving. This review sets out to examine the various newer approaches to treating pterygium and in spite of the recent developments, to highlight the remaining challenges thereby suggesting the possible direction of future research. Also, to suggest treatment options for Ophthalmologists working in environments with limited resources. A library search and Internet search of PubMed and Google was conducted in 2010. Search terms included "pterygium in combination with surgery", "radiotherapy", "chemotherapy", "graft", and "recurrence." Abstracts were reviewed and relevant articles especially those published from the year 2000 to date were given more attention and when possible, reviewed in full. The relevant references in such articles were also reviewed. In conclusion, excision and adjunctive treatment with mitomycin C or conjunctival autograft is the most acceptable and most popular mode of treating both primary and recurrent pterygium. Outcomes seem to have been further improved with adjuvant combination therapy and the introduction of newer approaches to treatment.read more
Citations
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Journal Article
Subconjunctival bevacizumab for primary pterygium excision; a randomized clinical trial.
TL;DR: Although the frequency of fibrovascular tissue crossing the limbus in the bevacizumab group was half that of the BSS group, the difference failed to reach a statistically significant level.
Journal ArticleDOI
Comparison of Two Techniques for the Treatment of Recurrent Pterygium: Amniotic Membrane vs Conjunctival Autograft Combined with Mitomycin C
Yasemin Arslan Katircioglu,Uğur Altiparmak,Seniz Engur Goktas,Burçin Köklü Çakir,Evin Singar,Firdevs Örnek +5 more
TL;DR: Amniotic membrane combined with MMC has similar recurrence rate to CA combined withMMC, in patients with recurrent pterygium, and similar outcomes and complication rates make AMT-MMC a promising method for the treatment of recurrent perygium cases.
Journal ArticleDOI
Regional conjunctivectomy with postoperative mitomycin C to treat chronic hyperemic conjunctiva.
TL;DR: In this paper, a new surgical technique to treat persistent irreversible hyperemic conjunctiva and evaluate the clinical results was introduced and a total of 571 patients with chronic conjunctival injection refractory to medical treatment were included.
Journal ArticleDOI
Low Recurrence Rate of Pterygium After Excision With Conjunctival Limbal Autograft: A Retrospective Study With Long-Term Follow-Up.
Jordan Masters,David J. Harris +1 more
TL;DR: This study highlights the safety and efficacy of CLAG in preventing the recurrence of primary and recurrent pterygium in patients performed by a single surgeon using the same technique between August 1989 and July 2013.
Journal ArticleDOI
Recurrence rate using fibrin glue-assisted ipsilateral conjunctival autograft in pterygium surgery: 2-year follow-up.
TL;DR: Fibrin glue-assisted ipsilateral conjunctival autograft seems to be safe and efficacious and associated with a low rate of recurrence in patients with primary pterygium excision.
References
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Journal ArticleDOI
Serious Complications of Topical Mitomycin-C after Pterygium Surgery
Roy S. Rubinfeld,Roy S. Rubinfeld,Roswell R. Pfister,Raymond M. Stein,C. Stephen Foster,Neil F. Martin,Neil F. Martin,Neil F. Martin,Samuel Stoleru,Samuel Stoleru,Audrey R. Talley,Mark G. Speaker +11 more
TL;DR: If mitomycin is used, the lowest possible concentration should be applied for the shortest time period in an effort to avoid these complications and the authors urge extreme caution in the use of this medication.
Journal ArticleDOI
Comparison of Conjunctival Autografts, Amniotic Membrane Grafts, and Primary Closure for Pterygium Excision
TL;DR: The relatively low recurrence rate for primary pterygia allows one to use amniotic membrane transplantation as an alternative first choice, especially for advanced cases with bilateral heads or those who might need glaucoma surgery later.
Journal ArticleDOI
Conjunctival autograft transplantation for advanced and recurrent pterygium
TL;DR: Free conjunctival grafts from the superotemporal bulbar conjunctiva of the same eye were used to resurface exposed sclera and extraocular muscle and, in all 14 patients with diplopia, extraocular movement was restored and the surgical approach is recommended as a safe and effective means of treating pterygia complicated by Conjunctival scarring withextraocular muscle involvement and requiring concurrent fornix reconstruction.
Journal ArticleDOI
Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases
TL;DR: The current knowledge on pterygium pathogenesis is summarised, highlighting recent developments and novel data is provided further demonstrating the complexity of this intriguing disease.
Journal ArticleDOI
The Treatment Of Pterygium
TL;DR: It will be important to develop a grading system, and surgeons will need to be conservative in the treatment of pterygium until such time as a single treatment provides a lower recurrence rate and complication rate.