Journal ArticleDOI
Treatment of pterygium.
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TLDR
In conclusion, excision and adjunctive treatment with mitomycin C or conjunctival autograft is the most acceptable and most popular mode of treating both primary and recurrent pterygium.Abstract:
The treatment of ocular pterygium has been subjected to the development and application of various new strategies in the last few years. The worrisome problem of recurrence seems to have been significantly reduced with the newer methods of treatment. The field is however, still evolving. This review sets out to examine the various newer approaches to treating pterygium and in spite of the recent developments, to highlight the remaining challenges thereby suggesting the possible direction of future research. Also, to suggest treatment options for Ophthalmologists working in environments with limited resources. A library search and Internet search of PubMed and Google was conducted in 2010. Search terms included "pterygium in combination with surgery", "radiotherapy", "chemotherapy", "graft", and "recurrence." Abstracts were reviewed and relevant articles especially those published from the year 2000 to date were given more attention and when possible, reviewed in full. The relevant references in such articles were also reviewed. In conclusion, excision and adjunctive treatment with mitomycin C or conjunctival autograft is the most acceptable and most popular mode of treating both primary and recurrent pterygium. Outcomes seem to have been further improved with adjuvant combination therapy and the introduction of newer approaches to treatment.read more
Citations
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Journal ArticleDOI
Clinical Results of the Use of Amniotic Membrane Transplantation Alone or in Combination with Adjuvant Therapies in Conjunctival Fornix Reconstruction
TL;DR: Amniotic membrane transplantation is a successful method when used alone in the reconstruction of early-stage conjunctival fornix obliteration and provides safe and effective results in advanced-stage fornIX obliteration when performed in combination with topical 0.04% MMC, oral mucosal transplantation, and limbal autograft surgeries.
Journal ArticleDOI
A Review of Mitomycin Use in Ophthalmic Surgery: Clarification of Safety Standards for Patients and Hospital Personnel
TL;DR: The aim of this article is to review the main indications for use of mitomycin in ophthalmology, the adverse effects after exposure, identify the mechanisms of accidental exposure toMitomycin by sanitary personnel and patients, and offer guidelines on safe handling of the drug.
Journal ArticleDOI
The Effect of Limbal Autograft in Recurrence of Pterygium
TL;DR: Limbal autografts shifting alone is not an appropriate treatment for primary pterygium because of the high recurrence rate.
Journal Article
Les Complications dans la Cure de Ptérygion avec Autogreffe Conjonctivale Fixe par Colle Biologique à Douala - Cameroun
TL;DR: Most complications in the surgical cure of pterygium with use of biological glue are resolutive under conservative treatment, and recurrence in unusual during the first six months after surgery.
References
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Journal ArticleDOI
Serious Complications of Topical Mitomycin-C after Pterygium Surgery
Roy S. Rubinfeld,Roy S. Rubinfeld,Roswell R. Pfister,Raymond M. Stein,C. Stephen Foster,Neil F. Martin,Neil F. Martin,Neil F. Martin,Samuel Stoleru,Samuel Stoleru,Audrey R. Talley,Mark G. Speaker +11 more
TL;DR: If mitomycin is used, the lowest possible concentration should be applied for the shortest time period in an effort to avoid these complications and the authors urge extreme caution in the use of this medication.
Journal ArticleDOI
Comparison of Conjunctival Autografts, Amniotic Membrane Grafts, and Primary Closure for Pterygium Excision
TL;DR: The relatively low recurrence rate for primary pterygia allows one to use amniotic membrane transplantation as an alternative first choice, especially for advanced cases with bilateral heads or those who might need glaucoma surgery later.
Journal ArticleDOI
Conjunctival autograft transplantation for advanced and recurrent pterygium
TL;DR: Free conjunctival grafts from the superotemporal bulbar conjunctiva of the same eye were used to resurface exposed sclera and extraocular muscle and, in all 14 patients with diplopia, extraocular movement was restored and the surgical approach is recommended as a safe and effective means of treating pterygia complicated by Conjunctival scarring withextraocular muscle involvement and requiring concurrent fornix reconstruction.
Journal ArticleDOI
Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases
TL;DR: The current knowledge on pterygium pathogenesis is summarised, highlighting recent developments and novel data is provided further demonstrating the complexity of this intriguing disease.
Journal ArticleDOI
The Treatment Of Pterygium
TL;DR: It will be important to develop a grading system, and surgeons will need to be conservative in the treatment of pterygium until such time as a single treatment provides a lower recurrence rate and complication rate.