Journal ArticleDOI
Trihalomethanes and maximum contaminant levels: the significance of inhalation and dermal exposures to chloroform in household water.
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TLDR
The literature yields a coherent and credible range of dose estimates, but the ratios of incremental lifetime cancer risk from inhalation of chloroform to risk from ingestion are much larger than the corresponding ratios for dose.About:Â
This article is published in Regulatory Toxicology and Pharmacology.The article was published on 1991-12-01. It has received 51 citations till now. The article focuses on the topics: Ingestion & Inhalation.read more
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Journal ArticleDOI
Chlorination disinfection byproducts in water and their association with adverse reproductive outcomes: a review
TL;DR: To identify the specific components that may be of aetiological concern and hence to fit the most appropriate exposure model with which to investigate human exposure to chlorinated DBPs, further detailed toxicological assessments of the mixture of byproducts commonly found in drinking water are also needed.
Journal ArticleDOI
Public Drinking Water Contamination and Birth Outcomes
Frank J. Bove,Mark C. Fulcomer,Judith B. Klotz,Jorge Esmart,Ellen M. Dufficy,Jonathan E. Savrin +5 more
TL;DR: The effects of public drinking water contamination on birth outcomes were evaluated in an area of northern New Jersey and it cannot resolve whether the drinking water contaminants caused the adverse birth outcomes; therefore, these findings should be followed up utilizing available drinkingWater contamination databases.
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Neural tube defects and drinking water disinfection by-products.
Judith B. Klotz,Laurie A. Pyrch +1 more
TL;DR: Sensitivity analyses restricted to isolated neural tube defect cases and mothers with known residence at conception yielded stronger associations, and other major groups of disinfection by-products showed little relation to these defects.
Journal ArticleDOI
Ingestion, inhalation, and dermal exposures to chloroform and trichloroethene from tap water.
Clifford P. Weisel,Wan-Kuen Jo +1 more
TL;DR: Time-series samples of expired alveolar breath were collected and analyzed to evaluate changes in concentrations of volatile organic compounds being expired, which reflects the rate of change in the bloodstream due to expiration, metabolism, and absorption into tissues.
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Multipathway risk assessment on disinfection by-products of drinking water in Hong Kong.
TL;DR: People living in Sai Kung have the highest risk of cancer due to the THM exposure through the multipathways, mainly because of the exposure to BDCM and dibromochloromethane (DBCM).
References
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Report of the Task Group on Reference Man
TL;DR: As this report of the task group on reference man, it will really give you the good idea to be successful.
Journal ArticleDOI
Human exposure to volatile organic compounds in household tap water: the indoor inhalation pathway
TL;DR: In this paper, a 3 compartiments utilisable for quantifier l'exposition des hommes aux composes volatiles organiques provenant du transfert de masse de l'eau de distribution vers l'air interieur.
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Routes of Chloroform Exposure and Body Burden from Showering with Chlorinated Tap Water
TL;DR: The mean internal dose due to dermal exposure was found to be approximately equal to that due to the inhalation exposure, and the effect of the showering activities on the concentration of chloroform shower air was examined.
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The role of skin absorption as a route of exposure for volatile organic compounds (vocs) in drinking water
H S Brown,D R Bishop,C A Rowan +2 more
TL;DR: It is concluded that skin absorption of contaminants in drinking water has been underestimated and that ingestion may not constitute the sole or even primary route of exposure.
Journal ArticleDOI
Chloroform exposure and the health risk associated with multiple uses of chlorinated tap water.
TL;DR: Since the estimates of chloroform risk from domestic water use for the three exposure routes--ingestion, inhalation, and dermal--are similar, all routes must be used to calculate the total risk when making policy decisions regarding the quality of the municipal water supply.
Related Papers (5)
Routes of Chloroform Exposure and Body Burden from Showering with Chlorinated Tap Water
Ingestion, inhalation, and dermal exposures to chloroform and trichloroethene from tap water.
Clifford P. Weisel,Wan-Kuen Jo +1 more