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Tumescent liposuction in lipoedema yields good long-term

TLDR
In this paper, Tumescent liposuction is a highly effective treatment for lipoedema with good morphological and functional long-term results, and the results showed a distinct reduction of subcutaneous fatty tissue (average 9846 mL per person) with improvement of shape and normalization of body proportions.
Abstract
Background Lipoedema is a painful disease in women with circumscribed increased subcutaneous fatty tissue, oedema, pain and bruising. Whereas conservative methods with combined decongestive therapy (manual lymphatic drainage, compression garments) have been well established over the past 50 years, surgical therapy with tumescent liposuction has only been used for about 10 years and long-term results are unknown. Objectives To determine the efficacy of liposuction concerning appearance (body shape) and associated complaints after a long-term period. Methods A total of 164 patients who had undergone conservative therapy over a period of years, were treated by liposuction under tumescent local anaesthesia with vibrating microcannulas. In a monocentric study, 112 could be re-evaluated with a standardized questionnaire after a mean of 3 years and 8 months (range 1 year and 1 month to 7 years and 4 months) following the initial surgery and a mean of 2 years and 11 months (8 months to 6 years and 10 months) following the last surgery. Results All patients showed a distinct reduction of subcutaneous fatty tissue (average 9846 mL per person) with improvement of shape and normalization of body proportions. Additionally, they reported either a marked improvement or a complete disappearance of spontaneous pain, sensitivity to pressure, oedema, bruising, restriction of movement and cosmetic impairment, resulting in a tremendous increase in quality of life; all these complaints were reduced significantly (P <0 AE001). Patients with lipoedema stage II and III showed better improvement compared with patients with stage I. Physical decongestive therapy could be either omitted (22AE4% of cases) or continued to a much lower degree. No serious complications (wound infection rate 1AE4%, bleeding rate 0AE3%) were observed following surgery. Conclusions Tumescent liposuction is a highly effective treatment for lipoedema with good morphological and functional long-term results.

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Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center

TL;DR: A comprehensive baseline needs to be established prior to surgery for a surgical treatment evaluation by means of patient-reported outcome measures as surgical intervention in lipedema patients is gaining traction and its effects should be well-documented.
Journal ArticleDOI

Lipedema prevalence and risk factors in Brazil

TL;DR: The estimated prevalence of lipedema in the population of Brazilian women is 12.3%, and anxiety, depression, hypertension, and anemia were also correlated with a high probability of the diagnosis.
Journal ArticleDOI

A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction

TL;DR: Liposuction reduces the severity of symptoms and the need for conservative treatment in lipedema patients, especially if it is performed in patients with a body mass index below 35 kg/m2 at an early stage of the disease.
Journal ArticleDOI

Lipedema Research—Quo Vadis?

TL;DR: In this paper , the authors focus on the clinical presentation of lipedema and provide the first clues towards the potential pathological mechanisms underlying its initiation and progression, despite all effort that has been undertaken to unravel the pathology of the disease, many questions have remained unanswered.
References
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Journal ArticleDOI

The tumescent technique. Anesthesia and modified liposuction technique.

TL;DR: Using the tumescent technique, liposuction can remove large volumes of fat with minimal blood loss and the slow infiltration of a local anesthetic solution of lidocaine and epinephrine minimizes the rate of systemic absorption and reduces the potential for toxicity.
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Lipedema of the legs: a syndrome characterized by fat legs and edema

TL;DR: There is little in the literature on abnormal localized depositions of body fat to clarify the syndrome of lipedema of the legs, but two of us (E. V. and E. A. H.) described it in 1940.
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Descriptive data analysis: a concept between confirmatory and exploratory data analysis.

TL;DR: This paper is proposed to fill the conceptual gap between CDA and EDA by “Descriptive Data Analysis” (“DDA”) which concept is mainly based on descriptive inferential statements.
Journal ArticleDOI

Lipedema: an inherited condition.

TL;DR: It is proposed that lipedema is a genetic condition with either X‐linked dominant inheritance or more likely, autosomal dominant inheritance with sex limitation, and appears to be a condition almost exclusively affecting females, presumably estrogen‐requiring as it usually manifests at puberty.
Journal ArticleDOI

Lipedema: a frequently misdiagnosed and misunderstood fatty deposition syndrome.

TL;DR: This continuing education activity is intended for physicians and nurses with an interest in skin and wound care to enhance the learner's competence in caring for patients with lipedema through understanding the differential diagnoses, pathophysiology, and treatment/management options.
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