Showing papers in "The Journal of Pain in 2006"

TL;DR: This is the first estimate of the prevalence and distribution of pain of predominantly neuropathic origin in the general population, using a previously validated and reliable data collection instrument.

TL;DR: It is shown that treatment elements that do not deliberately target cognitive factors can reduce pain catastrophizing and internal control of pain, and reduces the improvement of functioning in patients with chronic low back pain.

TL;DR: Clinical variables and severe acute pain were risk factors for chronic pain following breast cancer surgery, but psychosocial distress was not, which provides a basis for hypothesizing that aggressive management of acute postoperative pain may reduce chronic pain.

TL;DR: It is demonstrated that CPPs offer the most efficacious and cost-effective, evidence-based treatment for persons with chronic pain, relative to a host of widely used conventional medical treatment.

TL;DR: Experimental evidence suggests that opioid tolerance and opioid-induced hyperalgesia might limit the clinical utility of opioids in controlling chronic pain, but this study suggests that both conditions do occur within 1 month of initiating opioid therapy.

TL;DR: Membrane-stabilizing Na+ channel ligands suppress neuropathic pain by selectively reducing membrane resonance in injured afferents and hence ectopic hyperexcitability, a prime target for therapeutic intervention.

TL;DR: Changes in the expression of neuronal voltage-gated sodium channels may play a key role in the pathogenesis of both chronic neuropathic and chronic inflammatory pain conditions, and drugs that block these channels may have therapeutic efficacy with doses that are far below those that impair nerve impulse propagation or cardiovascular function.

TL;DR: The authors provide a comprehensive review of the relationships between marital functioning and chronic pain variables to advance future research and help treatment providers understand marital processes in chronic pain.

TL;DR: A decade-long increase in opioid prescribing by U.S. primary care physicians is described and important geographic-, racial/ethnic-, and insurance-related differences in who receives these medications are identified.

TL;DR: The results of the present study show that a higher qualityVR helmet was more effective at reducing pain than a lower quality VR helmet.

TL;DR: Demographic variables such as race and education should be considered together when evaluating the effectiveness of coping with pain, and the need for pain treatments that take into account the educational and cultural context of pain is suggested.

TL;DR: The validity and reliability of the DIRE Score are demonstrated and the score correlated well with measures of patient compliance and efficacy of long-term opioid therapy.

TL;DR: Pharmacologic studies showing the role of spinal voltage-sensitive calcium channels in neuropathic pain models provide evidence suggesting their applicability in human pain states.

TL;DR: It is demonstrated that persistent pain induces stress-like damaging modulatory effects in the hippocampus, which is one of the limbic regions involved in the pathophysiology of depression.

TL;DR: Oxytrex is the first large well controlled study to show strong analgesia with minimal withdrawal symptoms and better safety compared with oxycodone, and preclinical data also show a suppression of opioid tolerance and dependence.

TL;DR: The results support the validity of the PQAS items for assessing the effects of pain treatment on pain qualities of carpal tunnel syndrome.

TL;DR: The results suggest that the GCP Disability scale and 3 versions of the BPI Interference scale are reliable and valid measures of pain-related interference in persons with SCI and pain.

TL;DR: Catastrophizing and familial chronic pain history both were significantly associated with greater disability, with use of catastrophizing being the stronger predictor of disability.

TL;DR: The combination of research studies of human IBS patients and studies of rats with delayed rectal hypersensitivity after recovery from experimentally induced neonatal colitis strongly suggests a mechanism wherein both primary visceral hyperalgesia and secondary widespread cutaneous hyper algesia are dynamically maintained by tonic impulse input from the noninflamed colon and/or rectum.

TL;DR: In this article, the authors explored predictors of patient adjustment in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using a biopsychosocial template and selecting several pain-relevant constructs from physical, cognitive/behavioral, and environmental predictors.

TL;DR: Testosterone patch therapy at a dose of 7.5 mg/day normalizes hormone levels and appears to improve a number of quality of life parameters (eg, sexual function, well-being, mood) in men with OPIAD.

TL;DR: The results suggest that the activation of spinal cord astrocytes within 24 hours of incision contributes to mechanical hypersensitivity and might represent a novel target for the treatment of postoperative pain.

TL;DR: A dose-related DHEAS deficiency in a majority of nonhospitalized adults who are chronically consuming sustained-action oral or transdermal opioids for control of nonmalignant pain is documented.

TL;DR: In this article, the effects of subcutaneous injection of different formalin concentrations (5, 1, 2, 4, and 8%) were examined on the face-rubbing response.

TL;DR: Results from a survey demonstrate that breakthrough pain is highly prevalent and varied in opioid-treated patients with chronic noncancer pain, and will assist clinicians in assessing and managing this type of pain.

TL;DR: It is suggested that the anticipatory suppression of the alpha rhythms over the contralateral primary sensorimotor cortex predicts subsequent subjects' evaluation of pain intensity, in line with its crucial role for the discrimination of that intensity.

TL;DR: The notion that differences in pain perception between the sexes and among menstrual cycle phases are subtle is supported, and circulating gonadal hormones might mediate adaptation to cold pressor pain is suggested.

TL;DR: In this article, the authors study the experience of pain after placement of orthodontic elastic separators and the possible associations with the gingival crevicular fluid (GCF) composition changes at the level of interleukin 1-beta (IL-1β), substance P (SP), and prostaglandin-E 2 (PGE 2 ).

TL;DR: It is demonstrated that recalled pain is as valid as momentary data for many patients, and differences of momentary pain intensity ratings on an electronic visual analog scale (VAS) with weekly recalled pain on a 0 to 10 scale are compared.

TL;DR: The findings indicate that highly demanding attentional task performance and pain processing interfere as a result of difficulties in allocating attention.