Typing of Methicillin resistant Staphylococcus aureus: A technical review
PL Mehndiratta,Preena Bhalla +1 more
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TLDR
There is no consensus regarding the single best method for typing of MRSA strains and a need for harmonisation of typing techniques by following standard protocols is emphasised to establish surveillance networks and facilitate global MRSA control.About:
This article is published in Indian Journal of Medical Microbiology.The article was published on 2012-01-01 and is currently open access. It has received 72 citations till now. The article focuses on the topics: Phage typing & Typing.read more
Citations
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Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology
Sahreena Lakhundi,Kunyan Zhang +1 more
TL;DR: The origin of MRSA is described, with emphasis on the diverse nature of staphylococcal cassette chromosome mec (SCCmec).
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Fluoroquinolone Therapy in Staphylococcus aureus Infections: Where Do We Stand?
Neeta D Gade,Mohiuddin S. Qazi +1 more
TL;DR: Ciprofloxacin can no longer be used in empirical therapy against MRSA infections and use of other members of fluoroquinolone should be limited only to those strains that show laboratory confirmation of their susceptibility.
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Epidemiological and genetic diversity of Staphylococcus aureus causing bloodstream infection in Shanghai, 2009-2011.
Xu Chen,Wen-Kui Wang,Lizhong Han,Ying Liu,Hong Zhang,Jin Tang,Qingzhong Liu,Yu-chan Huangfu,Yuxing Ni +8 more
TL;DR: Investigating the epidemiological and genetic diversity of clinical S. aureus isolates from patients with bloodstream infection in four hospitals of Shanghai found healthcare-associated MRSA strains were still the main pathogen causing bloodstream infections in spite of the emergence of CA-MRSA strains in hospital setting.
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Molecular Typing of Methicillin Resistant Staphylococcus aureus Clinical Isolates on the Basis of Protein A and Coagulase Gene Polymorphisms.
TL;DR: It is revealed that testing for multiple gene polymorphisms is more useful for local epidemiologic purposes than traditional typing techniques for MRSA strains.
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Spa Typing of Staphylococcus aureus Strains Isolated From Clinical Specimens of Patients With Nosocomial Infections in Tehran, Iran.
TL;DR: A high methicillin-resistant S. aureus rate is reported in the authors' hospital and the need for continuous surveillance is emphasized to prevent the dissemination of multidrug resistance among different S.Aureus protein A types in Iran.
References
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Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.
Fred C. Tenover,Robert D. Arbeit,Richard V. Goering,P. A. Mickelsen,Barbara E Murray,D. H. Persing,B. Swaminathan +6 more
TL;DR: This research presents a novel, scalable and scalable approach that allows for real-time assessment of the severity of the infection and its impact on patients’ health.
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Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus.
Mark C. Enright,Nicholas P. J. Day,Catrin E. Davies,Sharon J Peacock,Sharon J Peacock,Brian G. Spratt +5 more
TL;DR: A multilocus sequence typing (MLST) scheme has been developed for Staphylococcus aureus and provides an unambiguous method for assigning MRSA and MSSA isolates to known clones or assigning them as novel clones via the Internet.
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The changing epidemiology of Staphylococcus aureus
TL;DR: Strains of methicillin-resistant Staphylococcus aureus, which had been largely confined to hospitals and long-term care facilities, are emerging in the community, and the prevalence of these strains in thecommunity seems likely to increase substantially.
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Multiplex PCR Strategy for Rapid Identification of Structural Types and Variants of the mec Element in Methicillin-Resistant Staphylococcus aureus
TL;DR: The development, validation, and application of a multiplex PCR strategy that allows quick presumptive characterization of the mec element types based on the structural features that were shown to be typical of mec elements carried by several MRSA clones are reported.
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Methicillin-Resistant Staphylococcus aureus
TL;DR: In the early 1940s the introduction of benzylpenicillin (Penicillin G) temporarily solved the problem of staphylococcal infections, but the continued use of this agent caused the selection of resistant strains, which produced penicillinase (β-lactamase).