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Understanding the Early Origins of the Education–Health Gradient A Framework That Can Also Be Applied to Analyze Gene–Environment Interactions

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TLDR
A framework for analyzing the causal effects of interventions in the presence of latent factors that could affect outcomes, even in the absence of interventions is developed, which will be useful in situations in which genes are included among the latent factors.
Abstract
In this article, we develop a framework for analyzing the causal effects of interventions in the presence of latent factors that could affect outcomes, even in the absence of interventions. This framework will be useful in situations in which genes are included among the latent factors. We estimate the model and study the early origins of observed later-life disparities by education. We determine the role played by cognitive, noncognitive, and early health endowments. We identify the causal effect of education on health and health-related behaviors. We show that family background characteristics and cognitive, noncognitive, and health endowments developed by age 10 are important determinants of health disparities at age 30. We also show that not properly accounting for personality traits results in overestimation of the importance of cognitive ability in determining later health. Selection on preexisting traits explains more than half of the observed differences in poor health and obesity. Education has an important causal effect in explaining differences in smoking rates. There are significant gender differences. We go beyond the current literature, which typically estimates mean effects, to compute distributions of treatment effects. We show that the effect of education on health varies among individuals who are similar in their observed characteristics, and how a mean effect can hide gains and losses for different individuals. This analysis highlights the crucial role played by promotion of good health at an early age and the importance of prevention in the reduction of health disparities. We speculate about how the model can be applied to genetic studies.

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References
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Journal ArticleDOI

Cluster analysis and display of genome-wide expression patterns

TL;DR: A system of cluster analysis for genome-wide expression data from DNA microarray hybridization is described that uses standard statistical algorithms to arrange genes according to similarity in pattern of gene expression, finding in the budding yeast Saccharomyces cerevisiae that clustering gene expression data groups together efficiently genes of known similar function.
Journal ArticleDOI

The Application of Electronic Computers to Factor Analysis

TL;DR: A survey of available computer programs for factor analytic computations and a analysis of the problems of the application of computers to factor analysis.
Journal ArticleDOI

Estimating causal effects of treatments in randomized and nonrandomized studies.

TL;DR: A discussion of matching, randomization, random sampling, and other methods of controlling extraneous variation is presented in this paper, where the objective is to specify the benefits of randomization in estimating causal effects of treatments.
Journal ArticleDOI

Closing the gap in a generation: health equity through action on the social determinants of health

TL;DR: The Commission on Social Determinants of Health (CSDH) as mentioned in this paper was created to marshal the evidence on what can be done to promote health equity and to foster a global movement to achieve it.
Book ChapterDOI

On the Concept of Health Capital and the Demand for Health

TL;DR: A model of the demand for the commodity "good health" is constructed and it is shown that the shadow price rises with age if the rate of depreciation on the stock of health rises over the life cycle and falls with education if more educated people are more efficient producers of health.
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