Journal ArticleDOI
Vaginal candidosis: epidemiological and etiological factors
Reads0
Chats0
TLDR
A review is presented of the emerging problem of candidal colonization regarding epidemiological and etiological factors and a significant increase in infections caused by non albicans species of candidas has been stated.About:
This article is published in International Journal of Gynecology & Obstetrics.The article was published on 2000-12-01. It has received 211 citations till now. The article focuses on the topics: Vaginal disease & Vaginitis.read more
Citations
More filters
Journal ArticleDOI
Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors
Bruna Gonçalves,Carina Sofia Vieira Ferreira,Carlos Alves,Mariana Henriques,Joana Azeredo,Sónia Carina Silva +5 more
TL;DR: Information about the current state of knowledge on the risk factors that predispose to VVC is provided, also including a revision of the epidemiology and microbiology of VVC, as well as of Candida virulence factors associated with vaginal pathogenicity.
Journal ArticleDOI
The use of mucoadhesive polymers in vaginal delivery
TL;DR: This review highlights the most important studies based on mucoadhesive polymer-systems like poly(acrylates), chitosan, cellulose derivatives, hyaluronic acid derivatives, pectin and traganth, starch, poly(ethylene glycol), sulfated polysaccharides, carrageenan, Na-alginate and gelatine.
Journal ArticleDOI
An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells
Anthony J. St. Leger,Jigar V. Desai,Rebecca A. Drummond,Abirami Kugadas,Fatimah Almaghrabi,Phyllis B. Silver,Kumarkrishna Raychaudhuri,Mihaela Gadjeva,Yoichiro Iwakura,Michail S. Lionakis,Rachel R. Caspi +10 more
TL;DR: A mouse model of ocular surface disease is used to reveal that commensals were present in the ocular mucosa and had functional immunological consequences, providing direct evidence that a resident commensal microbiome exists on the Ocular surface and identify the cellular mechanisms underlying its effects on ocular immune homeostasis and host defense.
Journal ArticleDOI
Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole.
TL;DR: Results of this study demonstrate that these new chitosan-TGA conjugates are very promising vehicles for the vaginal application of clotrimazole in treatment of mycotic infections.
Journal ArticleDOI
Improved treatment of vulvovaginal candidiasis with fluconazole plus probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14
Rafael Chacon Ruiz Martinez,Silvio Antonio Franceschini,Maristela Carbol Patta,Silvana Maria Quintana,Regina Celia Candido,Joseane Cristina Ferreira,E.C.P. De Martinis,Gregor Reid,Gregor Reid +8 more
TL;DR: To determine the ability of probiotic lactobacilli to improve the treatment of vulvovaginal candidiasis using a randomized, double‐blind and placebo‐controlled trial.
References
More filters
Journal ArticleDOI
Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans
TL;DR: This review summarizes all known clinical and experimental information about C. glabrata infections with comparisons to C. albicans as a means of contrasting the two species commonly observed and emphasizing the many recognized differences.
Interscience Conference on Antimicrobial Agents and Chemotherapy
Aki Okazaki,Matthew B Avison +1 more
Journal ArticleDOI
Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis.
TL;DR: Evidence is presented of an increasing incidence of vulvovaginal candidiasis, the cause of which is unclear, but this increase is probably the result of multiple factors including widespread abuse of antibiotics, possibly oral contraceptives, and most important inadequate vaginal therapy.
Journal ArticleDOI
Adherence of Candida albicans and other Candida species to mucosal epithelial cells.
R D King,J C Lee,A L Morris +2 more
TL;DR: The results suggest that there is a relationship between the adherence capabilities of the Candida species and their abilities to colonize mucosal surfaces, since those species which adhere are those which most frequently colonized mucosal surface.
Journal ArticleDOI
Immunopathogenesis of recurrent vulvovaginal candidiasis.
Paul L. Fidel,Jack D. Sobel +1 more
TL;DR: The results of both clinical studies and studies in an animal model of experimental vaginitis suggest that systemic CMI may not be the predominant host defense mechanism against C. albicans vaginal infections, and locally acquired mucosal immunity is under consideration as an important host defense at the vaginal mucosa.