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Open AccessJournal ArticleDOI

Validation of 4D dose calculation using an independent motion monitoring by the calypso tracking system and 3D polymer gel dosimetry

TLDR
An in-house developed 4D dose calculation algorithm that uses Calypso motion tracking data and to compare the results against 3D polymer gel dosimetry measurements shows good agreement with the gel-dosimetric measurements in most of the volume.
Abstract
This study aims to evaluate an in-house developed 4D dose calculation algorithm that uses Calypso motion tracking data and to compare the results against 3D polymer gel dosimetry measurements. For this, a cylindrical water phantom was constructed that allows to insert (i) the polymer gel, (ii) a PinPoint ® ionization chamber and (iii) Calypso beacons™ for motion tracking. A treatment plan covering a gel flask in the center of the static phantom plus a 1 mm margin homogeneously with dose was generated. During irradiation, however, the phantom was moved periodically by means of a robot with a peak-to-peak amplitude of 2.5 cm. The results of the 4D dose calculations show good agreement with the gel-dosimetric measurements in most of the volume. Remaining small deviations have to be evaluated in further experiments. The developed experimental setup allows for 3D-dosimetric validation of 4D dose calculations algorithms prior to application in patients.

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Citations
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Journal ArticleDOI

Absolute dosimetry with polymer gels-a TLD reference system.

TL;DR: This study presents a novel method combining 3D PG and TL dose measurements for the purpose of absolute 3D dose measurements that can also be applied in complex anthropomorphic phantoms using only a single measurement.
Journal ArticleDOI

4D in vivo dose verification for real-time tumor tracking treatments using EPID dosimetry.

TL;DR: Clinical feasibility and baseline accuracy are established of using the transmission EPID-based, in vivo patient dose verification for MLC-tracking treatments and a dynamic anthropomorphic phantom to verify baseline accuracy.
References
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Journal ArticleDOI

Polymer gel dosimetry

TL;DR: 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound, and clinical dosimetry applications of polymer gel Dosimetry are presented.
Journal ArticleDOI

The fundamental radiation properties of normoxic polymer gel dosimeters: a comparison between a methacrylic acid based gel and acrylamide based gels

TL;DR: This study reveals that the normoxic polymer gel dosimeter based on methacrylic acid (nMAG) studied in this work has inferior radiation properties as compared to the polyacrylamide gelatine (PAG) gel dosimeters.
Journal ArticleDOI

Investigation of the PAGAT polymer gel dosimeter using magnetic resonance imaging

TL;DR: It is shown that the normoxic PAGAT polymer gel has the properties of a dosimetric tool, which can be used in clinical radiotherapy, while offering the significant advantage of simplification of the manufacturing procedure.
Journal ArticleDOI

The application of the sinusoidal model to lung cancer patient respiratory motion.

TL;DR: This study demonstrates that the pdfs of mean position (z0), amplitude of motion (b), and period (tau) can be used for sampling to obtain more realistic respiratory traces.
Journal ArticleDOI

Computer systems and mechanical tools for stereotactically guided conformation therapy with linear accelerators.

TL;DR: All system components are aimed at conforming dose distributions for fractionated radiotherapy treatments to the target to improve sparing of adjacent normal tissues, and at achieving a sufficient geometrical accuracy in the dose application.
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