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Validation of a patient-specific hemodynamic computational model for surgical planning of vascular access in hemodialysis patients

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TLDR
A patient-specific computational vascular network model that includes vessel wall remodeling to predict blood flow change within 6 weeks after surgery for different arteriovenous fistula configurations is reviewed, potentially reducing the incidence of vascular access dysfunctions and the need of patient hospitalization.
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This article is published in Kidney International.The article was published on 2013-12-01 and is currently open access. It has received 70 citations till now. The article focuses on the topics: Arteriovenous fistula & Hemodynamics.

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Big Data, Big Knowledge: Big Data for Personalized Healthcare

TL;DR: It is proposed in this position paper that big data analytics can be successfully combined with VPH technologies to produce robust and effective in silico medicine solutions.
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Arteriovenous Fistula Development in the First 6 Weeks after Creation

TL;DR: Two-week measurements at 2 weeks may be of value in the early identification of fistulas that are unlikely to develop optimally in a multicenter hemodialysis fistula maturation study.
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Computational neurobiology is a useful tool in translational neurology: the example of ataxia

TL;DR: This inquiry lays a foundation for using computation to understand neurobiochemical and electrophysiological pathophysiology of spinocerebellar ataxias and may contribute to development of therapeutics.
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Novel Paradigms for Dialysis Vascular Access: Upstream Hemodynamics and Vascular Remodeling in Dialysis Access Stenosis

TL;DR: The role of the disturbed flow condition in acting as upstream event in the pathogenesis of venous intimal hyperplasia and in producing subsequent local vascular remodeling in autogenous arteriovenous fistulae used for hemodialysis access is discussed.
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Transitional Flow in the Venous Side of Patient-Specific Arteriovenous Fistulae for Hemodialysis

TL;DR: This study reconstructed realistic geometrical models of four AVFs from magnetic resonance images acquired in a previous clinical study and observed transitional laminar to turbulent-like flow developing in the juxta-anastomotic vein and damping towards the venous outflow, but not in the proximal artery.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Increasing arteriovenous fistulas in hemodialysis patients: Problems and solutions

TL;DR: Implementing these measures is likely to increase the prevalence of fistulas in any given dialysis unit, however, differences among dialysis units are likely to persist because of differences in gender, race, and co-morbidity mix of the patient population.
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EBPG on Vascular Access

TL;DR: Department of Surgery, University Hospital Maastricht, The Netherlands, Nephrology, Dialysis and Intensive Care Unit; Lapeyronie University Hospital, Montpellier, France, Department of Diagnostic and Interventional Radiology, Helios Klinikum Wuppertal, University hospital Witten/Herdecke, Germany.
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Validation of a one-dimensional model of the systemic arterial tree.

TL;DR: This study constitutes a first validation of the complete one-dimensional model using human pressure and flow data and supports the applicability of the 1-D model in the human circulation.
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ESRD patients in 2004: global overview of patient numbers, treatment modalities and associated trends.

TL;DR: An alternative approach to reporting international ESRD-relevant data is pursued in the Dialysis Outcomes and Practice Patterns Study (DOPPS), and an extract of the latter is supplied for use and reference by renal care specialists and healthcare administrative bodies.
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