Journal ArticleDOI
Vernoguinamide: A new ceramide and other compounds from the root of Vernonia guineensis Benth. and their chemophenetic significance
Steven Collins Njonte Wouamba,Gervais Mouthé Happi,Gervais Mouthé Happi,Bruno Ndjakou Lenta,Norbert Sewald,Simeon F. Kouam +5 more
TLDR
The chemical investigation of the roots of Vernonia guineensis Benth resulted in the isolation of a new ceramide, named vernoguinamide, together with fifteen known compounds, and compounds 6, 7 and 14–16 were extracted for the first time from the species.About:
This article is published in Biochemical Systematics and Ecology.The article was published on 2020-02-01. It has received 12 citations till now. The article focuses on the topics: Triterpene & Stigmasterol.read more
Citations
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Journal ArticleDOI
Antibacterial Flavonoids and Other Compounds from the Aerial Parts of Vernonia guineensis Benth. (Asteraceae).
Steven Collins Njonte Wouamba,Gervais Mouthé Happi,Gervais Mouthé Happi,Gervais Mouthé Happi,Michel Nguiam Pouofo,Joseph Tchamgoue,Jean-Bosco Jouda,Frida Longo,Bruno Ndjakou Lenta,Norbert Sewald,Simeon F. Kouam +10 more
TL;DR: Eleven compounds are reported herein for the first time from this species on the basis of extensive spectroscopic analyses, particularly 1D and 2D NMR, and HR‐ESI‐MS and by comparison of their data with those reported in the literature.
Journal ArticleDOI
Bio-guided isolation of anti-leishmanial natural products from Diospyros gracilescens L. (Ebenaceae)
Cyrille Armel N. Njanpa,Steven Collins Njonte Wouamba,Lauve Rachel Tchokouaha Yamthe,Darline Dize,Brice Mariscal T. Tchatat,Patrick Valère F. Tsouh,Michel Nguiam Pouofo,Jean-Bosco Jouda,Bruno Lenta Ndjakou,Norbert Sewald,Simeon F. Kouam,Fabrice Fekam Boyom +11 more
TL;DR: The results obtained indicated that the hydroethanolic extract from the D. gracilescens trunk and the derived hexane fraction have very potent inhibitory effect on cultivated promastigotes and amastigote forms of L. donovani parasite.
Journal ArticleDOI
A new cerebroside and bioactive compounds from Celtis adolphi-friderici Engl. (Cannabaceae)
Kevine Johane Dongmo Jumeta,Donald Ulrich Kenou Kagho,Joël E. T. Ateba,Yannick Stéphane Fongang Fotsing,Jean Jules Kezetas Bankeu,Norbert Sewald,Bruno Lenta Ndjakou,Lateef Mehreen,Muhammad Ali,Augustin S. Ngouela +9 more
TL;DR: In this paper, a phytochemical investigation of the roots of Celtis adolphi-friderici Engl. led to the isolation of a previously undescribed cerebroside named eloundemnoside (1), alongside with seventeen known compounds (2, 7, 12, 13, 15, 18).
Journal ArticleDOI
Rothmanniamide and other constituents from the leaves of Rothmannia hispida (K.Schum.) fagerl. (Rubiaceae) and their chemophenetic significance
Argan Kelly Nkwenti Wonkam,Argan Kelly Nkwenti Wonkam,Cyrille Armel Njanpa Ngansop,Steven Collins Njonte Wouamba,Jean-Bosco Jouda,Jean-Bosco Jouda,Gervais Mouthé Happi,Gervais Mouthé Happi,Fabrice Fekam Boyom,Norbert Sewald,Bruno Ndjakou Lenta +10 more
TL;DR: The chemical investigation of the CH2Cl2/MeOH (1:1) extract of the leaves of Rothmannia hispida led to the isolation of a new ceramide rothmanniamide and a naturally isolated alkyl cinnamate derivative n-heptadecyl-4-hydroxy-trans-cinnamate (2), along with fifteen known compounds.
Journal ArticleDOI
Chemical constituents of two Cameroonian medicinal plants: Sida rhombifolia L. and Sida acuta Burm. f. (Malvaceae) and their antiplasmodial activity.
Blaise Cedric Kamdoum,Ingrid Konga Simo,Steven Collins Njonte Wouamba,Brice Tchatat Tali,Bathelemy Ngameni,Ghislain W. Fotso,Pantaleon Ambassa,Fekam Boyom Fabrice,Bruno Ndjakou Lenta,Norbert Sewald,Bonaventure T. Ngadjui +10 more
TL;DR: An extensive phytochemical investigation of the EtOH/H2O (7:3) extracts of Sida rhombifolia L. f. and Sida acuta Burm. as mentioned in this paper yielded a previously undescribed ceramide named rombifoliamide (1) and a xyl...
References
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Journal ArticleDOI
Methods for in vitro evaluating antimicrobial activity: A review
TL;DR: An exhaustive list of in vitro antimicrobial susceptibility testing methods and detailed information on their advantages and limitations are reported.
Journal ArticleDOI
A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae).
Ngeh J. Toyang,Robert Verpoorte +1 more
TL;DR: Vernolide A is so far the most promising single agent from a Vernonia species that has potential for development into an anticancer agent and Vernonia amygdalina was identified as the most frequently used member of the Vernonia genus.
Journal ArticleDOI
Structural determination of glycosphingolipids as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisional-activated dissociation on a triple stage quadrupole instrument.
Fong-Fu Hsu,John Turk +1 more
TL;DR: Structural characterization of glycosphingolipids as their lithiated adducts using low-energy collisional-activated dissociation (CAD) tandem mass spectrometry with electrospray ionization (ESI) is described to permit unequivocal identification of cerebrosides, di-, trihexosyl ceramides and globosides.
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Evaluation of antioxidant activity and the fatty acid profile of the leaves of Vernonia amygdalina growing in South Africa
TL;DR: The leaves of Vernonia amygdalina were examined for antioxidant activity and analyzed for their fatty acids content as mentioned in this paper using transesterification and GC-MS analysis, 12 essential fatty acids were identified, which accounted for 74.1% of the lipid content.
Journal ArticleDOI
Distribution of Pollen Types in Vernonia (Vernonieae: Compositae)
TL;DR: In an attempt to understand better the patterns of radiation in the genus Vernonia, pollen from over 500 species of Vernonia was examined from throughout the geographical range by light microscopy and SEM.