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Journal ArticleDOI

Voltammetric multichannel measurements using silicon fabricated microelectrode arrays

TLDR
In this paper, a modular voltammetric multichannel detection system has been developed for use in flow analysis, which consists of two different types of multi-channel potentiostats, an adjustable and a ground-fixed potentiametric.
Abstract
A modular voltammetric multichannel detection system has been developed for use in flow analysis. Two different types of multichannel potentiostats, an adjustable and a ground-fixed potentiostat, are realized. Both types work with up to sixteen independent working electrodes at one chip electrode array and are controlled through a personal computer and a microcontroller. Simultaneous difference pulse and cyclic voltammetric procedures are realized. Platinum thin-film array electrodes have been arranged on silicon wafers as pairs of interdigitated microband electrodes (interdigitated array electrodes; IDA) with an interelectrode gap in the submicrometer range. Furthermore the multichannel electrodes in a flow system were used to characterize the highly sensitive flow profiles and flow rate measurements using redox mediators. A brief description of applying the multichannel device for ‘window’ stripping of heavy metals is given.

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Citations
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Journal ArticleDOI

Cross-reactive chemical sensor arrays.

TL;DR: Conventional approaches to chemical sensors have traditionally made use of a “lock-and-key” design, wherein a specific receptor is synthesized in order to strongly and highly selectively bind the analyte of interest.
Journal ArticleDOI

Electrical Detection of Viral DNA Using Ultramicroelectrode Arrays

TL;DR: The silicon-based electrical biochip array for voltammetric detection of redox molecules produced by enzyme-labeled affinity binding complexes is shown and is shown for the detection of virus DNA in real unpurified multiplex PCR samples.
Journal ArticleDOI

Miniaturization in functional genomics and proteomics

TL;DR: Miniaturization of biological assays is an important prerequisite to achieve these goals in the near future and is also required to dissect the regulatory processes in high-throughtput and with low cost.
Journal ArticleDOI

DNA arrays, electronic noses and tongues, biosensors and receptors for rapid detection of toxigenic fungi and mycotoxins: A review

TL;DR: An overview of how microsystem technology tools can be applied to the development of rapid, out–of–laboratory measurement capabilities for the determinations of toxigenic fungi and mycotoxins in foodstuffs is presented.
References
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Journal ArticleDOI

Digital Simulation of the Measured Electrochemical Response of Reversible Redox Couples at Microelectrode Arrays: Consequences Arising from Closely Spaced Ultramicroelectrodes

TL;DR: In this article, the effect of variations in electrode geometry on the current response was investigated in the case of an array of closely spaced ultramicroelectrode arrays, and it was shown that the collection efficiency depends on the gap gap rather than electrode wldth.
Journal ArticleDOI

Electrochemical behavior of reversible redox species at interdigitated array electrodes with different geometries: consideration of redox cycling and collection efficiency

TL;DR: Des electrodes IDA avec different parametres geometriques sont fabriques par lithographie et appliquees a des mesures de voltammerie cyclique and de chronoamperometrie d'especes redox as mentioned in this paper.
Journal ArticleDOI

Theory of ultramicroelectrodes

Koichi Aoki
- 01 Sep 1993 - 
TL;DR: In this article, the theory of mass transport at ultramicroelectrodes that have broken through several experimental limitations of electrochemical measurements is described. And the steady-state current at a disk, a band array, a ring, and a recess electrode is analyzed.
Journal ArticleDOI

Interdigitated array microelectrodes for the determination of enzyme activities

TL;DR: In this article, an array of closely spaced interdigitated microelectrodes was applied to the sensitive detection of reversible redox couples, where the measurement is based on the redox cyclization between the adjacent microband electrodes of the IDA, when both the respective oxidation and reduction potential are applied at the electrode pairs.
Journal ArticleDOI

Quantitative analysis of individual neurons by open tubular liquid chromatography with voltammetric detection.

TL;DR: A method is described for the determination of trace levels of organic compounds in individual cells by open tubular liquid chromatography with voltammetric detection that is at least as reliable as other methods that have been applied to single cells and considerably more sensitive.
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