Water deficit effect on the accumulation of biomass and artemisinin in annual wormwood(Artemisia annua L., Asteraceae)
TLDR
It is suggested that moderate water deficit prior to harvesting the crop may not only reduce time and costs in drying the crop, but can also induce artemisinin accumulation, both of which increase crop profit margins.Abstract:
Despite the importance of Artemisia annua L. as the only source of the anti-parasitic drug artemisinin, little is known on the effects of biotic and abiotic stress on artemisinin accumulation. Water deficit is the most limiting factor on plant growth, however it can trigger secondary metabolite accumulation, depending on the plant growth stage and intensity. A. annua cultivated in growth chambers was submitted to five water deficit treatments (watered, 14, 38, 62 e 86 hours without irrigation). Water deficits of 38 and 62 hours (Yw = -1.39 and -2.51 MPa, respectively) increased leaf artemisinin content, but only 38 hours led to a significant increase in both leaf and plant artemisinin (29%), with no detriment to plant biomass production. The other treatments had no effect on, or decreased artemisinin accumulation. A. annua plants tolerated well water deficit treatments, including the most severe water deficit applied (Yw -3.97 MPa or 86 hs without irrigation) and recovered their turgor pressure after rehydration. These results suggest that moderate water deficit prior to harvesting the crop may not only reduce time and costs in drying the crop, but can also induce artemisinin accumulation, both of which increase crop profit margins. Results also suggest that artemisinin could be part of A. annua chemical system of defense against water deficit.read more
Citations
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Journal ArticleDOI
Effect of prolonged water stress on specialized secondary metabolites, peltate glandular trichomes, and pathway gene expression in Artemisia annua L.
TL;DR: Results revealed that artemisinin, arteannuin-B, artemisinic acid, dihydroartemisinic Acid and essential oil content were positively controlled by the growth and development however negatively modulated by water deficit stress.
Journal ArticleDOI
Cloning and characterization of AabHLH1, a bHLH transcription factor that positively regulates artemisinin biosynthesis in Artemisia annua
Yunpeng Ji,Jingwei Xiao,Yalin Shen,Dongming Ma,Zhen-Qiu Li,Gaobin Pu,Xing Li,Lili Huang,Benye Liu,Hechun Ye,Hong Wang +10 more
TL;DR: Biochemical analysis demonstrated that the AabHLH1 protein was capable of binding to the E-box cis-elements, present in both ADS and CYP71AV1 promoters, and possessed transactivation activity in yeast, suggesting that Aab HLH1 can positively regulate the biosynthesis of artemisinin.
Proceedings ArticleDOI
MORFISIOLOGIA DE MANJERICÃO EM CONDIÇÕES DE DÉFICIT HÍDRICO ASSOCIADO com BACTÉRIAS Burkholderia spp
Rita de Cássia Monteiro Batista,Jesimiel Gomes Barbosa,Júlia Kuklinsky-Sobral,Josabete Salgueiro Bezerra de Carvalho +3 more
TL;DR: In this article, a tratamento of Ocimumbasilicum L. (Ociminea-basilicum) was carried out on a mix of manjericão plants in a UAG-UFRPE environment.
Journal ArticleDOI
Uncovering the hidden facets of drought stress: secondary metabolites make the difference.
Ülo Niinemets,Ülo Niinemets +1 more
TL;DR: Diverse responses in secondary chemistry might be the only modifications standing out from routine patterns, making these changes often hard to explain and predict, as the study of McKiernan et al. (2015) demonstrates.
Journal ArticleDOI
Understanding the consequence of environmental stress for accumulation of secondary metabolites in medicinal and aromatic plants
TL;DR: It is tried to figure out how abiotic stresses affect the production of secondary metabolites in medicinal and aromatic plants, which are involved in plant defence system for survival.
References
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Journal ArticleDOI
The dilemma of plants: To grow or defend.
TL;DR: A conceptual model of the evolution of plant defense is concluded, in which plant physioligical trade-offs interact with the abiotic environment, competition and herbivory.
Journal ArticleDOI
Qinghaosu (artemisinin): an antimalarial drug from China
TL;DR: Derivatives of QHS, such as dihydroqinghaosu, artemether, and the water-soluble sodium artesunate, appear to be more potent than QHS itself, and offer promise as a totally new class of antimalarials.
Book
Water Relations of Plants and Soils
Paul J. Kramer,John S. Boyer +1 more
TL;DR: This book is a useful introduction for students, teachers, and investigators in both basic and applied plant science, including botanists, crop scientists, foresters, horticulturists, soil scientists, and even gardeners and farmers who desire a better understanding of how their plants grow.
Book
Introduction to ecological biochemistry
TL;DR: The Plant and Its Biochemical Adaptation to the Environment, and Higher Plant-Lower Plant Interactions: Phytoalexins and Phytotoxins.
Book
Physiological Plant Ecology: Ecophysiology and Stress Physiology of Functional Groups
TL;DR: In this article, an extensive chapter deals with the effects of natural and anthropogenic stress factors on plant ecophysiology, focusing on the ways the different plant species and functional types react in various locations and in all climatic zones.
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