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This article is published in Optical Engineering.The article was published on 2001-03-01 and is currently open access. It has received 58 citations till now. The article focuses on the topics: Photonics.read more
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The effect of pain on cognitive function: a review of clinical and preclinical research.
TL;DR: The anatomical, neurochemical and molecular substrates common to both cognitive processing and supraspinal pain processing are described, and the evidence for their involvement in pain-related cognitive impairment is presented.
Journal ArticleDOI
Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease
TL;DR: There is a convergence of effects of cannabinoids, acting via cell surface and nuclear receptors, on immune cell function which provides promise for the targeted therapy of a variety of immune, particularly neuroinflammatory, diseases.
Journal ArticleDOI
Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.
Jae Won Chang,Micah J. Niphakis,Kenneth M. Lum,Armand B. Cognetta,Chu Wang,Megan L. Matthews,Sherry Niessen,Matthew W. Buczynski,Loren H. Parsons,Benjamin F. Cravatt +9 more
TL;DR: A distinct class of O-hexafluoroisopropyl (HFIP) carbamates are reported that inhibits MAGL in vitro and in vivo with excellent potency and greatly improved selectivity, including showing no detectable cross-reactivity with FAAH.
Journal ArticleDOI
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
TL;DR: Recent studies suggesting that cannabidiol may have utility in treating a number of human diseases and disorders now known to involve activation of the immune system and associated oxidative stress, as a contributor to their etiology and progression are discussed.
Journal ArticleDOI
The Impact of Literacy Coaches: What Teachers Value and How Teachers Change
TL;DR: This article analyzed interviews with 35 teachers who participated in a statewide professional development effort, the South Carolina Reading Initiative, and found that teachers valued how the coaches created a space for collaboration, provided ongoing support, and taught about research-based instructional strategies.