Journal ArticleDOI
Withania Somnifera (Ashwagandha), a Rejuvenating Herbal Drug Which Enhances Survival During Stress (an Adaptogen)
Niraj Kumar Singh,R. Nath,A. Lata,Suriya P. Singh,R. P. Kohli,Krishna P. Bhargava +5 more
- Vol. 20, Iss: 1, pp 29-35
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TLDR
Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties and appears to induce a state of non-specifically increased resistance (SNIR) during stress.Abstract:
Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties. Pretreatment with this drug increased the swimming endurance in mice. It prevented gastric ulcers induced chemically or by stress in rats. Milk-induced leucocytosis was also prevented in mice. The drug prevented increase in adrenal weight and decrease in ascorbic acid and Cortisol content of adrenals during stress. It appears to induce a state of non-specifically increased resistance (SNIR) during stress.read more
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Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.
TL;DR: Preliminary studies have found various constituents of ashwagandha exhibit a variety of therapeutic effects with little or no associated toxicity, indicating this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects.
Journal ArticleDOI
Adaptogenic properties of six rasayana herbs used in Ayurvedic medicine.
TL;DR: Some of the problems in evaluation of adaptogens which have precluded their inclusion as clinically useful drugs are discussed.
Journal ArticleDOI
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.
Alexander Panossian,Thomas Efferth,A.N. Shikov,Olga N. Pozharitskaya,Kenny Kuchta,Pulok K. Mukherjee,Subhadip Banerjee,Michael Heinrich,Wanying Wu,De-An Guo,Hildebert Wagner +10 more
TL;DR: The evolution of the adaptogenic concept has led back to basics of TMS and a new level of understanding of holistic approach, which provides a rationale for their use in stress‐induced and aging‐related diseases.
Journal ArticleDOI
Adaptogenic effect of Bacopa monniera (Brahmi)
TL;DR: It is concluded that the standardized extract of B. monniera possesses a potent adaptogenic activity against acute and chronic stress models in rats, and pretreatment with higher dose significantly reversed CS-induced changes in ulcer index, adrenal gland weight, CK, and AST.
Journal ArticleDOI
Effect of Withania somnifera (L. Dunal) root as a feed additive on immunological parameters and disease resistance to Aeromonas hydrophila in Labeo rohita (Hamilton) fingerlings
TL;DR: The results suggest that the W. somnifera root powder have a stimulatory effect on immunological parameters and increases disease resistance in L. rohita fingerlings against A. hydrophila infection.
References
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Book
Indian Medicinal Plants
TL;DR: Indian medicinal plants/, Indian medicinal plants /, مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
Journal ArticleDOI
The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenylhydrazine derivative of dehydroascorbic acid
Joseph H. Roe,Carl A. Kuether +1 more
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New substances of plant origin which increase nonspecific resistance
I I Brekhman,I V Dardymov +1 more
Journal ArticleDOI
The estimation of small amounts of corticosterone in rat plasma.
TL;DR: This method uses the double extraction technique of Silber and Porter and a modification of the fluorescence technique described by Sweat for analysis of plasma corticosteroids in the rat.
Journal ArticleDOI
Synergism Between Gold and Restraint for Rapid Production of Stress Ulcers in Rats.
Edward C. Senay,Robert J. Levine +1 more
TL;DR: The simplicity of the technique permits an experienced operator to immobilize an animal in approximately 30 to 45 seconds, and use of the plastic box permits immobilization in a relatively uniform volume.
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