Journal ArticleDOI
Y a-t-il une place pour la cryopréservation ovocytaire après le traitement du cancer ?
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TLDR
Pour les patientes qui n’ont pu beneficier de techniques de preservation de the fertilite avant le traitement du cancer et qui ont retrouve des cycles spontanes, pourrait se discuter l’option de the congelation d’ovocytes a distance of the maladie.Abstract:
The number of young cancer women theoretically eligible for fertility preservation before chemotherapy is steadily increasing. Nevertheless, the number of patients who can really benefit from complex ART techniques such as ovarian tissue or oocyte/embryo cryopreservation remains very low mainly because of a too short time-interval between the cancer diagnosis and its treatment. Lack of adequate information regarding post treatment infertility risk and logistical difficulties to access to a highly specialized cryopreservation centre are also reasons of importance. It is now well-established that these patients are at high risk of infertility even if they return to a normal ovarian function. Therefore, for patients who could not benefit from fertility preservation before cancer treatment, and who have recovered spontaneous menstrual cycle, one might raise the question of oocyte freezing once the cancer cured.read more
Citations
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Journal ArticleDOI
Egg Freezing in Childhood and Young Adult Cancer Survivors.
Francesca Filippi,Cristina Meazza,Alessio Paffoni,Francesco Raspagliesi,Monica Terenziani,Edgardo Somigliana +5 more
TL;DR: The case of a young female patient with cancer who survived 2 chemotherapies for 2 distinct cancers and who was diagnosed with reduced ovarian reserve is described and the success obtained suggests consideration of egg freezing as an alternative fertility-preservation procedure in prepubertal and young adolescent girls scheduled for chemotherapy.
References
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Journal ArticleDOI
Anti-Müllerian Hormone Inhibits Initiation of Primordial Follicle Growth in the Mouse Ovary
Alexandra L. L. Durlinger,Maria J. G. Gruijters,Piet Kramer,Bas Karels,Holly A. Ingraham,Mark W. Nachtigal,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +8 more
TL;DR: It is suggested that AMH inhibits initia- tion of primordial follicle growth and therefore functions as an inhibitory growth factor in the ovary during these early stages of folliculogenesis.
Journal ArticleDOI
Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial
TL;DR: This controlled-randomized, clinical trial confirmed the effectiveness of oocyte cryo-storage in an ovum donation programme, failing to demonstrate the superiority of using fresh oocytes with respect to the use of vitrified egg-banked ones in terms of OPR, but instead confirmed the non-inferiority of Vitrified oocytes.
Journal ArticleDOI
Embryo development of fresh ‘versus’ vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study
Laura Rienzi,Stefania Romano,Laura Albricci,Roberta Maggiulli,Antonio Capalbo,E. Baroni,Silvia Colamaria,Fabio Sapienza,Filippo Ubaldi +8 more
TL;DR: Oocyte vitrification procedure followed by ICSI is not inferior to fresh insemination procedure, with regard to fertilization and embryo developmental rates and ongoing clinical pregnancy is compatible with this procedure, even with a restricted number of oocytes available for insemination.
Journal ArticleDOI
A model conforming the decline in follicle numbers to the age of menopause in women
Malcolm J. Faddy,R.G. Gosden +1 more
TL;DR: This study attempts to produce a biologically more realistic model of follicle disappearance and harmonizes follicle dynamics with the distribution of menopausal ages from an American survey and produces a stochastic threshold model for menopause which could be forecast with an acceptable margin of uncertainty.
Journal ArticleDOI
A Validated Model of Serum Anti-Müllerian Hormone from Conception to Menopause
TL;DR: In this article, a model of AMH concentration from conception to menopause has been presented, showing that 34% of the variation in AMH is due to age alone.