Antonio Capalbo

TL;DR: Oocyte vitrification procedure followed by ICSI is not inferior to fresh insemination procedure, with regard to fertilization and embryo developmental rates and ongoing clinical pregnancy is compatible with this procedure, even with a restricted number of oocytes available for insemination.

TL;DR: This study provides knowledge for a better laboratory and clinical management of blastocyst stage PGS cycles suggesting that the commonly used parameters ofblastocyst evaluation are not good enough indicators to improve the selection among euploid embryos.

TL;DR: Oocyte vitrification is an efficient and reliable approach, with consistent results between centers and predictable DRs, and should be applied routinely for various indications.

TL;DR: This work generates genome-wide maps of crossovers and chromosome segregation patterns by recovering all three products of single female meioses, and uncovers a new reverse chromosome segregation pattern in which both homologs separate their sister chromatids at meiosis I.

TL;DR: The authors show that chromosome structure erodes only with advancing age, acting as a “molecular clock” for reproductive senescence, and suggest that chromosomal errors originating in oocytes determine the curve of natural fertility in humans.