H
Holly A. Ingraham
Researcher at University of California, San Francisco
Publications - 112
Citations - 14551
Holly A. Ingraham is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Receptor & Steroidogenic factor 1. The author has an hindex of 56, co-authored 107 publications receiving 13705 citations. Previous affiliations of Holly A. Ingraham include Howard Hughes Medical Institute & Boston University.
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Journal ArticleDOI
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype.
Holly A. Ingraham,Ruoping Chen,Harry J. Mangalam,Harry P. Elsholtz,Sarah E. Flynn,Chijen R. Lin,Donna M. Simmons,Donna M. Simmons,Larry W. Swanson,Michael G. Rosenfeld +9 more
TL;DR: The structure of Pit-1 and its recognition elements suggests that metazoan tissue phenotype is controlled by a family of transcription factors that bind to related cis-active elements and contain several highly conserved domains.
Journal ArticleDOI
Expression of a large family of POU-domain regulatory genes in mammalian brain development.
Xi He,Maurice N. Treacy,Donna M. Simmons,Donna M. Simmons,Holly A. Ingraham,Holly A. Ingraham,Larry W. Swanson,Larry W. Swanson,Michael G. Rosenfeld,Michael G. Rosenfeld +9 more
TL;DR: The identification of multiple new members of a large family of POU-domain genes expressed in adult brain are reported, and it is documented that all the known mammalian Pou- domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system.
Journal ArticleDOI
Anti-Müllerian Hormone Inhibits Initiation of Primordial Follicle Growth in the Mouse Ovary
Alexandra L. L. Durlinger,Maria J. G. Gruijters,Piet Kramer,Bas Karels,Holly A. Ingraham,Mark W. Nachtigal,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +8 more
TL;DR: It is suggested that AMH inhibits initia- tion of primordial follicle growth and therefore functions as an inhibitory growth factor in the ovary during these early stages of folliculogenesis.
Journal ArticleDOI
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products
Winship Herr,Richard A. Sturm,Roger G. Clerc,Lynn M. Corcoran,David Baltimore,Phillip A. Sharp,Holly A. Ingraham,Michael G. Rosenfeld,Michael Finney,Gary Ruvkun +9 more
TL;DR: The POU domain is a novel bipartite DNA-binding structure in which the POU homoeo and POU-specific regions form two subdomains that are both required for DNA binding but are held together by a flexible linker.
Journal ArticleDOI
Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases.
TL;DR: Analysis of the developmental profile of steroidogenic factor-1 (SF-1), a nuclear receptor that regulates the steroid hydroxylases, suggests that SF-1 plays a role in gonadal development distinct from regulating the steroidogenic enzymes.