Is zinc in collagen peptides?
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| Papers (15) | Insight |
|---|---|
34 Citations | It is shown that the peptide bond is likely to be the main target in collagen. |
| The location of the zinc site at the amino terminus, immediately adjacent to the precursor cleavage site, suggests the possibility that the zinc may be involved in activation of the antiangiogenic activity following cleavage from the inactive collagen XVIII precursor or in the cleavage process itself. | |
13 Citations | The reduction of zinc in the pancreatic tissue in CAP may enhance collagen synthesis and increase fibrous tissue deposition in this organ. |
38 Citations | The results of this study show that in HSC, the chelation of zinc triggers a progression of collagen synthesis and this involves the depletion of intracellular GSH levels after the addition of DTPA. |
| The present data suggest that peroral zinc treatment has a direct and selective inhibitory effect on carbon tetrachloride-induced collagen accumulation in rat liver. | |
96 Citations | These data show that zinc deficiency decreases bone collagen turnover and probably accounts for the leg deformities seen in zinc-deficient chicks. |
| In addition the high zinc levels in collagen beneath this material may be attributed to the binding of the eugenol component. | |
13 Citations | Therefore, the results demonstrate that zinc supplementation suppresses BDL-induced liver fibrosis through both inhibiting collagen production and enhancing collagen degradation. |
21 Citations | The results of this study suggest that most of the zinc atoms detected were attached to hydroxyapatite and not to collagen. |
49 Citations | Zinc is likely a cofactor for 2 kinds of cross-linking interactions; one involving direct binding between laminin and collagen type IV and the other a ternary complex of laminin-entactin-collagen type IV. |
| Cathepsin K-induced dentin collagen degradation can be strongly inhibited by zinc. | |
| The results show that zinc does not have a direct acceleratory effect on either cellular proliferation or collagen biosynthesis in human skin fibroblasts in vitro. | |
| Neither inhibition of polysomal protein synthesis nor increased degradation of mature collagen fibers was found to play any major role in the effect of zinc. | |
| Zinc can prevent collagen hydrolysis by MMPs. | |
22 Citations | To our knowledge, this is the first report on cyclic phosphinic peptides and on their activities as inhibitors of a zinc protease. |
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