T
Thomas Boehm
Researcher at Max Planck Society
Publications - 179
Citations - 11873
Thomas Boehm is an academic researcher from Max Planck Society. The author has contributed to research in topics: Gene & T cell. The author has an hindex of 56, co-authored 167 publications receiving 10987 citations. Previous affiliations of Thomas Boehm include University of Freiburg.
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Journal ArticleDOI
Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen.
Stephanie Kruetzmann,Maria Manuela Rosado,Holger Weber,Ulrich Germing,Olivier Tournilhac,Hans-Hartmut Peter,Reinhard Berner,Anke M J Peters,Thomas Boehm,Alessandro Plebani,Isabella Quinti,Rita Carsetti +11 more
TL;DR: The physiological and transient predisposition to pneumococcal infections of young children (0–2 yr) is associated with the lack of circulating IgM memory B cells and of serum antipolysaccharide IgM.
Journal ArticleDOI
New member of the winged-helix protein family disrupted in mouse and rat nude mutations
TL;DR: The whn gene, designated whn, encodes a new member of the winged-helix domain family of transcription factors and is disrupted on mouse nu and rat rnuN alleles, the first member of this class of genes to be implicated in a specific developmental defect in vertebrates.
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Elephant shark genome provides unique insights into gnathostome evolution
Byrappa Venkatesh,Byrappa Venkatesh,Alison P. Lee,Vydianathan Ravi,Ashish K. Maurya,Michelle M. Lian,Jeremy B. Swann,Yuko Ohta,Martin F. Flajnik,Yoichi Sutoh,Masanori Kasahara,Shawn Hoon,Vamshidhar Gangu,Scott William Roy,Manuel Irimia,Vladimir Korzh,Igor Kondrychyn,Zhi Wei Lim,Boon Hui Tay,Sumanty Tohari,Kiat Whye Kong,Shufen Ho,Belen Lorente-Galdos,Belen Lorente-Galdos,Javier Quilez,Javier Quilez,Tomas Marques-Bonet,Tomas Marques-Bonet,Brian J. Raney,Philip W. Ingham,Alice Tay,LaDeana W. Hillier,Patrick Minx,Thomas Boehm,Richard K. Wilson,Sydney Brenner,Wesley C. Warren +36 more
TL;DR: The whole-genome analysis of a cartilaginous fish, the elephant shark (Callorhinchus milii), finds that the C. milii genome is the slowest evolving of all known vertebrates, and features extensive synteny conservation with tetrapod genomes, making it a good model for comparative analyses of gnathostome genomes.
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MHC Class I Peptides as Chemosensory Signals in the Vomeronasal Organ
Trese Leinders-Zufall,Peter A Brennan,Patricia Widmayer,Prashanth Chandramani S.,Andrea Maul-Pavicic,Martina Jäger,Xiao-Hong Li,Heinz Breer,Frank Zufall,Thomas Boehm +9 more
TL;DR: It is shown that small peptides that serve as ligands for major histocompatibility complex (MHC) class I molecules function also as sensory stimuli for a subset of vomeronasal sensory neurons located in the basal Gao- and V2R receptor–expressing zone of the vomer onasal epithelium.
Journal ArticleDOI
Two genetically separable steps in the differentiation of thymic epithelium.
Michael Nehls,Bruno Kyewski,Martin Messerle,Ralph Waldschütz,Kerstin Schüddekopf,Andrew J.H. Smith,Thomas Boehm +6 more
TL;DR: The WHN transcription factor was shown to be the product of the nude locus and these results define the first genetically separable steps during thymic epithelial differentiation.