Showing papers on "Mentha pulegium published in 2019"
TL;DR: Results indicate that aqueous extract of Mentha pulegium (L.) are effective reducing agents for green synthesis of ZnO NPs with significant antimicrobial potential.
79 citations
TL;DR: A green approach for the encapsulation of Mentha pulegium essential oil in commercial baker's yeast and its evaluation as a pesticide against the insect pest Myzus persicae are presented.
Abstract: A green approach for the encapsulation of Mentha pulegium essential oil in commercial baker’s yeast and its evaluation as a pesticide against the insect pest Myzus persicae are presented. Upon treating aqueous yeast cell dispersion with the essential oil, the formation of essential-oil-loaded microparticles of about 9 μm is observed, with a loading capacity ranging from 29 to 36%, depending upon the encapsulation conditions. The thermal properties of the microparticles were characterized using differential scanning calorimetry and thermogravimetric analysis, confirming the protection of the essential oil from the cells. Encapsulation prolonged the insecticidal activity of the essential oil by 3 days.
49 citations
TL;DR: This review focus on summarizing and systematizing the composition and efficacy as a biocide of M. pulegium essential oil and the developments of the last decade regarding the usage of M.'s pulegum essential oil as an alternative to pesticides.
41 citations
TL;DR: Instrumental neutron activation analysis has been used to determine the concentration of some toxic chemical elements in a variety of aromatic plants samples collected from Djelfa region, and can be useful for therapeutics and pharmaceutical purposes.
Abstract: Instrumental neutron activation analysis (INAA) has been used to determine the concentration of some toxic chemical elements in a variety of aromatic plants samples collected from Djelfa region. In the present work, eight medicinal plants were examined, such as Artemisia herba-alba Asso., Artemisia compestris L., Laurus nobilis L., Origanum vulgare L., Mentha spicata L., Rosmarinus officinalis L., Mentha pulegium L., and Pistacia lentiscus L. The levels of toxic elements were compared to their daily total intake; Arsenic was present in all plant species examined, with a concentration ranging from 0.18 to 5.44 μg g− 1. Bromine was also detected in all the medicinal plant species, with high concentrations, compared to arsenic except in the case of Laurus nobilis that has the highest concentration of arsenic. Cerium, cobalt, chromium, and antimony were presented in all plant species. The exactitude of the results was assessed by analyzing the certified reference material of SRM-NIST 1573a and CRM GB07605 (GSV4). These data analysis for this medicinal plant can be useful for therapeutics and pharmaceutical purposes.
37 citations
TL;DR: It was demonstrated that fumigant toxicity varied with insect species, essential oil concentration and exposure time, and that M. pulegium essential oil was more toxic to the two stored date pests.
Abstract: The aim of this research was to explore the chemical composition and evaluate the insecticidal activities of Ruta graveolens, Mentha pulegium and Ocimum basilicum leaves essential oils from south of Tunisia. Fumigant toxicities were assessed toward the most important and destructive insects attacking dates in storage in Tunisia namely Ectomyelois ceratoniae and Ephestia kuehniella. GC–MS analyses showed that major compounds of O. basilicum essential oil were linalool (29.23%), methyl cinnamate (18.97%) and eugenol (5.84%), followed by 1,8-cineole (5.74%), α-cadinol (5.69%), estragol (4.72%) and α-bergamotene (4.24%), whereas M. pulegium essential oil had 1,8-cineole (14.60%), p-menthan-3-one (14.9%), piperitenone (11.4%), carene (10.19%), menthol (8.76%), trans-caryophyllene (6.64%) and menthyl alcohol (6.14%) as major components. The essential oil extracted from R. graveolens was remarkably rich in hydrocarbon ketones (52.5%) mainly 1-nonene (19.4%), 2-undecanone (16.22%) and 2-nonanone (11.9%). Results demonstrated that fumigant toxicity varied with insect species, essential oil concentration and exposure time. Lethal concentration (LC50) values of O. basilicum, M. pulegium and R. graveolens were, respectively, 0.96, 0.3 and 1.02 μL/L air on E. kuehniella and were 1.23, 0.31 and 1.97 μL/L air on E. ceratoniae. M. pulegium essential oil was more toxic to the two stored date pests E. kuehniella and E. ceratoniae at all tested concentrations.
28 citations
TL;DR: Antibacterial studies showed good activity against four Gram positive and Gram negative bacteria: Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, as well as good inhibitory properties (MIC), suggesting that Algerian M. pulegium and L. steochas EOs can be used in food and pharmaceutical industries as antimicrobial and preservative agents.
Abstract: The aim of the present study was to determine the chemical composition, antioxidant and antimicrobial activities of Algerian Mentha pulegium L. and Lavandula stoechas L. essential oils (EOs...
18 citations
TL;DR: Mentha pulegium leaves extract was used as a green reducing agent for the synthesis of silver-nanoparticles and used as an adsorbent for preconcentration of trace levels of cadmium (ІІ).
Abstract: In this paper, Mentha pulegium leaves extract was used as a green reducing agent for the synthesis of silver-nanoparticles. The synthesized silver-nanoparticles were characterized by UV–VIS spectro...
13 citations
TL;DR: Application of M. Pulegium extract on second degree burn wounds significantly decreased burn surface area and increased fibroblasts in comparison to simple dressing, and had a positive effect on healing process of second degree burns.
Abstract: Background Burn is one of the most common injuries and the 4th common cause of trauma globally. This study was designed to evaluate the effect of the Mentha pulegium extract on second degree burn injuries in rats assessing histopathologic and macroscopic. Methods M. Pulegium extract dressings was used as a treatment to deep dermal contact burns in rats, compared with two control groups of vaseline dressing and simple dressing by normal saline. After creating second-degree burn on the dorsum of rats, the treatments were applied for 15 min in three groups. Wound dressings were performed on days 1, 3, 7, 14 and 21st and at the same time macroscopic assessment was performed using a digital camera and software processing of photos. Pathologic evaluation of skin specimens was undertaken on days 1, 3,7, 14 and 21st. Wound healing parameters such as epithelialization, angiogenesis, granulation tissue formation, inflammatory cells were compared between these 3 groups. Results Application of M. Pulegium extract on second degree burn wounds significantly decreased burn surface area and increased fibroblasts in comparison to simple dressing. There was not any statistically significant relationship between M. Pulegium extract treated group and vaseline treated or simple dressing groups on other wound healing parameters. Conclusion This study delineated that M. Pulegium extract had a positive effect on healing process of second degree burns.
13 citations
TL;DR: Interestingly, there are no differences between toxicity of both EOs and that of the chemical insecticide imidacloprid used as positive control which led to aphid’s mortality between 42 and 56 %, which suggests that both E Os can substitute chemicals for a better control of A. spiraecola and A. gossypii.
Abstract: Essential oils (EOs) of Mentha pulegium L., (Lamiales: Lamiaceae) and Pistacia lentiscus L., (Sapindales: Anacardiaceae) were studied for their insecticidal activities against the spirae ap...
12 citations
TL;DR: Evidence suggests that the piperitone-based chemotype can be a valuable source for new crop protection products with the aim of being compatible with modern Integrated Pest Management strategies.
Abstract: Essential oils of Mentha pulegium (Lamiaceae) have shown a high potential for use in pest control. In the present study we examined the comparative potential of the M. pulegium essential oils representing pulegone (EO1) and piperitone (EO2) chemotypes for the control of three serious crop pests, along with their side effects on a beneficial insect. In the case of Tetranychus urticae, the mortality rate of females sprayed at the concentration of 500 μL/L was 68.5% and 71%, for EO1 and EO2 respectively, while the mortality rate at 1000 μL/L was 86% and 92.5%, which were significantly higher compared to the control (21%). In the experiments on Aphis gossypii, the sprayings were held under greenhouse conditions at 1000 μL/L. The mortality rate caused by EO1 was 82% and that of EO2 was 88%. In the control treatment dead aphids were not observed. The results on the third pest, Aphis spiraecola, showed a mortality rate of 40% and 48% for the EO1 and EO2 chemotype, respectively, at 500 μL/L. Interestingly, the mortality caused by both essential oils on the polyphagous predator Nesidiocoris tenuis was not significantly different to the control treatment. All this evidence suggests that the effects of both M. pulegium essential oil chemotypes are equally effective in the control of the pests tested, causing only minor effects on a beneficial insect. Therefore, due to the constraints reported for the pulegone use in pest control, the piperitone-based chemotype can be a valuable source for new crop protection products with the aim of being compatible with modern Integrated Pest Management strategies.
11 citations
TL;DR: In this article, the secondary metabolite products and in vitro antibacterial and anti-fungal activities of Mentha pulegium were analyzed and the authors evaluated the anti-microbial activity by determining the zone of inhibition against bacteria, fungi and yeast.
Abstract: The aims of our research were analysis of the secondary metabolite products and in vitro antibacterial and anti-fungal activities. Infectious diseases which are one of the main causes of morbidity and mortality worldwide represent a critical problem to health. Pharmacological industries have produced number of new-antibiotics in the last three decades, but microbial resistance to these antibiotics has increased because of genetic ability of the bacteria to acquire and transmit the resistance against therapeutic agents. Mentha pulegium is a species of flowering plant in the family Lamiaceae. The FTIR analysis of Mentha pulegium leaves proved the presence of alkenes, alkyl halides, aromatic, and amide which shows major peaks at 958.62, 985.62, 1012.63, 1026.13, 1093.64, 1242.16, 1255.66, 1593.20, 1606.70 and 2362.80. In the current study, the anti-microbial activity of Mentha pulegium methanolic extract was evaluated by determining the zone of inhibition against bacteria, fungi and yeast. Maximum zone formation was against Staphylococcus aureus (5.89±0.20). Mentha pulegium was very highly active against Aspergillus terreus (6.37±0.22).
Journal Article•
TL;DR: The aim of this work was to evaluate the antihyperglycemic activity of aerial parts aqueous extract of Mentha pulegium on blood glucose levels in normal and streptozotocin(STZ)-induced diabetic rat.
Abstract: OBJECTIVE The aim of this work was to evaluate the antihyperglycemic activity of aerial parts aqueous extract (A.P.A.E) of Mentha pulegium (M. pulegium) on blood glucose levels in normal and streptozotocin(STZ)-induced diabetic rat. The glucose tolerance was evaluated in normal rats. Moreover, the histological sections and morphometric analysis at the liver and pancreas have been carried out in this investigation both in normal and STZ-diabetic rats. METHODS The effect of A.P.A.E of M. pulegium (20 mg/kg) on blood glucose levels was investigated in normal and diabetic rats (n=6). Histopathological changes in liver and pancreas were examined under phase contrast microscope and a preliminary screening for various bioactive constituents was realized according to standard methods. KEY FINDINGS Both single and repeated oral administration of A.P.A.E (20 mg/kg) caused a significant reduction in blood glucose levels in STZ-diabetic rats (p<0.0001). The morphometric analysis and histological sections realized in pancreas and liver have showed the beneficial effect of the A.P.A.E in cellular population. According to oral glucose tolerance test (OGTT), the aqueous extract has revealed an improvement of glucose tolerance in normal rat. Furthermore, the preliminary phytochemical screening of A.P.A.E of M. pulegium has demonstrated the presence of various metabolite compounds including polyphenols, flavonoids, terpenoids tannins, cyanidins, sesquiterpenes, and glycosides. CONCLUSION We conclude that the A.P.A.E of M. pulegium (20 mg/kg) exhibits a potent antihyperglycemic activity in STZ diabetic rats.
TL;DR: In this paper, the effect of different sources of zinc (algae extract, zinc sulfate, zinc multi, and zinc chelated) on herb yield, nutrient contents and their uptake, carbonic anhydrase, and essential oil production of Mentha pulegium L. is investigated.
Abstract: Background and objective Mentha pulegium L. is commonly known as pennyroyal and it is highly aromatic than any other mint. The essential oil could be considered as a possible candidate for human cancer chemotherapy. This study was carried out to evaluate the effect of different sources of zinc (algae extract, zinc sulfate, zinc multi, and zinc chelated) on herb yield, nutrient contents and their uptake, carbonic anhydrase, and essential oil production of M. pulegium plant. Materials and methods A field experiment was carried out under drip irrigated sandy soil at the Experimental Station of National Research Centre in Nubaria district, El-Behira Governorate, Egypt. Macronutrients and micronutrients contents of herb, nutrient uptake, carbonic anhydrase activity, and essential oil content were determined. Essential oil constituents were analyzed by chromatography-mass spectrometry. Results The results showed that algae extract followed by zinc multi significantly increased herb fresh and dry weight yield, nutrients content and their uptake, as well as showed the stimulatory impact on carboxylation enzyme activities. The highest essential oil yield (0.93 ml/plant and 20.67 l/ha) was recorded with algae extract, followed by zinc multi (0.80 ml/plant and 17.78 l/ha) than zinc chelate (0.50 ml/plant and 11.11 l/ha). Chromatography-mass spectrometry analyses of the essential oil showed that the essential oil composition was characterized by a high percentage of oxygenated compounds (96.83–97.33%) while the nonoxygenated compounds ranged from 2.48 to 2.89%. The major constituents of oxygenated compounds were found to be pulegone (67.75–74.43%) followed by neomenthone (10.66–17.12%). Algae extract and zinc multi produced the highest relative concentration of neomenthone (17.12 and 16.72%) and the lowest concentration of pulegone (67.75 and 67.97%). In contrast, foliar application of zinc chelated and zinc sulfate increased the biosynthesis of pulegone (74.43 and 73.98%) and decreased the percent of neomenthone (11.39 and 10.66%). Conclusion It might be concluded that the foliar application of zinc as algae extract followed by zinc multi chelated gave remarkable higher increases in herb yield, nutrients content and their uptake, carbonic anhydrase and essential oil production of M. pulegium plant.
DOI•
10 Jun 2019TL;DR: In this article, a continuation of chemical study of the essential oils of some mints grown in the Settat Morocco region: Mentha piperita, Mentha pulegium and Mentha spicata, against insects of cereals: Sitophilus Granarius, Sitophils Oryzae and Sitophius Zeamais.
Abstract: Essential oils are secondary metabolites produced by plants as a defense against phytophagous pests. These extracts contain complex compounds. The essential oils present many previous works, especially in Morocco. The present work is a continuation of chemical study of the essential oils of some mints grown in the Settat Morocco region: Mentha piperita , Mentha pulegium and Mentha spicata , against insects of cereals: Sitophilus Granarius , Sitophilus Oryzae and Sitophilus Zeamais . Experiments were conducted in the laboratory using different doses of these oils to evaluate the mortality they cause on the adults of the insects tested. The results of the sensitivity showed that the three essential oils of mint had important insecticidal properties against the pests studied. And as a result, they were able to destroy all the insects at a concentration of 2 μl/cm 3 for a duration of 24 hours of treatment.
TL;DR: In this article, the corrosion inhibition of aluminum, in 0.1 M Na 2 CO3, by Mentha pulegium essential oil, was studied using both polarization and impeda nce methods.
Abstract: The corrosion inhibition of aluminum, in 0.1 M Na 2CO3, by Mentha pulegium essential oil, was studied using both polarization and impeda nce methods. The results show that Mentha pulegium is an effective inhibitor, providing an inhibition rate of 94.16 %, with a concentration of 800 ppm. The polarization study shows that the Mentha pulegium essential oil acted as a mixed inhibitor in 0.1 M N a2CO3. The activation energy calculation has proved that the inhibitor molecules ad orbed onto the aluminum surface, according to the physisorption mechanism.
TL;DR: This poster presents a probabilistic analysis of the phytochemical properties of polymethine, which has the potential to improve the quality of life of animals and increase the chances of their survival.
Abstract: In this study we discuss Mentha pulegium shoot multiplication and the capacity of in vitro plants to produce essential oils (EOs). EO was obtained by hydrodistillation from dried leaves and flowering stems of in vitro and field-grown plants, and their chemical composition was examined by GC-MS. The differences in yield as well as quantitative and qualitative composition between the oils extracted from in vitro and field-grown plants were observed. M. pulegium EOs were evaluated for their antioxidant and antimicrobial activities. It was found that antimicrobial activity of EOs extracted from acclimated in vitro plants was higher than those from field-grown M. pulegium plants. Our aim was to perform phytochemical screening of leaves from a wild-growing plant and compare the results with material produced using biotechnological methods based on tissue culture.
10 Oct 2019
TL;DR: In this paper, the chemical composition of the leaf Essential Oils (EOs) of five plants (Ocimum basilicum, Lavandula dentata, Mentha piperita, mentha pulegium, and Laurus nobilis) was investigated to assess their potential larvicidal activity against Culex pipiens L., 1758 (Diptera, Culicidae).
Abstract: The present study was undertaken in order to determine the chemical composition of the leaf Essential Oils (EOs) of five plants (Ocimum basilicum, Lavandula dentata, Mentha piperita, Mentha pulegium, and Laurus nobilis) cultivated in Tebessa (Algeria) and to assess their potential larvicidal activity against the most abundant and investigated mosquito species, Culex pipiens L., 1758 (Diptera, Culicidae). The Essential Oils (EOs) were tested at different concentrations on newly molted 4th instar larvae. The effects of the activities of Acetylcholinesterase (AChE) and Glutathione-S-Transferases (GSTs) on mortality were examined. Their chemical compositions were investigated by GC/MS. The major components of M. pulegium, L. dentata, M. piperita, O. basilicum, and L. nobilis were Pulegone (72.50%), α-Terpinolene (51.13%), Carvone (30.27%), Linalyl acetate (53.89%), and Eucalyptol (47.35%), respectively. The larval mortality was observed after 24 h of exposure. Dose-response relationship was determined for all tested plants EOs. L. nobilis EO was the most effective against C. pipiens, comparatively to the other tested oils. The enzymatic measurements performed in LC50 treated larvae revealed a neurotoxic activity and a stimulation of the detoxification system with evidenced by the inhibition of AChE and an increase in GST activity, respectively. The EOs from tested plants could be an alternative measure for the control of C. pipiens as they contain an efficient source of bioactive compounds, which are generally free from health hazards and environmental pollution.
30 Sep 2019
TL;DR: This study, based on scientific references, describes information on the antimicrobial effects of Mentha pulegium.
Abstract: Most medicines used in the treatment of human diseases today are extracted from herbs that have been considered as an herbal medicine in traditional medicine. As the use of synthetic drugs and the emergence of pathogenic strains has increased, efforts to replace chemical drugs with cost-effective herbal remedies have increased. In this regard, every year many researchers from this huge plant source are sending a range of secondary compounds to the consumer market for the treatment of human diseases. Therefore, the identification of herbs with antimicrobial effects can help to produce new drugs with a broad spectrum of effects. This study, based on scientific references, describes information on the antimicrobial effects of Mentha pulegium.
TL;DR: The results show the presence in oils of protease inhibitors, considering serine and metalloproteases (acting on clotting factors or with hemorrhagic activity), as well as phospholipase A2 (enzymes involved in inflammation and clotting processes) inhibitors of wide application in medical and biotechnology areas.
Abstract: Snake venom are widely used as laboratory tools for studies of physiological, pharmacological and toxicological mechanisms. Venoms used here are rich sources of several classes of proteases that act on factors of the coagulation cascade, fibrinogenolysis and fibrinolysis, altering the hemostatic processes, and phospholipases A2 which are involved mainly in inflammatory and clotting processes since they act hydrolyzing membrane phospholipids and may result in the release of arachidonic acid whose structure is a precursor of eicosanoids by cyclooxygenase and lipoxygenase pathways. Natural products such as essential oils are made up of active ingredients with wide application in the food, pharmaceutical and cosmetic industries. Thus, in this study evaluate the essential oils from Mentha viridis and Mentha pulegium on coagulation, fibrinogenolysis and degradation of azocasein, induced by Bothrops sp and Lachesis muta muta venoms. These oils were achieved by hydrodistillation and presented, respectively, as the main constituents linalool (40.70%), carvone (13.52%) and α-terpinene (8.56%); pulegone (50.01%), menthol (31.90%) and menthone (16.56%). The essential oils were previously incubated with Bothrops alternatus venom, for two different times, plasma was added and timing. The M. pulegium and M. viridis oils in the volume of 0.30 μL (10 min of incubation) presented greater anticlotting potential. Meanwhile, 0.15 μL the M. pulegium oil presented proclotting activity. In 20 min of incubation, both oils presented anticlotting activity with 0.15 and 0.30 μL. At azocaseinolytic assay the oil from M. pulegium reduced the activity for all evaluated venoms. The highest inhibitions were 34.33% and 39.99% for 0.6 and 1.2 μL of oil, respectively; on activity induced by B. jararacussu, M. viridis with 0.6 and 1.2 μL reduced the activity in 40.93% and 57.72%, respectively. On B. moojeni, the same volumes were responsible for inhibitions of 74.67% and 47.4%, respectively. The fibrinogenolysis induced by B. moojeni venom was totally inhibited by both oils in the evaluated proportions. The results show the presence in oils of protease inhibitors, considering metalloproteases (mainly with thrombin-like and hemorrhagic activity) and serineproteases (actuating on clotting factors), as well as phospholipase A2 inhibitors (involved in inflammation and clotting processes) of wide application in medical and biotechnology areas.
TL;DR: In this paper, the authors investigated the antibacterial activity of the essential oils and leaf methanolic extracts of Mentha pulegium and Glycyrrhiza foetida against five phytopathogenic bacteria.
Abstract: This research was conducted to evaluate the components of the Mentha pulegium (L) and Glycyrrhiza foetida (Desf) that were extracted by hydro distillation and analyzed using GC-MS methods. They are spontaneous plants widespread in Gharb of Morocco. The aim of the study is to investigate the antibacterial activity of the essential oils and leaf methanolic extracts of these two medicinal plants against five phytopathogenic bacteria. The evaluation of the antimicrobial activity of the two species by estimating the diameter of the inhibition zone has shown that the essential oil of M. pulegium exhibited a higher antimicrobial activity than G. foetida which varied according to the sensitivity of the phytopathogenic strains. The results obtained revealed different degrees of sensitivity toward methnolic extract. However, the methanolic extract and the essential oil of M. pulegium are more active based on the Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC). The antimicrobial activities of leaf extracts from the two plants highlighted in this study could justify their therapeutic use. These results should be strongly recommended as an alternative to a chemical compound that still represents the problem of toxic residues.