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Showing papers on "Ostium published in 2007"


Journal ArticleDOI
TL;DR: Percutaneous coronary intervention with sirolimus-eluting stents or paclitaxel-eluted stents implantation in nonbifurcation left main coronary artery lesions appears safe with a long-term major adverse clinical event rate of 7.4% and a restenosis rate of 0.9%.
Abstract: Background— The presence of a lumen narrowing at the ostium and the body of an unprotected left main coronary artery but does not require bifurcation treatment is a class I indication of surgical revascularization. Methods and Results— A total of 147 consecutive patients who had a stenosis in the ostium and/or the midshaft of an unprotected left main coronary artery (treatment of the bifurcation not required) and were electively treated with percutaneous coronary intervention and sirolimus-eluting stents (n=107) or paclitaxel-eluting stents (n=40) in 5 centres were included in this registry. In 72 patients (almost 50%), intravascular ultrasound guidance was performed. Procedural success was achieved in 99% of the patients; in 1 patient with stenosis in the left main coronary artery ostium, a >30% residual stenosis persisted at the end of the procedure, and the patient was referred for coronary artery bypass graft surgery. During hospitalization, no patients experienced a Q-wave myocardial infarction or di...

214 citations


Journal ArticleDOI
TL;DR: Coronary artery bypass grafting is avoided in all patients with coronary insufficiency and in asymptomatic patients with high-risk morphologic abnormalities and pulmonary artery translocation for single ostium without an intramural course is recommended.

104 citations


Journal ArticleDOI
TL;DR: Evaluated the time course and extent of the restenosis that occurs after an endoscopic modified Lothrop procedure and to identify factors that contribute to this process.
Abstract: Objectives: To evaluate the time course and extent of the restenosis that occurs after an endoscopic modified Lothrop procedure (EMLP) and to identify factors that contribute to this process. Study Design: Retrospective study of prospectively collected data. Methods: Seventy-seven consecutive patients undergoing EMLP between November 1998 and June 2005 with frontal ostium measurements documented intraoperatively and at follow-up visits for a minimum of 12 months were included. Data on patient demographics, medical history, comorbidities, and computed tomography scans were collected. Results: Significant restenosis of the frontal sinus neo-ostia was defined as a loss of more than 60% of the original intraoperative area. The mean follow-up in our cohort was 29.2 months. Twenty-two patients were identified with increased stenosis, all of which arose within the first 12 months postsurgery. Nine of these 22 patients required revision EMLP. In all patients, the new frontal ostium narrowed at 1 year by an average of 33% (from 290 to 191 mm2, confidence interval 159–223 mm2). Restenosis and revision surgery are partly predicted by the presence of eosinophilic mucin chronic rhinosinusitis as demonstrated by logistic regression analysis. Linear regression analysis confirmed that the intraoperative frontal ostium size determines the frontal ostium area at 1 year. Conclusion: This study provides benchmarking values for the time course of the frontal ostium area after EMLP for normal wound healing and increased stenosis. On the basis of our results, patients with a higher risk for developing restenosis and of having revision surgery can be identified preoperatively and during the early postoperative period to facilitate special postoperative care.

92 citations


Journal ArticleDOI
TL;DR: The demonstration of bacterial biofilmms in this animal model of sinusitis further supports the hypotheses that biofilms may play a role in the pathogenesis of this condition.
Abstract: BackgroundBacterial biofilms have been shown in chronic diseases such as cystic fibrosis, cholesteatoma, and otitis media with effusion. Recently, their detection on the mucosal tissue of sinusitis patients has implicated them in the pathogenesis of this condition. We present an animal model using sheep experimentally infected with Staphylococcus aureus to study the possible association between biofilm and sinusitis.MethodsTwenty-four sheep underwent bilateral endoscopic sinus surgery to identify their frontal ostia. The frontal sinuses were treated in one of the following ways according to preoperative randomization: (1) ostium left patent, (2) ostium left patent and bacteria instilled, (3) ostium occluded, or (4) ostium occluded and bacteria instilled. The frontal mucosa was harvested at day 7 and examined for biofilm presence using confocal scanning laser microscopy (CSLM) as well as scanning electron microscopy (SEM) and transmission electron microscopy (TEM).ResultsAll three modalities showed differe...

92 citations


Journal ArticleDOI
TL;DR: Thin-section thoracic computed tomography demonstrates a greater variability of pulmonary venous drainage than previously described, and there is more variability of the right lung venous draining compared to the left lung.

65 citations


Journal ArticleDOI
TL;DR: PDA occlusion in dogs with the ACDO is straightforward and extremely effective across a wide range of body weights, somatotypes, MDDs, and ductal morphologies.

56 citations


Journal ArticleDOI
TL;DR: The culotte technique yields a better immediate angiographic result at the SB ostium, and, using drug-eluting stents, a better clinical outcome at 9 months, than the T-stenting technique.

50 citations


Journal ArticleDOI
TL;DR: The case of a 52-year-old woman in whom an endoscopic technique was used to remove a dental implant that had been displaced into the maxillary sinus, and the foreign body was removed through the widened ostium.
Abstract: Ear nose and throat surgeons use endoscopic operations on the sinuses not only for chronic paranasal sinusitis but also for other operations. We report the case of a 52-year-old woman in whom we used an endoscopic technique to remove a dental implant that had been displaced into the maxillary sinus. We approached the sinus through the natural ostium, and the foreign body was removed through the widened ostium.

50 citations


Journal ArticleDOI
TL;DR: The feasibility of safely deploying this first‐generation petal stent was demonstrated in selected patients with challenging coronary bifurcation lesions and is a promising platform for drug delivery, with unique scaffolding of the side‐branch ostium.
Abstract: The aim of this first-in-human study was to evaluate the feasibility and safety of the novel AST petal side-access bifurcation stent. Outcomes following percutaneous coronary intervention for bifurcations remain inferior to those of nonbifurcated lesions. Even with drug-eluting stents, restenosis occurs especially at the side-branch (SB) ostium. The petal stent uniquely deploys strut elements into the SB, supporting the ostium and carina. The primary endpoint of this 13-patient prospective registry was in-hospital major adverse cardiac events (MACE). Secondary end points included acute minimum lumen diameter (MLD) at the SB ostium, lesion success, device success, procedural success, 30-day MACE, and 4-month SB ostial MLD. The study lesion was successfully treated in 13 patients with the study stent being successfully implanted in 12. Target lesions were left anterior descending coronary artery in nine subjects, left circumflex in three, and right coronary artery in one. In-hospital MACE were limited to two non-Q-wave myocardial infarctions. In-stent main branch MLD increased from a mean of 0.63 ± 0.45 mm to 2.61 ± 0.47 mm at the index procedure and for this initial bare metal version of the stent, 4-month mean MLD measured 1.02 ± 0.42mm and there was target vessel revascularization on two patients. The feasibility of safely deploying this first-generation petal stent was demonstrated in selected patients with challenging coronary bifurcation lesions. It is a promising platform for drug delivery, with unique scaffolding of the side-branch ostium. © 2007 Wiley-Liss, Inc.

46 citations


Journal ArticleDOI
TL;DR: The results indicate that there is variability in the coronary arterial arrangement of the laboratory mouse, and care should be taken when analysing coronary phenotypes of mutant mouse models.
Abstract: There are few detailed descriptions of the coronary arterial patterns in the mouse Some recent reports on coronary anomalies in mutant mouse models have uncovered the importance of several genes (ie iv and connexin43) in coronary morphogenesis These mutations spontaneously appeared (iv) or were generated (connexin43) in a C57BL/6 background, which is widely used for the development of mutant mice We have studied the origin and course of the main coronary arteries of two C57BL/6 mouse strains Unusual anatomical coronary arterial patterns were found, including: solitary ostium in aorta, accessory ostium, high take-off, aortic intramural course, slit-like ostium, sinus-like ostium and origin of a septal artery from the left coronary artery In humans, some of these conditions are clinically relevant Most of these patterns, which differ from those observed in wild mice and Swiss albino mice, coincide with those previously found in iv/iv and connexin43 knockout mice The results indicate that there is variability in the coronary arterial arrangement of the laboratory mouse Care should be taken when analysing coronary phenotypes of mutant mouse models

44 citations


Journal ArticleDOI
01 Oct 2007-Europace
TL;DR: The anatomic relations of the human left atrial oblique vein (Marshall vein), particularly of its ostium opening into the coronary sinus, are studied in order to guide ablation procedures related to that vein.
Abstract: Aims Our objective was to study the anatomic relations of the human left atrial oblique vein (Marshall vein), particularly of its ostium opening into the coronary sinus, in order to guide ablation procedures related to that vein. Methods and results The study was carried out in 23 heart-specimens (mean weight 446+ 204 g) of individuals whose mean ages were 43+ 21 years, 20 males. The coronary sinus was opened longitudinally, exposing the ostium of the tributary veins; the Vieussens valve was looked for, as well as its relationship to the left atrial oblique vein. The diameters of the left atrial oblique vein and the coronary sinus ostia were measured and the distance between them was determined. The left atrial oblique vein could be identified in 20 (87%) of the hearts, while the Vieussens valve was present in 17 (74%) of the specimens (in 16 of which the left atrial oblique vein was identified). In such condition, the vein was adjacent to the Vieussens valve and proximally positioned relative to the coronary sinus ostium in most of them (14/16 cases). The mean diameters of the left atrial oblique vein and of the coronary sinus ostia were, respectively, 1.23+ 0.38 and 8.22+ 1.88 mm. The mean distance between both ostia was 30.9+ 10.2 mm. Conclusion When present, the left atrial oblique vein can be easily recognized, adjacent to the Vieussens valve. The mean distance between the coronary sinus opening and left atrial oblique vein ostium was around 30 mm, independently of the heart weight and the presence of cardiomegaly.

Journal ArticleDOI
TL;DR: Overlap of the LAD stent over, as opposed to under, theLCX stent was associated with close apposition of the stent to the vessel on the myocardial side, at the ostium of the LCX artery, where atherosclerotic plaques are likely to be present.
Abstract: Background: Crush stenting with drug-eluting stents is used to treat left main coronary artery (LMCA) bifurcations. However, the rate of restenosis at the left circumflex (LCX) artery ostium is high. The impact of the three-dimensional (3D) structure of LMCA bifurcation on the outcome of crush stenting with respect to restenosis has not been described. Objectives: This study examined the stent expansion, deformity, overlapping, and apposition after crush stenting of LMCA bifurcations. Methods: Bare metal stents were crushed at LMCA bifurcations in a 3D model that reproduced actual angles, such that the stent deployed from the LMCA to the left anterior descending (LAD) artery crushed the stent deployed from the LMCA to the LCX, followed by kissing balloon inflation. The stents were inspected under fluoroscopy and endoscopy. The effect of the bifurcation angle on stent expansion was also examined. Results: In the 3D model, one stent overlapped the other in the distal LMCA, in contrast to the nearly parallel position of the stents observed in a separate two-dimensional model. When the LAD stent overlapped the LCX stent, the latter was crushed on the myocardial side of the vessel, and an unstented segment was observed on the nonmyocardial side, at the LCX ostium. When the overlap was reversed, the LCX stent was crushed on the nonmyocardial side and an unstented segment was observed on the myocardial side. A narrow LMCA–LCX angle was associated with less expansion of the LCX stent at the ostium than more distally, and with a higher likelihood of incomplete stent apposition. Conclusions: Overlap of the LAD stent over, as opposed to under, the LCX stent was associated with close apposition of the stent to the vessel on the myocardial side, at the ostium of the LCX artery, where atherosclerotic plaques are likely to be present. The spatial plaque burden and bifurcation angle should be closely examined before crush stenting, and segments should not be left unstented over large plaques. © 2006 Wiley-Liss, Inc.

Journal ArticleDOI
TL;DR: Atrial macroreentry tachycardia in patients without obvious structural heart disease or previous surgical or catheter intervention has not been characterized in detail.
Abstract: Introduction: Atrial macroreentry tachycardia (AMRT) in patients without obvious structural heart disease or previous surgical or catheter intervention has not been characterized in detail. Methods and Results: Electroanatomical mapping and ablation of right or left AMRT were performed in 33 patients. Right atrial central conduction obstacle was formed by an electrically silent area (ESA) in 15 (68%) patients and by a line of double potentials (DPs) in seven (32%) patients. Left atrial ESAs were found in all 11 patients with the left AMRT. Reentry circuit was reconstructed in 19 (86%) patients with right AMRT and seven (64%) patients with left AMRT. Of the ESA-related right AMRT, eight (50%) were double-loop reentry circuits utilizing a narrow critical isthmus within the ESA and eight (50%) were single-loop reentry circuits with a critical isthmus bounded by ESA and either ostium of the vena cava. Single-loop DP-related AMRTs had the critical isthmus between the DP line and the ostium of the inferior vena cava (IVC). Left AMRTs included a variety of single-, double-, or triple-loop reentry circuits and their critical isthmuses. During the 37 ± 15 month follow-up, atrial tachyarrhythmia-free clinical outcome was achieved in 21 (95%) patients (18 patients, 82%, without antiarrhythmic drugs) with the right AMRT and in nine (82%) patients (six patients, 55%, without antiarrhythmic drugs) with the left AMRT. Conclusion: The majority of right and left AMRTs were related to the presence of ESA. Ablation can be successful with a favorable risk of atrial tachyarrhythmia recurrence.

Patent
30 Apr 2007
TL;DR: In this article, the authors propose a method for measuring the diameter of a target ostium by comparing the length, diameter and circumference of the portion of the distal end portion of a measuring device adjacent to or within the target ostiam.
Abstract: Devices and methods for accurately determining the size of an ostium of a patient and in particular sinus ostium. Methods for measuring a target ostium comprise inserting the distal end portion of an ostium measuring device into a patient, locating the target ostium with the measuring device, positioning the distal end portion of the measuring device appropriately adjacent to or into the target ostium and determining the diameter(s) of the target ostium by comparing the length, diameter and/or the circumference of the portion of the distal end portion of the measuring device adjacent to or within the target ostium.

Patent
18 Oct 2007
TL;DR: In this paper, an ostial stent positioner with a wire for most of its length and having a short cylinder with a longitudinal slit and expandable legs situated at the positioner's distal end is described.
Abstract: Disclosed is an ostial stent positioner that has the form of a wire for most of its length and having a short cylinder with a longitudinal slit and expandable legs situated at the positioner's distal end. The slit cylinder with its attached wire acts as an introducer sheath to introduce a stent delivery system with a stent into the artery that is to be stented. A second aspect of the present invention is a method for accurately placing a stent at the ostium of an artery that would have an ostial stenosis. Examples of such arteries that have ostial stenoses are the right and left main coronary arteries, a saphenous vein graft as used in coronary bypass surgery and the renal arteries. Also disclosed are designs for the slit cylinder that provides a variable diameter so as to fit snugly within guiding catheters having different inside diameters.

Journal ArticleDOI
TL;DR: Multidetector-row computed tomography (MDCT) identified double right coronary artery and it is thought to be useful to distinguish this variation from a large right ventricular branch.

Journal ArticleDOI
TL;DR: The aim of this intravascular ultrasound (IVUS) study was to assess the efficacy of the AXXESS Plus stent system for the treatment of bifurcation coronary lesions.
Abstract: Objective: The aim of this intravascular ultrasound (IVUS) study was to assess the efficacy of the AXXESS Plus stent system for the treatment of bifurcation coronary lesions. Background: The AXXESS Plus is a novel bifurcation drug-eluting stent, comprised of a self-expanding flare-shaped stent platform and bioabsorbable polymer coating that releases Biolimus A9. Methods: Data were obtained from the AXXESS PLUS trial, a prospective, multicenter, nonrandomized, single-arm study to evaluate safety and efficacy. Six-month follow-up IVUS analysis was available in 49 cases. Volumetric analysis using Simpson's method within the AXXESS stent, and cross-sectional analysis at the ostium of main branch and/or side branch was performed. Impact of bifurcation angle on stent expansion at the carina was also evaluated. Results: Within the AXXESS stent, neointimal volume obstruction percentage was 2.3% ± 2.2%, with a minimum lumen area of 7.9 ± 2.6 mm2. Lumen area was 5.2 ± 1.7 mm2 at main branch ostium, and 4.0 ± 1.5 mm2 at side branch ostium. In two cases, incomplete stent apposition was observed at the proximal edge of the AXXESS stent. In one case, a gap between the AXXESS stent and an additional stent was observed. Greater bifurcation angle inversely correlated with smaller stent area at side branch ostium (r = −0.54, P = 0.03) but not at main branch ostium (r = −0.2, P = 0.29). Conclusions: This novel self-expanding, drug-eluting bifurcation stent demonstrated effective lesion coverage along with significant neointimal suppression equivalent to current generation balloon-expandable drug-eluting stent technology. © 2007 Wiley-Liss, Inc.

Journal ArticleDOI
TL;DR: This study determined the dimensions, morphology and anatomic variations of the left main coronary artery (LMCA) in normal participants, on multidetector computed tomography, and found significant correlation was found between LMCA cross-sectional area and body weight, height and BSA.
Abstract: Objectives The aim of our study was to determine the dimensions, morphology and anatomic variations of the left main coronary artery (LMCA) in normal participants, on multidetector computed tomography. Background Accurate imaging of LMCA dimensions and configuration is crucial to avoid misdiagnosis of LMCA disease. Materials and methods Seventy morphologically normal LMCAs of 70 participants were carefully selected from among 600 consecutive coronary computed tomography angiography studies performed in our institute. LMCA cross-sectional diameters and areas were obtained at three points of each vessel: ostium, midvessel and distal. The length, cross-sectional shape, three-dimensional (3D) morphology and position of origin were studied. Influences of age, body weight, height and body surface area (BSA) on LMCA dimensions were evaluated. Results Different dimensions in each measured point of the LMCA were detected. Cross-sectional elliptic shape at ostium, mid-LMCA and distal LMCA was found in 66/70 (94%), 51/70 (73%) and 54/70 (77%) of the participants, respectively. On the basis of the 3D presentation, four types of LMCA were identified: biconcave-shape appearance (type 1), tapering morphology (type 2), combined morphology (type 3) and funnel-shape appearance (type 4). Fifty-two of the 70 participants had an LMCA orifice originating in the middle third of the aortic sinus, 15/70 in the posterior third and 3/70 in the anterior third. In men, significant correlation was found between LMCA cross-sectional area and body weight, height and BSA. In women, no correlation was found regarding body weight, height and BSA. Conclusion LMCA is not a simple straight tube but usually has various anatomical configurations, variable dimensions and cross-sectional shapes. Ostial angulation is a normal variant usually associated with the posterior position of the LMCA orifice of origin in the aortic sinus.

Journal ArticleDOI
TL;DR: MDCT imaging identifies structures adjacent to the LA, which could be affected by ablation, and identifies anatomic structures that could be vulnerable during ablation and detect unusual pathology that can affect the treatment plan.
Abstract: Increasing use of catheter ablation in the left atrium (LA) requires understanding of substrate anatomy, especially with regard to potential damage to adjacent structures. We reviewed multidetector helical computed tomography (MDCT) imaging on 42 subjects, 26 imaged before planned LA ablation for atrial fibrillation (AF), and 16 without AF. LA volume and dimensions were larger in patients with AF (p < 0.05) and the spine and aorta (Ao) impressed the LA more frequently in the AF group. The esophagus (Eo) was the predominant feature on the posterior LA wall, contacting it in all patients. The Ao was in contact with the LA body or the left inferior pulmonary vein (PV) in 32 (76%) of 42 cases, and in 10 it ran along an indentation on the posterior aspect of the LA. The coronary sinus was adjacent to LA ablation sites, the azygos vein was rarely adjacent to those sites, and the left bronchus abutted the PV ostium but not the LA. Two patients had findings that directly impacted the ablation procedure: one patient had a dilated fluid filled Eo with esophageal stricture and underwent nasogastric decompression before ablation, and one was discovered to have an anomalous PV and underwent surgical repair. MDCT imaging identifies structures adjacent to the LA, which could be affected by ablation. Posterior LA topography can be influenced by the position of the Ao or by the proximity of the spine. Preprocedural imaging can characterize anatomic structures that could be vulnerable during ablation, and detect unusual pathology that can affect the treatment plan.

Journal ArticleDOI
TL;DR: BCs may be used as adjunctive instrumentation for endoscopic sinus dissection without fluoroscopy for frontal recess dissection and this strategy warrants additional technical and clinical development.
Abstract: BackgroundRecently, balloon catheter (BC) dilatation of paranasal sinus ostia has been introduced. In this procedure, a balloon-tipped catheter is placed across a sinus ostium over a flexible wire under fluoroscopic guidance, and inflation of the balloon enlarges the ostium. Some rhinologists have criticized this procedure for its failure to remove tissue and bone, especially in the setting of sinonasal polyposis. This project seeks to develop strategies for incorporating BC technology into standard functional endoscopic sinus surgery procedures.MethodsEndoscopic sinus dissection of three human cadaveric heads was performed with conventional instruments supplemented by lacrimal duct BCs (LacriCATH; Quest Medical, Allen, TX). No fluoroscopy was used. Each dissection was videotaped for later review.ResultsFor frontal recess dissection, these steps were performed under endoscopic visualization: (1) passage of the BC between frontal recess partitions, (2) BC inflation, and (3) removal of fractured frontal rec...

Journal ArticleDOI
TL;DR: A patient with a ruptured IIA aneurysm in the interventional radiology suite was treated with embolization of the side-branch of the IIA and placement of a covered stent in the ipsilateral common and external iliac arteries.
Abstract: Ruptured aneurysms of the internal iliac artery (IIA) are rare and challenging to treat surgically. Due to their anatomic location they are difficult to operate on and perioperative morbidity is high. An endovascular approach can be helpful. We recently treated a patient with a ruptured IIA aneurysm in the interventional radiology suite with embolization of the side-branch of the IIA and placement of a covered stent in the ipsilateral common and external iliac arteries. A suitable stent-graft was not available initially and had to be brought in from elsewhere. An angioplasty balloon was temporarily placed across the ostium of the IIA to obtain hemostasis. Two hours later, the procedure was finished by placing the stent-graft.

Journal ArticleDOI
TL;DR: Various double‐stent techniques using drug‐eluting stents have been proposed to treat the left main coronary artery (LMCA) bifurcation, but use of these techniques is frequently associated with focal restenosis at the ostium of the left circumflex coronary arteries (LCX).
Abstract: Background: Various double-stent techniques using drug-eluting stents have been proposed to treat the left main coronary artery (LMCA) bifurcation. However, use of these techniques is frequently associated with focal restenosis at the ostium of the left circumflex coronary artery (LCX). Objectives: To examine the results of double-stent techniques, using a silicon model of the LMCA bifurcation and three-dimensional (3D) reconstruction images created with micro-focus X-ray computed tomography (MFCT). Methods: Crush, kissing, and modified T stentings were performed with bare metal stents in a LMCA bifurcation model. The stents were then inspected using MFCT at a minimal resolution of 0.06 mm. Results: Gaps in stent apposition to the vessel were observed at the site of stent overlap in the distal LMCA with all stenting techniques. In crush stenting, when the left anterior descending artery stent overlapped the LCX stent, the latter was crushed on the myocardial side of the vessel, and a gap was observed on the nonmyocardial side, at the LCX ostium. When the overlap was reversed, the LCX stent was crushed on the nonmyocardial side and a gap was observed on the myocardial side. In the case of kissing stents, stent overlap created a gap beneath the overlapped portion of the stents. In modified T-stenting, correct positioning of the LCX stent was difficult and MFCT imaging revealed a nonmyocardial gap. Conclusions: Close apposition of the stent to the vessel at the ostium of the LCX is difficult to achieve at the LMCA bifurcation, regardless of which double-stent technique is employed, due to the site's wide bifurcation angle and complex 3D structure. The distribution of plaque and the bifurcation angle should be considered before double-stent deployment, to avoid leaving a gap over significant plaques. © 2007 Wiley-Liss, Inc.

Journal ArticleDOI
TL;DR: It is demonstrated that up to three focal ATs can be successfully ablated at a single procedure without recurrence or development of other atrial arrhythmias in long-term follow-up.

Patent
18 Dec 2007
TL;DR: In this paper, a system for unobstructed visualization and ablation of the pulmonary veins is described, which includes a deployment catheter and an attached imaging hood deployable into an expanded configuration as well as one or more expandable anchors.
Abstract: Systems and methods for unobstructed, visualization and ablation, particularly of the pulmonary veins, are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration as well as one or more expandable anchors which are temporarily securable within a respective pulmonary vein while allowing blood flow to pass through the anchor unimpeded. With the one or more non-impeding anchors secured within a respective pulmonary vein, ablation of the tissue surrounding the ostium or several ostia may be effected with the catheter while the tissue is under direct visualization.

Journal Article
TL;DR: An 83-year-old Indian man who presented with AMI and was subsequently found to have CSSS is described, with resolution of myocardial blood flow steal and anterior ischaemia.
Abstract: The coronary subclavian steal syndrome (CSSS) leading to an acute myocardial infarction (AMI) post-coronary bypass is a rare occurrence. We describe an 83-year-old Indian man who presented with AMI and was subsequently found to have CSSS. The patient had severe stenosis of his left subclavian artery ostium with retrograde flow up his left internal mammary artery graft. Angiographical steal from the left anterior descending artery was demonstrated during coronary angiogram and was thought to be the main contributing cause of his AMI. Percutaneous transfemoral angioplasty and stent implantation was performed to the left subclavian artery, with resolution of myocardial blood flow steal and anterior ischaemia.

Journal ArticleDOI
TL;DR: SES demonstrated a high rate of successful implantation with few complications, and mid-term outcomes were excellent, and sirolimus-eluting stent approved for use in Japan.
Abstract: Background The sirolimus-eluting stent (SES) is currently the sole drug-coated stent approved for use in Japan, but there are few reports on its safety and outcomes in Japan. Methods and Results From May 2004 to February 2005, a total of 297 patients with 402 lesions were treated with SES at 6 hospitals in the Kansai district. Follow-up angiography was performed in 82% of the patients and 80% of the lesions at 182±35 days after stenting. Coronary stenosis was evaluated using quantitative coronary angiography. Clinical and angiographic data were analyzed. Minimum lesion diameter was 0.75±0.52 mm and the reference diameter was 2.81±0.47 mm before stenting. The SES successfully dilated 99.5% of the lesions with few major adverse cardiac events. Restenosis occurred in 4.0% and the target lesion revascularization rate was 3.7%. Restenosis correlated with chronic hemodialysis, calcification, occlusion, ostial lesions, lesions kinked >45 degrees, right coronary artery (RCA) lesions and lesions at the ostium of the RCA. Conclusion SES demonstrated a high rate of successful implantation with few complications, and mid-term outcomes were excellent. Patients with lesions at the ostium of the RCA or under chronic hemodialysis developed restenosis. (Circ J 2007; 71: 15 - 19)

Journal ArticleDOI
TL;DR: Laroscopic debranching of visceral vessels extends the indications of EVAR with a case of thoraco-abdominal aneurysm extending from the descending thoracic aorta to the level of coeliac artery.

Journal ArticleDOI
TL;DR: It is observed that calcification at the renal artery ostium may influence the development of atherosclerotic effects as a direct relationship between the calcification and ostial diameter.
Abstract: Purpose: To investigate the morphological effects of suprarenal fixation of aortic stent-grafts on the renal artery ostia (RaO) by analysis of suprarenal stent wire distribution and vascular calcification across the RaO using virtual intravascular endoscopy (VIE). Methods: Fourteen consecutive patients (11 men; mean age 75 years) from a single institution were studied following endovascular aortic aneurysm repair (EVAR) using the Zenith endograft system from September 1999 to March 2002. Imaging assessment included computed tomographic (CT) measurement of renal artery intraluminal ostial diameter and quantification and analysis of uncovered stent struts across the RaO and radiological determination of RaO calcification. Morphological changes following EVAR at 3 time points (before and within 1 week after stent-grafting, and at the most recent follow-up) were compared for each patient to determine whether suprarenal stent struts or RaO calcification affected intraluminal ostial diameter. Renal function was assessed by temporal measurements of serum creatinine concentration and creatinine clearance. Results: The renal ostium was distorted to variable degrees in all cases at a mean follow-up of 41 +/-6.6 months. An increase in ostial diameter was identified in most patients if the right RaO was calcified when comparing the 1-week postoperative and most recent follow-up CT images (p 0.05). Renal function was not significantly affected. Conclusion: Patients undergoing suprarenal fixation of aortic stent-grafts experienced morphological changes of the RaO to a variable extent at midterm follow-up. Although the presence of stent struts did not significantly affect dimensional changes, we observed that calcification at the renal artery ostium may influence the development of atherosclerotic effects as a direct relationship between the calcification and ostial diameter. Future studies utilizing VIE to determine the long-term safety of this technique in these particular patients requires investigation.

Journal ArticleDOI
TL;DR: A 75-year-old man had routine phacoemulsification cataract extraction with posterior chamber intraocular lens implantation in the left eye using a temporal corneal incision and inferior paracentesis, and at the 6-week assessment, a cilium was noted to have penetrated the external ostium of theParacentesis.
Abstract: A 75-year-old man had routine phacoemulsification cataract extraction with posterior chamber intraocular lens implantation in the left eye using a temporal corneal incision and inferior paracentesis. Examinations at 1 day and 1 week were unremarkable; however, at the 6-week assessment, a cilium was noted to have penetrated the external ostium of the paracentesis, with the proximal (follicle) end abutting the internal ostium of the wound. While the cilium was removed without incident, this chance finding may aid our understanding of how intraocular cilia are occasionally discovered following routine small-incision sutureless cataract surgery.

Journal Article
TL;DR: A multielectrode basket catheter (MBC) is also useful for PVI because of some advantages; as discussed by the authors provides some information about the PV anatomy on the fluoroscopic image, an MBC can utilize the non-fluoroscopic navigation system, and the MBC enables the direct three-dimensional mapping around the PV ostium and antrum.
Abstract: Pulmonary vein (PV) isolation (PVI) techniques have evolved as a curative treatment of atrial fibrillation (AF) since PVI guided by circumferential mapping with a circular catheter was initially proposed. A multielectrode basket catheter (MBC) is also useful for PVI because of some advantages; (1) an MBC provides some information about the PV anatomy on the fluoroscopic image, (2) an MBC can utilize the non-fluoroscopic navigation system, (3) an MBC enables the direct three-dimensional mapping around the PV ostium and antrum, (4) the distal electrodes of the MBC can be used to monitor some activation changes within the PV in real time and thereby indicate the effects of ablation at the ostium and antrum as radiofrequency lesions are created. PVI with an MBC is an effective and safe procedure to cure AF by integrating the PV anatomy and electrophysiology in combination with a non-fluoroscopic three-dimensional navigation system for the ablation catheter.