Showing papers on "Surgical oncology published in 1982"
Book•
01 Jan 1982
TL;DR: Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays Section 5. Cytogenetics Section 6. Bioinformatics Genomics and Proteomics Molecular Targets in oncology.
Abstract: Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays Section 5. Cytogenetics Section 6. Bioinformatics Genomics and Proteomics Molecular Targets in Oncology Section 1. Signal transduction systems Section 2. Cell cycle Section 3. Apoptosis Section 4. Telomerase Invasion and Metastases Angiogenesis Cancer Immunology Part II: Principles of Oncology Etiology of Cancer: Viruses Section 1. RNA Viruses Section 2. DNA Viruses Etiology of Cancer: Chemical Factors Etiology of Cancer: Tobacco Etiology of Cancer: Physical Factors Epidemiology of Cancer Section 1. Epidemiologic Methods Section 2. Cancer Statistics Principles of Surgical Oncology Section 1. General Issues Section 2. Laparascopic Surgery Principles of Radiation Oncology Principles of Medical Oncology Pharmacology of Cancer Chemotherapy Section 2. Pharmocokinetics Section 3. Pharmacogenomics Section 4. Alkylating Agents Section 5. Cisplatin and its Analogues Section 6. Antimetabolites Section 7. Topoisomerase Interactive Agents Section 8. Antimicrotubule Agents Section 9. Miscellaneous Chemotherapeutic Agents Pharmacology of Cancer Biotherapeutics Section 1. Interferon Section 2. Interleukin 2 Section 3. Histone deacetylase inhibitors as differentiation agents Section 4. Monoclonal Antibodies Pharmacology of Endocrine Manipulation Design and Analysis of Clinical Trials Part III: Practice of Oncology Cancer Prevention: Preventing Tobacco-Related Cancers Cancer Prevention: Diet and Chemopreventive Agents Section 1. Dietary fat Section 2. Dietary Fiber Section 3. Dietary fruits and vegetables: naturally occurring anticarcinogens Section 4. Retinoids, carotenoids and micronutrients Section 5. Dietary Carcinogens Section 6. Cyclo-oxygenase inhibitors Section 7. Physical Activity and Body Weight Cancer Prevention: Role of Surgery in Cancer Prevention Cancer Screening Advanced Molecular Diagnostics Advanced Imaging Methods Section 1. Functional and Metabolic Imaging Section 2. Interventional Radiology Cancer Diagnosis: Endoscopy Section 1. Gastrointestinal endoscopy Section 2. Respiratory Tract Cancer of the Head and Neck Section 1. Molecular Biology of Head and Neck Tumors Section 2. Treatment of Head and Neck Cancers Section 3. Rehabilitation after Treatment for Head Cancer of the Lung Section 1. Molecular Biology of Lung Cancer Section 2. Non-small Cell Lung Cancer Section 3. Small Cell Lung Cancer Neoplasms of the Mediastinum Cancers of the Gastrointestinal Tract
9,166 citations
TL;DR: It is concluded that resection is definitely indicated in patients with T1 N0 M0 lesions and probably indicated in those with T 1 N1 M0 or T2 N0M0 lesions, and primary surgical resections is contraindicated in Patients with any other TNM category.
223 citations
TL;DR: There were minimal complications associated with the use of ureteral catheters in routine use and unrecognized injuries (except ischemia) did not occur.
Abstract: Injury to the ureters is a serious complication of colonic and rectal surgery. The experience of the authors with routine use of ureteral catheters to minimize this complication is reviewed. It was found that there are minimal complications associated with their use. Injuries to the ureters were not completely avoided. However, unrecognized injuries (except ischemia) did not occur.
78 citations
TL;DR: A statistically significant poorer prognosis was observed in patients with left-sided tumors, with an emergency presentation and with a duration of symptoms shorter than six months, in patients operated upon for colorectal cancer.
Abstract: Four prognostic factors,i.e., site of the tumors, mode of presentation, duration of symptoms, and pathologic staging, were correlated to the results of surgical treatment,i.e., curative resectability, postoperative complications and mortality, and five-year survival, in 161 patients operated upon for colorectal cancer.
40 citations
TL;DR: Clinical conditions, unrelated to trophoblastic diseases, associated with an increased level of serum human chorionic gonadotropin (hCG) are reviewed.
Abstract: A case of adenocarcinoma of the sigmoid colon with focal choriocarcinoma metaplasia is documented. Pathogenesis is briefly discussed, and clinical conditions, unrelated to trophoblastic diseases, associated with an increased level of serum human chorionic gonadotropin (hCG) are reviewed.
36 citations
TL;DR: Patients with polyposis coli have an increased risk of developing periampullary malignancies, particularly if duodenal polyps are present, and periodic follow-up radiologic studies of the upper gastrointestinal tract are necessary.
Abstract: Patients with polyposis coli have an increased risk of developing periampullary malignancies, particularly if duodenal polyps are present. Since periampullary neoplasms occur, on the average, 15 years following the initial diagnosis of colonic polyps, periodic follow-up radiologic studies of the upper gastrointestinal tract are necessary in the management of polyposis coli.
32 citations
TL;DR: A case of sarcoidosis with involvement of the rectum is described and the findings raise the question of the incidence of gastrointestinal involvement in this disease.
Abstract: A case of sarcoidosis with involvement of the rectum is described. This is the third documented report of “silent” rectal sarcoidosis. The findings described in the three cases raise the question of the incidence of gastrointestinal involvement in this disease.
19 citations
TL;DR: Analysis of the evolution of the currently used Dukes' system for post-surgical staging of carcinoma of the rectum concluded that no further modification is likely to improve understanding of a patient's disease or prognosis.
Abstract: Analysis is made of the evolution of the currently used Dukes' system for post-surgical staging of carcinoma of the rectum. It is concluded that no further modification is likely to improve understanding of a patient's disease or prognosis.
17 citations
16 citations
15 citations
TL;DR: In this article, the 17th case of free perforation of the colon in Crohn's disease is described, and previous reports are reviewed and discussed in detail in detail.
Abstract: Free perforation of the colon in Crohn's disease is a very rare complication. An additional case, the 17th in the literature, is described, and previous reports are reviewed.
TL;DR: It is suggested that selected patients who have had adequate bowel preparation have minimal risks associated with additional intra-abdominal surgery performed at the time of colectomy.
Abstract: In a series of 242 patients who underwent additional intra-abdominal surgery at the time of colectomy, there were two deaths (0.8 per cent) and five (2 per cent) complications. This experience suggests that selected patients who have had adequate bowel preparation have minimal risks associated with additional intra-abdominal surgery performed at the time of colectomy.
TL;DR: In attempts to predict the recurrence of gastric cancer, postoperative changes in serum carcinoembryonic antigen (CEA) levels are monitored by radioimmunoassay and recurrence was predicted in 17 out of 34 patients and in 12 out of 17 patients there was a metastasis to the liver.
Abstract: In attempts to predict the recurrence of gastric cancer, postoperative changes in serum carcinoembryonic antigen (CEA) levels are monitored in our clinic by radioimmunoassay (Dainabot, Japan). Recurrences are suspected when serum CEA levels are 4 ng/ml, in the postoperative period. Out of 34 patients in whom there were increases in serum CEA, 18 were confirmed to have a recurrence and 15 of these 18 patients were assessed accurately by serial postoperative levels of CEA, two patients died of a recurrence after elevation of serum CEA levels. Thus, recurrence was predicted in 17 out of 34 patients (50 per cent) and in 12 out of 17 patients there was a metastasis to the liver. In 14 out of 34 patients there are no signs of recurrence 9 to 25 months after serum CEA elevations.
TL;DR: A case of acute colitis as the initial manifestation of the hemolytic-uremic syndrome in an 8-year-old boy is described and the incidence, significance, and therapeutic implications in this disorder are discussed.
Abstract: A case of acute colitis as the initial manifestation of the hemolytic-uremic syndrome in an 8-year-old boy is described. The incidence, significance, and therapeutic implications of gastrointestinal tract complications in this disorder, which may simulate infectious or inflammatory bowel disease, are discussed.
TL;DR: In this paper, a case of massive hemorrhage from a cecal ulcer is presented, and the literature is reviewed, emphasizing the role of angiographic demonstration of the lesion, if angiography is readily available.
Abstract: Massive gastrointestinal hemorrhage secondary to benign cecal ulceration is a rare occurrence. The diagnosis of bleeding from this benign condition is rerely entertained and is often a finding on a pathologic examination. A case of massive hemorrhage from a cecal ulcer is presented, and the literature is reviewed. The role of angiographic demonstration of the lesion, if angiography is readily available, is emphasized, but surgery is the definitive therapy.
TL;DR: Prostaglandin F2α applied directly in quantities up to 400 μ g had no clinical effect on the emptying time of the colon in patients undergoing colostomy irrigation.
Abstract: Prostaglandin F2α applied directly in quantities up to 400 μ g had no clinical effect on the emptying time of the colon in patients undergoing colostomy irrigation.
TL;DR: This case report describes a patient initially presenting with Crohn's disease of the ileum who subsequently developed ulcerative proctocolitis, and was diagnosed with both inflammatory bowel disease confirmed by histopathologic examination.
Abstract: This case report describes a patient initially presenting with Crohn's disease of the ileum who subsequently developed ulcerative proctocolitis Reports of patients with both inflammatory bowel disease confirmed by histopathologic examination are rare
TL;DR: A 52 year old woman who noticed a firm, non-tender mass in her left breast but which showed no enlargement over a two month period is treated.
Abstract: P s e u d o l y m p h o m a occurs in different organs but the occurrence of pseudolymphoma of the breast is rare and may be misdiagnosed as a case of malignant lymphoma. Though the pathological differentiation of this lesion is difficult, a careful distinction is necessary as the therapy and succeeding events vary considerably. We treated a 52 year old woman who noticed a firm, non-tender mass in her left breast but which showed no enlargement over a two month period. She never experienced nipple discharge or dull pain nor had she ever required surgical t reatment of the breast. Her menarche was at the age of 15 years and the menopause occurred at the age of 30. She had never become pregnant. Physical examination of the breast revealed a firm movable mass, 2 cm in the greatest diameter, located in the lower outer quardant of the breast. The surface of the mass was somewhat irregular and the border could be clearly defined. There was neither nipple retraction, dimpling sign nor nipple discharge in either breast. No su-
Journal Article•
TL;DR: In this paper, a 52 year old Japanese man with a malignant lymphoma in the residual stomach 16 years after a gastrectomy was surgically treated and a discussion of related literature is reported.
Abstract: We surgically treated a 52 year old Japanese man with a malignant lymphoma in the residual stomach 16 years after a gastrectomy. Our findings and a discussion of related literature are reported herein.
TL;DR: The resected colon was found to contain an additional occult carcinoma distal to the primary lesion, and the authors' recommendation, a total abdominal colectomy was performed.
Abstract: A case is reported of a 47-year-old man with a family history consistent with Cancer Family Syndrome (CFS), who manifested proximal colon carcinoma. On the authors' recommendation, with the knowledge that the colon in CFS shows an inordinate lifelong susceptibility to malignant neoplastic transformation, a total abdominal colectomy was performed. The resected colon was found to contain an additional occult carcinoma distal to the primary lesion. Knowledge of this phenomena is critical to the management of CFS
TL;DR: Surgical exc i s i on combined with radiotherapy is the treatment o f choice for EMP of the gastrointest inal tract with a high tendency toward local recurrence.
Abstract: Extramedul lary p lasmacytoma {EMP) of the smal l bowe l is a rare entity prev ious ly reported as a cause o f intestinal obstruct ion or bleeding. A case report of this d i sease entity pre sen t ing as an i l eoco l i c f istula is reported. EMP is d iagnosed by the fo l l owing criteria: 1) absence o f paraprote inemia; 2) absence o f B e n c e Jones prote inur ia ; 3) normal ske le ta l survey; and 4) n o r m a l bone marrow biopsy spec imen. Gastrointest inal p lasmacytoma often occurs as a manifestat ion of mul t ip le mye loma. EMP of the gastrointest inal tract is a rare manifestat ion of the d isease , accounting for 13 per cent o f all cases o f EMP. It is a s low-spreading , radiosens i t ive minor with a high tendency toward local recurrence . Surgical exc i s i on combined with radiotherapy is the treatment o f choice for EMP of the gastrointest inal tract. [
TL;DR: From 1965 to 1980, reoperations for residual or recurrent stones were performed on 78 out of 962 Japanese patients with cholelithiasis, and the majority of patients who required reoperation had intrahepatic stones.
Abstract: From 1965 to 1980, reoperations for residual or recurrent stones were performed on 78 out of 962 Japanese patients with cholelithiasis. The majority of patients who required reoperation had intrahepatic stones. Most of the causes of reoperation were residual stones due to incomplete removal or the non-detection of intrahepatic stones at the previous surgery. Very careful examination of the intrahepatic biliary trees should be done in patients with biliary tract diseases, because in many, the first operation was done during their youth. To remove the intrahepatic calculi completely, hepatic lobectomy should be considered as a final procedure. The causes of reoperation of common duct stones were residual in 60 per cent and recurrent in 40 per cent. Definitive surgery should be done at the first or at least the second operation to avoid irreversible hepatic disorders which have untoward effects on the prognosis. It is important not only to remove the stones but also to relieve the bile stasis in the biliary tract.