Showing papers on "Surgical wound published in 1977"
TL;DR: The preliminary results illustrate the hazards of heparin therapy and suggest that bleeding complications are more closely related to duration of therapy, age, sex, and surgical trauma than to method of administration.
221 citations
TL;DR: The application of carefully selected topical antibiotics to surgical wounds, particularly those that represent a high risk for the development of wound infection, can be expected to diminish the incidence of this complication in a significant fashion.
Abstract: • The topical use of antibiotics in surgical wounds is critically reviewed and analyzed. Thirteen experimental and 19 clinical reports are included in this review. Prospective and retrospective clinical studies have been separated. The analysis evaluated clean vs contaminated/dirty wounds, as well as the effects of various antibiotics and combinations. The conclusion reached on the basis of the experimental and clinical data is that the application of carefully selected topical antibiotics to surgical wounds, particularly those that represent a high risk for the development of wound infection, can be expected to diminish the incidence of this complication in a significant fashion. (Arch Surg112:1240-1244, 1977)
75 citations
TL;DR: A single antigenically characteristic strain of group A streptococci was recovered from the wounds of all four patients and from the anus of one surgeon who had participated in the surgery on three of the patients.
47 citations
TL;DR: A 46-year-old male who developed an Allescheria boydii infection secondary to excision of an interdigital neuroma is reported who received multiple local corticosteroid injections which may have produced local as well as systemic immunosuppression.
Abstract: This is a report of a 46-year-old male who developed an Allescheria boydii infection secondary to excision of an interdigital neuroma. Previously reported cases of infection occurred in an immunosuppressed patient and in patients on systemic corticosteroid therapy, but not associated with a surgical wound. This patient received multiple local corticosteroid injections which may have produced local as well as systemic immunosuppression. Fungal cultures were not taken for many months and thus the true etiology of the infection was not discovered until late. The importance of obtaining fungal cultures particularly in patients receiving corticosteroid therapy, either local infiltration or systemic, cannot be overemphasized.
30 citations
TL;DR: Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antib bacterial activity against E coli.
Abstract: Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antibacterial activity against E coli. Blood serum also contains heat-labile antibacterial substances, but little heat-stable activity against Staphylococcus aureus. Both blood serum and wound fluid have bacteriostatic activity against S epidermidis, and early growth of Streptococcus fecalis occurs in serum and wound fluids. The concentration or activity of antimicrobial proteins increases during the first week in the fresh wound and then decreases as the wound matures.
20 citations
TL;DR: Treating soft tissue injuries, the surgeon must employ specific therapeutic modalities that allow the wound to heal per primam without infection, on the basis of experimental studies supported by clinical experience, which is recommended.
20 citations
TL;DR: The data presented suggest that under the same in vitro conditions, blood and wound leukocytes are functionally equivalent, that tissue mobilization does not cause alteration of woundLeukocytes, and that aging of the wound does not impair the microbicidal capacity of wound Leukocytes.
Abstract: Oxygen consumption, glucose oxidation via the hexose monophosphate shunt, and superoxide production by resting and stimulated leukocytes derived from rabbit blood and from experimental rabbit wounds five to seventeen days old were measured and compared. In vitro killing of staphylococci by blood and wound leukocytes was also measured. In all of these studies there were no significant functional differences between blood and wound cells. The data presented suggest that under the same in vitro conditions, blood and wound leukocytes are functionally equivalent, that tissue mobilization does not cause alteration of wound leukocytes, and that aging of the wound does not impair the microbicidal capacity of wound leukocytes.
18 citations
TL;DR: An analysis of the geometric and mechanical factors leading to the formation of dogears at the ends of surgical wounds in the skin is presented and corrective measures are discussed.
Abstract: An analysis of the geometric and mechanical factors leading to the formation of dogears at the ends of surgical wounds in the skin is presented. Corrective measures are discussed.
15 citations
Journal Article•
TL;DR: The comparison of the two groups shows that the time-consuming aseptic method of changing and dressing surgically incised wounds 24 to 36 hours after surgery, does not cut down on the rate of wound infection and is probably unnecessary.
Abstract: At the University College Hospital, Ibadan, the conventional method of surgical wound dressing is the use of air-tight and relatively water-tight cotton-gauze-elastoplast dressing. This is usually left in place for seven to ten days unless there is evidence of wound infection, in which case the wound is inspected and redressed using the time-consuming sterile technique, in which a box of sterile instruments may have to be shared amongst about 25 surgical patients. A group of 100 patients was randomly selected and this group divided into two. In the first group, A, the surgical wounds were dressed in the usual manner and dressings left for seven to ten days unless there was any evidence of infection. In the second group, B, the wound was left undressed and "uncared" for 24 to 36 hours after surgery. The comparison of the two groups shows that the time-consuming aseptic method of changing and dressing surgically incised wounds 24 to 36 hours after surgery, does not cut down on the rate of wound infection and is probably unnecessary. This may be due to early formation of fibrin at the wound site which offers a protection against invasion of the wound by bacteria. Typhoid perforation of the terminal ileum gave rise to wound infection in all the cases (100%) in the two groups.
15 citations
TL;DR: The culturing frequency by the ward staff was so high that surveillance of infection by review of bacteriological culture records only, would give an almost equivalent degree of information concerning infection rates, which is less time consuming and also has the advantage of giving epidemiological information.
Abstract: A prevalence study concerning wound infections in the surgical service at a university hospital was made during a 7-month period. One ward was visited every week during the wound dressing rounds and samples for bacteriologic culture were taken from clinical infections. The prevalence of infection varied between 0 and 21% (median value 8.2%) for surgical wounds and between 0 and 47% (median value 5.3%) for other wounds. Staphylococcus aureus made up 16% of the bacteria isolated from surgical wounds and the Enterobacteriacae 32.6%. For other wounds Staph. aureus and the Enterobacteriacae made up 22.6% each. A comparison of the number of cultures taken by investigators and that taken by the ward showed that the culturing frequency by the ward staff was so high that surveillance of infection by review of bacteriological culture records only, would give an almost equivalent degree of information concerning infection rates. This system is less time consuming and also has the advantage of giving epidemiological information. The drawback with the system is that little or no patient data are given on the requisitions from the ward. This makes it impossible to know from what kind of infections samples are taken.
13 citations
TL;DR: Suggestions for improvement of the results such as more effective surveillance and reporting of hospital-acquired infections are proposed and a plea made for continuous vigorous epidemiological research on nosocomial infections not only in the University Teaching Hospital but also in all other hospitals in Lagos and Nigeria.
TL;DR: A case of a benign talc granuloma in a 3-year-old boy is reported.
Journal Article•
TL;DR: The healing process of cutaneous wounds has been followed with the aid of mechanical tests, autoradiographic investigation of fibroblastic reaction in the wound and method of electron microscopy and Cyclophosphamide has been found not to have any substantial effect on the favorable course of healing of the surgical wound.
Abstract: The healing process of cutaneous wounds has been followed with the aid of mechanical tests, autoradiographic investigation of fibroblastic reaction in the wound and method of electron microscopy Cyclophosphamide has been found not to have any substantial effect on the favorable course of healing of the surgical wound, hence, surgical intervention combined with postoperative administration of Cyclophosphamide does not jeopardize the healing process
TL;DR: Although the activated partial thromboplastin time shortened following the infusion, the exact physiologic mechanism whereby these concentrates bypass the need for factor VIII clotting activity is unknown.
Abstract: A hemophilliac with a factor VIII inhibitor was bleeding massively from an extensive surgical wound. After ten days of unsuccessful management by conservative measures, he was given a single infusion of prothrombin complex concentrate (Konyne). Bleeding stopped immediately and the wound healed without further recurrence of bleeding. Although the activated partial thromboplastin time shortened following the infusion, the exact physiologic mechanism whereby these concentrates bypass the need for factor VIII clotting activity is unknown.
TL;DR: Quantitative bacterial analyses of the abscesses, blood, and wounds indicate that wounds in the control group consistently became infected with 3 × 108E.
TL;DR: Although the activated partial thromboplastin time shortened following the infusion, the exact physiologic mechanism whereby these concentrates bypass the need for factor VIII clotting activity is unknown.
Abstract: A hemophiliac with a factor VIII inhibitor was bleeding massively from an extensive surgical wound. After ten days of unsuccessful management by conservative measures, he was given a single infusion of prothrombin complex concentrate (Konyne). Bleeding stopped immediately and the wound healed without further recurrence of bleeding. Although the activated partial thromboplastin time shortened following the infusion, the exact physiologic mechanism whereby these concentrates bypass the need for factor VIII clotting activity is unknown. (Arch Intern Med137:1211-1213, 1977)
TL;DR: In this paper, a 64-year-old man had vascular ingrowth of a surgical wound resulting in recurrent hyphema and pupillary block glaucoma three years after cataract extraction.
Journal Article•
TL;DR: The venous system was never impaired whereas the local lymphatic system was always damaged by surgical aggression on the arterial vessels, so the lymphatic structure encountered during the operation should be carefully ligated to counteract another dangerous complication: infection.
Abstract: As a result of the observation of oedemas of the lower extremities and lymphorrhoea in the immediate postoperative course of surgical reconstruction of the aorto-iliaco-femoro-popliteal arterial axis (and on the basis of similar cases in the literature), the participation of the lower extremity return circulation in this facet of vascular surgery has been documented. The venous system was never impaired whereas the local lymphatic system was always damaged by surgical aggression on the arterial vessels. However, the extensive anatomical lesions shown up by lymphography are not reflected in evident clinical signs; whenever oedema or lymphorrhoea of the surgical wounds are observed, these symptoms are always of slight importance and easily and quickly resolved. At long-term follow-up, no clinical evidence of impairment ot the venous and lymphatic venous return circulation was ever encountered. For prophylactic purposes the lymphatic structure encountered during the operation should be carefully ligated to counteract another dangerous complication: infection.
Journal Article•
TL;DR: The authors report a series of surgical wounds, all immediately repaired, that indicate end-to-end suture seems the first choice procedure with the best longterm results in biliary accidents, and stress the importance of prevention methods that will help to limit the risks of such operative accidents.
Abstract: The authors report a series of eleven surgical wounds, all immediately repaired. They consider the frequency of these biliary accidents to be 2% in cholecystectomies and 4% in gastrectomies. In such instances end-to-end suture seems the first choice procedure with the best longterm results. They stress the importance of prevention methods that will help to limit the risks of such operative accidents and not to overlook them, should they occur.
Journal Article•
TL;DR: In this article, the subcutaneous fat located around the tailhead of a sheep was extracted with minimal restraint of the sheep and local anesthesia and up to 1 g of fat was obtained using this surgical procedure.
Abstract: Previously reported fat biopsy techniques (either omental or subcutaneous) require extensive restraint of the animal, require anesthesia methods, are time-consuming to do, or demand much postoperative care. The biopsy technique reported in the present paper involves the subcutaneous fat located around the tailhead of sheep. With minimal restraint of the sheep and local anesthesia, up to 1 g of subcutaneous fat can be obtained using this surgical procedure. Michel clips facilitate closure of the surgical wound, making this method brief in operative time.
TL;DR: Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antib bacterial activity against E coli.
Abstract: Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antibacterial activity against E coli. Blood serum also contains heat-labile antibacterial substances, but little heat-stable activity against Staphylococcus aureus. Both blood serum and wound fluid have bacteriostatic activity against S epidermidis, and early growth of Streptococcus fecalis occurs in serum and wound fluids. The concentration or activity of antimicrobial proteins increases during the first week in the fresh wound and then decreases as the wound matures.
Journal Article•
01 Jan 1977-Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, präventive Medizin
TL;DR: In a female patient with metastasizing carcinoma S. typhimurium was identified in the laparotomy wound during a period of roughly three weeks, and Agglutinating antibodies were not detected.
Abstract: In a female patient with metastasizing carcinoma S. typhimurium was identified in the laparotomy wound during a period of roughly three weeks. Agglutinating antibodies were not detected. Pathogenetic and hygienic aspects are discussed.