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Adam F. Sander
Researcher at University of Copenhagen
Publications - 39
Citations - 1175
Adam F. Sander is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Antibody & Plasmodium falciparum. The author has an hindex of 15, co-authored 28 publications receiving 838 citations. Previous affiliations of Adam F. Sander include Copenhagen University Hospital.
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Journal ArticleDOI
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein
Ali Salanti,Thomas Mandel Clausen,Mette Ø. Agerbæk,Nader Al Nakouzi,Nader Al Nakouzi,Madeleine Dahlbäck,Htoo Zarni Oo,Htoo Zarni Oo,Sherry Lee,Tobias Gustavsson,Jamie R. Rich,Bradley John Hedberg,Yang Mao,Line Barington,Marina Ayres Pereira,Janine LoBello,Makoto Endo,Ladan Fazli,Jo Soden,Chris K. Wang,Adam F. Sander,Robert Dagil,Susan Thrane,Peter Johannes Holst,Le Meng,Francesco Favero,Glen J. Weiss,Glen J. Weiss,Morten Nielsen,Jim Freeth,Torsten O. Nielsen,Joseph Zaia,Nhan L. Tran,Jeff Trent,John Babcook,Thor G. Theander,Poul H. Sorensen,Mads Daugaard,Mads Daugaard +38 more
TL;DR: The data demonstrate how an evolutionarily refined parasite-derived protein can be exploited to target a common, but complex, malignancy-associated glycosaminoglycan modification.
Journal ArticleDOI
Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Susan Thrane,Susan Thrane,Christoph M. Janitzek,Christoph M. Janitzek,Sungwa Matondo,Mafalda Resende,Mafalda Resende,Tobias Gustavsson,Tobias Gustavsson,Willem A. de Jongh,Stine N. Clemmensen,Stine N. Clemmensen,Stine N. Clemmensen,Will Roeffen,Marga van de Vegte‑Bolmer,Geert-Jan van Gemert,Robert W. Sauerwein,John T. Schiller,Morten Nielsen,Morten Nielsen,Thor G. Theander,Thor G. Theander,Ali Salanti,Ali Salanti,Adam F. Sander,Adam F. Sander +25 more
TL;DR: The spy-VLP system constitutes a versatile and rapid method to develop highly immunogenic VLP-based vaccines and could facilitate rapid and unbiased screening of vaccine candidate antigens.
Journal ArticleDOI
Virus-like particle display of HER2 induces potent anti-cancer responses
Arianna Palladini,Susan Thrane,Christoph M. Janitzek,Jessica Pihl,Stine B. Clemmensen,Stine B. Clemmensen,Willem A. de Jongh,Thomas Mandel Clausen,Giordano Nicoletti,Lorena Landuzzi,Manuel L. Penichet,Tania Balboni,Marianna L. Ianzano,Veronica Giusti,Thor G. Theander,Morten Nielsen,Ali Salanti,Pier Luigi Lollini,Patrizia Nanni,Adam F. Sander +19 more
TL;DR: Using a novel virus-like particle (VLP) based vaccine platform, it is shown that directional, high-density display of human HER2 on the surface of VLPs, allows induction of therapeutically potent anti-HER2 autoantibody responses.
Journal ArticleDOI
Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface.
Marta Tibúrcio,Francesco Silvestrini,Lucia Bertuccini,Adam F. Sander,Adam F. Sander,Louise Turner,Louise Turner,Thomas Lavstsen,Thomas Lavstsen,Pietro Alano +9 more
TL;DR: Specific differences in molecular and cellular mechanisms of host cell remodelling and in adhesive properties are identified, leading to clearly distinct host parasite interplays in the establishment of sequestration of stage I gametocytes and of asexual trophozoites.
Journal ArticleDOI
Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates
Adam F. Sander,Ali Salanti,Thomas Lavstsen,Morten Nielsen,Pamela Magistrado,Pamela Magistrado,John Lusingu,Nicaise Tuikue Ndam,David E. Arnot +8 more
TL;DR: In this paper, the var2csa gene encodes a Plasmodium falciparum adhesion receptor which binds chondroitin sulfate A (CSA).