Alex Mabou Tagne

TL;DR: More rigorously designed investigations are needed to recommend the whole plant or its active ingredients as a medication, and should focus on understanding the multi-target network pharmacology of the plant, clarifying the effective doses as well as identifying the potential interactions with prescribed drugs or other chemicals.

TL;DR: Assessment of the effects of CM5, a novel Cannabis sativa L. extract standardized in 5% cannabidiol (CBD), on human PMN functions, including cell migration, oxidative metabolism and production of tumour necrosis factor (TNF)-α shows that both CM5 and CBD inhibit PMN migration, ROS and TNF-α production, indicating that CBD may be the main item responsible for the effectsof CM5.

TL;DR: Although preclinical studies suggest the potential effectiveness of CBD in viral diseases such as hepatitis C and Kaposi sarcoma, clinical evidence is still lacking and anecdotal experiences of CBD use retrieved on the Internet lack any support from sound scientific evidence.

TL;DR: In this paper , the authors evaluated whether adolescent exposure to the drug's psychotropic component, Δ9-tetrahydrocannabinol (THC), might persistently alter microglia function.

TL;DR: In this paper, the molecular events leading to chronic pain emergence and its emergence in humans are investigated. But, they remain woefully under-diagnosed and need to discover disease-modifying therapies.