Alexandros Papachristofilou

TL;DR: The aim of the conference was to develop detailed recommendations on topics relating to testicular cancer that are not covered in detail in the current ESMO Clinical Practice Guidelines (CPGs) and where the available level of evidence is insufficient.

TL;DR: After an initial learning curve with regards to total cumulative doses, consistently high biologically effective doses have been employed translating into high local tumor control at 1 and 2 years and overall survival is mainly influenced by histology and metastatic tumor burden.

TL;DR: In comparison to baseline, immunomonitoring revealed increased BI1361849 antigen-specific immune responses in the majority of patients (84%), whereby antigen- specific antibody levels were increased in 80% and functional T cells in 40% of patients, and involvement of multiple antigen specificities was evident in 52% of Patients.

TL;DR: Dose-intensified SRT was associated with low rates of acute grade 2 and 3 GU and GI toxicity and the impact of dose intensification on QoL was minor, except for a significantly greater worsening in urinary symptoms.

TL;DR: This trial will assess the safety and tolerability of CV9202 vaccination combined with local radiation designed to enhance immune responses and will include patients with stage IV NSCLC and a response or stable disease after first-line chemotherapy or therapy with an EGFR tyrosine kinase inhibitor.