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Alice R Carter
Researcher at University of Bristol
Publications - 37
Citations - 480
Alice R Carter is an academic researcher from University of Bristol. The author has contributed to research in topics: Medicine & Body mass index. The author has an hindex of 6, co-authored 25 publications receiving 182 citations.
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Journal ArticleDOI
Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study
Alice R Carter,Dipender Gill,Neil M Davies,Amy E Taylor,Amy E Taylor,Taavi Tillmann,Julien Vaucher,Robyn E Wootton,Robyn E Wootton,Marcus R. Munafò,Gibran Hemani,Rainer Malik,Sudha Seshadri,Daniel Woo,Stephen Burgess,Stephen Burgess,George Davey Smith,George Davey Smith,Michael V. Holmes,Michael V. Holmes,Michael V. Holmes,Ioanna Tzoulaki,Ioanna Tzoulaki,Laura D Howe,Abbas Dehghan +24 more
TL;DR: BMI, systolic blood pressure, and smoking behaviour mediate a substantial proportion of the protective effect of education on the risk of cardiovascular outcomes and intervening on these would lead to reductions in cases of cardiovascular disease attributable to lower levels of education.
Journal ArticleDOI
Mendelian randomisation for mediation analysis: current methods and challenges for implementation
Alice R Carter,Eleanor Sanderson,Gemma Hammerton,Rebecca C Richmond,George Davey Smith,George Davey Smith,Jon Heron,Amy E Taylor,Amy E Taylor,Neil M Davies,Neil M Davies,Laura D Howe +11 more
TL;DR: In this article, Mendelian randomisation (MR) is used to improve causal inference for mediation analysis, where these assumptions are more plausible, and two approaches that can be used for estimating mediation analysis with MR: multivariable MR (MVMR) and two-step MR.
Journal ArticleDOI
Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis.
Dipender Gill,Verena Zuber,Verena Zuber,Jesse Dawson,Jonathan Pearson-Stuttard,Alice R Carter,Eleanor Sanderson,Ville Karhunen,Michael G. Levin,Michael G. Levin,Robyn E Wootton,Robyn E Wootton,Derek Klarin,Philip S. Tsao,Philip S. Tsao,Konstantinos K. Tsilidis,Konstantinos K. Tsilidis,Scott M. Damrauer,Scott M. Damrauer,Stephen Burgess,Paul Elliott +20 more
TL;DR: In this article, Mendelian randomization mediation analysis was performed to investigate the degree to which systolic blood pressure (SBP), diabetes, lipid traits, and smoking mediated an effect of BMI and waist-to-hip ratio (WHR) on the risk of coronary artery disease, peripheral artery disease (PAD), and stroke.
Journal ArticleDOI
Bias from questionnaire invitation and response in COVID-19 research: an example using ALSPAC
Alba Fernández-Sanlés,Daniel J. Smith,Gemma L. Clayton,Kate Northstone,Alice R Carter,Louise A C Millard,Maria Carolina Borges,Nicholas J. Timpson,Kate Tilling,Gareth J Griffith,Debbie A Lawlor +10 more
TL;DR: Ass associations of pre-pandemic sociodemographic, behavioural, anthropometric and health-related factors with questionnaire invitation and response in COVID-19 questionnaire data collection in a multigenerational birth cohort are assessed.
Posted ContentDOI
Risk factors mediating the effect of body-mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis
Dipender Gill,Verena Zuber,Jesse Dawson,Jonathan Pearson-Stuttard,Alice R Carter,Eleanor Sanderson,Ville Karhunen,Michael G. Levin,Robyn E Wootton,Derek Klarin,Philip S. Tsao,Konstantinos K. Tsilidis,Scott M. Damrauer,Stephen Burgess,Paul Elliott +14 more
TL;DR: Reduction of obesity prevalence alongside control and management of its mediators is likely to be most effective for minimizing the burden of obesity.