A
Alison M. Wren
Researcher at Imperial College London
Publications - 22
Citations - 12479
Alison M. Wren is an academic researcher from Imperial College London. The author has contributed to research in topics: Ghrelin & Appetite. The author has an hindex of 19, co-authored 22 publications receiving 12069 citations.
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Journal ArticleDOI
Ghrelin enhances appetite and increases food intake in humans.
Alison M. Wren,L. J. Seal,Mark Cohen,Audrey E. Brynes,Gary Frost,Kevin Murphy,Waljit S. Dhillo,M. A. Ghatei,S.R. Bloom +8 more
TL;DR: Ghrelin is the first circulating hormone demonstrated to stimulate food intake in man and is a potentially important new regulator of the complex systems controlling food intake and body weight.
Journal ArticleDOI
Gut hormone PYY 3-36 physiologically inhibits food intake
Rachel L. Batterham,Michael A. Cowley,Caroline J. Small,Herbert Herzog,Mark Cohen,C. L. Dakin,Alison M. Wren,Audrey E. Brynes,Malcolm J. Low,Mohammad A. Ghatei,Roger D. Cone,Stephen R. Bloom +11 more
TL;DR: In this paper, the authors showed that post-prandial elevation of PYY3-36 may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway.
Journal Article
BRIEF COMMUNICATION ARISING: Gut hormone PYY3-36 physiologically inhibits food intake
Rachel L. Batterham,Michael A. Cowley,Caroline J. Small,Herbert Herzog,Mark A Cohen,C. L. Dakin,Alison M. Wren,Audrey E. Brynes,Malcolm J. Low +8 more
TL;DR: The authors showed that post-prandial elevation of PYY3-36 may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway.
Journal ArticleDOI
The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion
Alison M. Wren,Caroline J. Small,Helen L. Ward,K. G. Murphy,C. L. Dakin,Shahrad Taheri,A Kennedy,G. H. Roberts,David G.A. Morgan,M. A. Ghatei,Stephen R. Bloom +10 more
TL;DR: It is found that both intracerebroventricular and intraperitoneal administration of ghrelin in freely feeding rats stimulated food intake and plasma growth hormone (GH) concentration increased following both i.c.v. and i.p. administration.
Journal ArticleDOI
Ghrelin Causes Hyperphagia and Obesity in Rats
Alison M. Wren,Caroline J. Small,Caroline R. Abbott,Waljit S. Dhillo,L. J. Seal,Mark Cohen,Rachel L. Batterham,Shahrad Taheri,Sarah Stanley,Mohammad A. Ghatei,Stephen R. Bloom +10 more
TL;DR: Evidence is provided that ghrelin is important in long-term control of food intake and body weight and that circulating gh Relin at fasting concentrations may stimulate food intake.