A
Almut Schulze
Researcher at German Cancer Research Center
Publications - 114
Citations - 15675
Almut Schulze is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 47, co-authored 98 publications receiving 12018 citations. Previous affiliations of Almut Schulze include Lincoln's Inn & London Research Institute.
Papers
More filters
Journal ArticleDOI
Cellular fatty acid metabolism and cancer
TL;DR: Evidence that limiting fatty acid availability can control cancer cell proliferation is summarized, and a view of cancer cell metabolism from a lipid perspective is provided.
Journal ArticleDOI
FSP1 is a glutathione-independent ferroptosis suppressor
Sebastian Doll,Florencio Porto Freitas,Ron Shah,Maceler Aldrovandi,Milene Costa da Silva,Irina Ingold,Andrea Goya Grocin,Thamara Nishida Xavier da Silva,Elena Panzilius,Christina Scheel,André Mourão,Katalin Buday,Mami Sato,Jonas Wanninger,Thibaut Vignane,Vaishnavi Mohana,Markus Rehberg,Andrew Flatley,Aloys Schepers,Andreas Kurz,Daniel A. White,Markus Sauer,Michael Sattler,Edward W. Tate,Werner Schmitz,Almut Schulze,Valerie B. O'Donnell,Bettina Proneth,Grzegorz M. Popowicz,Derek A. Pratt,José Pedro Friedmann Angeli,Marcus Conrad +31 more
TL;DR: The FSP1–CoQ10–NAD(P)H pathway exists as a stand-alone parallel system, which co-operates with GPX4 and glutathione to suppress phospholipid peroxidation and ferroptosis in cells.
Journal ArticleDOI
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
Thomas Porstmann,Claudio R. Santos,B. Griffiths,Megan Cully,Mary Wu,Sally J. Leevers,John R. Griffiths,Yuen-Li Chung,Almut Schulze +8 more
TL;DR: The results suggest that the PI3K/Akt/TOR pathway regulates protein and lipid biosynthesis in an orchestrated manner and that both processes are required for cell growth.
Journal ArticleDOI
Lipid metabolism in cancer
Claudio R. Santos,Almut Schulze +1 more
TL;DR: This review will examine some of the alterations in lipid metabolism that have been reported in cancer, at both cellular and organismal levels, and discuss how they contribute to different aspects of tumourigenesis.
Journal ArticleDOI
The multifaceted roles of fatty acid synthesis in cancer
Florian Röhrig,Almut Schulze +1 more
TL;DR: This Review explores how different aspects of FA synthesis promote tumorigenesis and tumour progression and strategies to target this pathway have not yet translated into clinical practice.