E
Erin Currie
Researcher at University of California, San Francisco
Publications - 5
Citations - 2851
Erin Currie is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lipid droplet & Lipid metabolism. The author has an hindex of 5, co-authored 5 publications receiving 2272 citations.
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Journal ArticleDOI
Cellular fatty acid metabolism and cancer
TL;DR: Evidence that limiting fatty acid availability can control cancer cell proliferation is summarized, and a view of cancer cell metabolism from a lipid perspective is provided.
Journal ArticleDOI
An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen
Benoît Kornmann,Erin Currie,Sean R. Collins,Maya Schuldiner,Jodi Nunnari,Jonathan S. Weissman,Peter Walter +6 more
TL;DR: In this article, the authors identified the Mmm1/Mdm10/mdm12/mdr34 complex as a molecular tether between the endoplasmic reticulum (ER) and mitochondria.
Journal ArticleDOI
In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy
Dan Fu,Yong Yu,Andrew Folick,Erin Currie,Robert V. Farese,Tsung-Huang Tsai,Xiaoliang Sunney Xie,Meng C. Wang +7 more
TL;DR: It is found that unsaturated fatty acid has preferential uptake into lipid storage while saturated fatty acid exhibits toxicity in hepatic cells, unlike previously hypothesized.
Journal ArticleDOI
High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation.
Erin Currie,Xiuling Guo,Romain Christiano,Chandramohan Chitraju,Nora Kory,Kenneth D. Harrison,Joel T. Haas,Tobias C. Walther,Robert V. Farese +8 more
TL;DR: This work uses protein correlation profiling to identify 35 proteins that specifically enrich with LD fractions of Saccharomyces cerevisiae and reveals that the vast majority are involved in lipid metabolism.
Supporting Online Material for An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen
TL;DR: A large-scale genetic interaction map suggests that these ER-mitochondria connections are important for interorganellar phospholipid exchange, and shows that discrete sites of close apposition between ER and mitochondria facilitate interorganelle calcium and phospholIPid exchange.