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Alok C. Bharti
Researcher at University of Delhi
Publications - 102
Citations - 8483
Alok C. Bharti is an academic researcher from University of Delhi. The author has contributed to research in topics: Cancer & Cervical cancer. The author has an hindex of 38, co-authored 95 publications receiving 7744 citations. Previous affiliations of Alok C. Bharti include Indian Council of Medical Research & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions
Ajay K. Chaudhary,Ajay K. Chaudhary,Mamta Singh,Alok C. Bharti,Mangal Singh,Shirish Shukla,Atul K. Singh,Ravi Mehrotra +7 more
TL;DR: In patients with OSMF as well as HNSCC, the ROC analysis between the MMP-3 genotype and age, 6A/6A allele was found to be significant in patients both over and under 45 years of age; while the 5A/5A carrier alleles showed an association only in patients less than 45 years- age.
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BASANT, a Polyherbal Safe Microbicide Eliminates HPV-16 in Women with Early Cervical Intraepithelial Lesions
Gursaran P. Talwar,Rajyashree Sharma,Sonal Singh,Bhudev C. Das,Alok C. Bharti,Kirti Sharma,Priyanka Singh,Nishu Atrey,Jagdish C. Gupta +8 more
TL;DR: The elimination of HPV-16 from the infected cells of all (11/11) women positive for HPV- 16 by 30 intra-vaginal intakes of BASANT is reported.
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Overexpression of STAT3 in HPV-mediated cervical cancer in a north Indian population.
Ranbir Chander Sobti,Neha Singh,Showket Hussain,Vanita Suri,Alok C. Bharti,Bhudev C. Das,Bhudev C. Das +6 more
TL;DR: Results indicate a potentially interactive effect between HPV 16/18 and transcriptional activation of STAT3 gene in cervical carcinogenesis and its possible interaction with HPV infection status, first such study to be reported from India.
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Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity.
Abhishek Tyagi,Abhishek Tyagi,Abhishek Tyagi,Kanchan Vishnoi,Harsimrut Kaur,Yogesh Srivastava,Bal Gangadhar Roy,Bhudev C. Das,Bhudev C. Das,Alok C. Bharti,Alok C. Bharti +10 more
TL;DR: A critical role of AP-1 protein in the manifestation of radioresistance but targeting with curcumin helps in radiosensitizing CaCxSLCs through upregulation of Fra-1 is suggested.
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Functional polymorphism of the MMP-1 promoter (-1607 1G/2G) in potentially malignant and malignant head and neck lesions in an Indian population.
TL;DR: It is concluded that SNPs in the MMP1 promoter region may be associated with susceptibility to oral submucous fibrosis as well as HNSCC in an Indian population and addiction habits such as areca nut chewing and alcohol abuse may enhance the expression of the 2G allele of M MP1 genes in OSMF and H NSCC cases.