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Alok C. Bharti
Researcher at University of Delhi
Publications - 102
Citations - 8483
Alok C. Bharti is an academic researcher from University of Delhi. The author has contributed to research in topics: Cancer & Cervical cancer. The author has an hindex of 38, co-authored 95 publications receiving 7744 citations. Previous affiliations of Alok C. Bharti include Indian Council of Medical Research & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck
TL;DR: The objective of this review is to discuss the molecular functions and polymorphic association of MMPs and TIMPs and the possible therapeutic aspects of these proteinases in potentially malignant and malignant head and neck lesions and the development of their potential diagnostic and therapeutic possibilities.
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Elimination of high-risk human papillomavirus type HPV16 infection by 'Praneem' polyherbal tablet in women with early cervical intraepithelial lesions.
Shirish Shukla,Alok C. Bharti,Showket Hussain,Sutapa Mahata,Suresh Hedau,Uma Kailash,Veena Kashyap,Suresh Bhambhani,M.S. Roy,Swaraj Batra,Gursaran P. Talwar,Bhudev C. Das,Bhudev C. Das +12 more
TL;DR: Results showed for the first time that a 30-day intra-vaginal application of the Praneem can result in elimination of HPV infection from the uterine cervix.
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Breast cancer and human papillomavirus infection: No evidence of HPV etiology of breast cancer in Indian women
Suresh Hedau,Umesh Kumar,Showket Hussain,Shirish Shukla,Shailja Pande,Neeraj Jain,Abhishek Tyagi,Trivikram M Deshpande,Dilafroze Bhat,Mohammad Muzaffar Mir,Sekhar Chakraborty,Y Mohan Singh,Rakesh Kumar,Kumaravel Somasundaram,Alok C. Bharti,Bhudev C. Das,Bhudev C. Das +16 more
TL;DR: Lack of detection of HPV DNA either in the tumor or in the blood DNA of breast cancer patients by both conventional and real time PCR does not support a role of genital HPV in the pathogenesis of breast cancers in Indian women.
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Alterations in microRNAs miR-21 and let-7a correlate with aberrant STAT3 signaling and downstream effects during cervical carcinogenesis
Gauri Shishodia,Gauri Shishodia,Shirish Shukla,Yogesh Srivastava,Shashank Masaldan,Sumita Mehta,Suresh Bhambhani,Shashi Sharma,Ravi Mehrotra,Bhudev C. Das,Alok C. Bharti +10 more
TL;DR: Overall, this study suggests that the microRNAs, miR-21 and let-7a function as clinically relevant integral components of STAT3 signaling and are responsible for maintaining activated state ofSTAT3 in HPV-infected cells during cervical carcinogenesis.
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Cervical Cancer Stem Cells Selectively Overexpress HPV Oncoprotein E6 that Controls Stemness and Self-Renewal through Upregulation of HES1
Abhishek Tyagi,Kanchan Vishnoi,Sutapa Mahata,Gaurav Verma,Yogesh Srivastava,Shashank Masaldan,Bal Gangadhar Roy,Alok C. Bharti,Alok C. Bharti,Bhudev C. Das,Bhudev C. Das +10 more
TL;DR: The findings suggest the possible mechanism by which HPVE6 potentially regulate and maintain stem-like cancer cells through Hes1, and suggest the role of viral oncoproteins in stem cell signaling and maintenance in cervical cancer.