A
Alok C. Bharti
Researcher at University of Delhi
Publications - 102
Citations - 8483
Alok C. Bharti is an academic researcher from University of Delhi. The author has contributed to research in topics: Cancer & Cervical cancer. The author has an hindex of 38, co-authored 95 publications receiving 7744 citations. Previous affiliations of Alok C. Bharti include Indian Council of Medical Research & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Piceatannol Inhibits TNF-Induced NF-κB Activation and NF-κB-Mediated Gene Expression Through Suppression of IκBα Kinase and p65 Phosphorylation
Kazuhiro Ashikawa,Sekhar Majumdar,Sanjeev Banerjee,Alok C. Bharti,Shishir Shishodia,Bharat B. Aggarwal +5 more
TL;DR: It is demonstrated that hydroxyl groups of stilbenes are critical and that piceatannol, a tetrahydroxystilbene, suppresses NF-κB activation induced by various inflammatory agents through inhibition of IκBα kinase and p65 phosphorylation.
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Curcumin (Diferuloylmethane) Inhibits Receptor Activator of NF-κB Ligand-Induced NF-κB Activation in Osteoclast Precursors and Suppresses Osteoclastogenesis
TL;DR: Results indicate that RANKL induces osteoclastogenesis through the activation of NF-κB, and treatment with curcumin inhibits both the NF-σκB activation and osteOClastogenesis induced by RankL.
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Chronic diseases, inflammation, and spices: how are they linked?
Ajaikumar B. Kunnumakkara,Bethsebie Lalduhsaki Sailo,Kishore Banik,Choudhary Harsha,Sahdeo Prasad,Subash C. Gupta,Alok C. Bharti,Bharat B. Aggarwal +7 more
TL;DR: The potential of various dietary agents such as spices and its components in the suppression of inflammatory pathways and their roles in the prevention and therapy of cancer and other chronic diseases are discussed.
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Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
TL;DR: It is proposed that berberine is a potentially promising compound for the treatment of cervical cancer infected with HPV through inhibition of AP-1 and blocking viral oncoproteins E6 and E7 expression.
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The role of TNF and its family members in inflammation and cancer: lessons from gene deletion.
TL;DR: The signal transduction pathways used by the members of the TNF family and the effects of deletion of genes that mediate the pathways are elucidated to serve as a target for the development of therapeutics.