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Alok C. Bharti
Researcher at University of Delhi
Publications - 102
Citations - 8483
Alok C. Bharti is an academic researcher from University of Delhi. The author has contributed to research in topics: Cancer & Cervical cancer. The author has an hindex of 38, co-authored 95 publications receiving 7744 citations. Previous affiliations of Alok C. Bharti include Indian Council of Medical Research & University of Texas MD Anderson Cancer Center.
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Multifunctional ATRP based pH responsive polymeric nanoparticles for improved doxorubicin chemotherapy in breast cancer by proton sponge effect/endo-lysosomal escape
Shantanu V. Lale,Shantanu V. Lale,Arun Kumar,Arun Kumar,Farhat Naz,Alok C. Bharti,Veena Koul,Veena Koul +7 more
TL;DR: In vitro and in vivo studies in breast cancer cell lines and Ehrlich ascites tumor bearing Swiss albino mice showed enhanced cellular uptake and improved therapeutic efficacy of the nanosystem with nanoparticles achieving ∼92% tumor regression when compared to ∼36% tumors regression observed with free doxorubicin.
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Transactivation and expression patterns of Jun and Fos/AP-1 super-family proteins in human oral cancer.
TL;DR: In this paper, the activation and expression pattern of AP-1 family of proteins and mRNA in different stages of oral carcinogenesis was studied, and the role of AP1 during development of human oral cancers is still poorly understood.
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Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein
TL;DR: The results demonstrate existence of a functional loop involving Let-7a, STAT3 and miR-21 which were found potentially regulated by viral oncoprotein E6.
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Anticancer Activity of Phyllanthus emblica Linn. (Indian Gooseberry): Inhibition of Transcription Factor AP-1 and HPV Gene Expression in Cervical Cancer Cells
Sutapa Mahata,Arvind Pandey,Shirish Shukla,Abhishek Tyagi,Syed Akhtar Husain,Bhudev C. Das,Alok C. Bharti +6 more
TL;DR: The results suggest that P. emblica exhibits its anticancer activities through inhibition of AP-1 and targets transcription of viral oncogenes responsible for development and progression of cervical cancer thus indicating its possible utility for treatment of HPV-induced cervical cancers.
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Preparation and in vitro evaluation of folate-receptor-targeted SPION-polymer micelle hybrids for MRI contrast enhancement in cancer imaging.
TL;DR: The biological evaluation of the SPION micelles included cellular viability assay (MTT) and uptake in HeLa cells and the potential use of these nanoplatforms for imaging and targeting was demonstrated.