A
Amardeep Kaur
Researcher at Institute for Systems Biology
Publications - 31
Citations - 2634
Amardeep Kaur is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 18, co-authored 29 publications receiving 2431 citations. Previous affiliations of Amardeep Kaur include University of Washington.
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Journal ArticleDOI
The evolution of vertebrate Toll-like receptors
Jared C. Roach,Gustavo Glusman,Lee Rowen,Amardeep Kaur,Maureen K. Purcell,Kelly D. Smith,Leroy Hood,Alan Aderem +7 more
TL;DR: The complete sequences of Takifugu Toll-like receptor (TLR) loci and gene predictions from many draft genomes enable comprehensive molecular phylogenetic analysis and shows that coincidental evolution plays a minor role in TLR evolution.
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A Predictive Model for Transcriptional Control of Physiology in a Free Living Cell
Richard Bonneau,Richard Bonneau,Marc T. Facciotti,David J Reiss,Amy K. Schmid,Min Pan,Amardeep Kaur,Vesteinn Thorsson,Paul Shannon,Michael H. Johnson,J. Christopher Bare,William J.R. Longabaugh,Madhavi Vuthoori,Kenia Whitehead,Aviv Madar,Lena Suzuki,Tetsuya Mori,Dong Eun Chang,Jocelyne DiRuggiero,Carl Hirschie Johnson,Leroy Hood,Nitin S. Baliga,Nitin S. Baliga +22 more
TL;DR: This study supports the claim that the high degree of connectivity within biological and EF networks will enable the construction of similar models for any organism from relatively modest numbers of experiments.
Journal ArticleDOI
Analysis of the Human Neurexin Genes: Alternative Splicing and the Generation of Protein Diversity
Lee Rowen,Janet M. Young,Brian Birditt,Amardeep Kaur,Anup Madan,Dana L. Philipps,Shizhen Qin,Patrick Minx,Richard K. Wilson,Leroy Hood,Brenton R. Graveley +10 more
TL;DR: The complete nucleotide sequence of all three human neurexin genes is determined and several conserved intronic sequence elements that may participate in the regulation of alternative splicing are identified.
Journal ArticleDOI
General transcription factor specified global gene regulation in archaea
Marc T. Facciotti,David J Reiss,Min Pan,Amardeep Kaur,Madhavi Vuthoori,Richard Bonneau,Paul Shannon,Alok Srivastava,Samuel Donohoe,Leroy Hood,Nitin S. Baliga +10 more
TL;DR: Experimental evidence is provided for how archaea likely accomplish similar large-scale transcriptional segregation and modulation of physiological functions and provides an example for how to use various experimental techniques to rapidly learn significant portions of a global gene regulatory network of organisms for which little has been previously known.
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A systems view of haloarchaeal strategies to withstand stress from transition metals
TL;DR: An integrated perspective of responses to six transition metals with emphasis on experimentally verified regulatory mechanisms is provided to provide insights into putative in vivo metal selectivity of metalloregulatory proteins and demonstrate that a systems approach can help rapidly unravel novel metabolic potential and regulatory programs of poorly studied organisms.