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Amit Rai
Researcher at Babasaheb Bhimrao Ambedkar University
Publications - 35
Citations - 395
Amit Rai is an academic researcher from Babasaheb Bhimrao Ambedkar University. The author has contributed to research in topics: ATP synthase & Docking (molecular). The author has an hindex of 10, co-authored 34 publications receiving 274 citations. Previous affiliations of Amit Rai include University of Padua.
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Isolated mangiferin and naringenin exert antidiabetic effect via PPARγ/GLUT4 dual agonistic action with strong metabolic regulation.
Ashok K. Singh,Vinit Raj,Amit K Keshari,Amit Rai,Pranesh Kumar,Atul Rawat,Biswanath Maity,Dinesh Kumar,Anand Prakash,Arnab De,Amalesh Samanta,Bolay Bhattacharya,Sudipta Saha +12 more
TL;DR: SA1 and SA2 might be potential antidiabetic lead compounds for future drug development after it was suggested that both compounds reduced blood glucose level, restored body weight, and normalized lipid concentrations in the serum and oxidative stress biomarkers in the liver and pancreas.
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Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations.
Pranesh Kumar,Ashok K. Singh,Vinit Raj,Amit Rai,Amit K Keshari,Dinesh Kumar,Biswanath Maity,Anand Prakash,Sabyasachi Maiti,Sudipta Saha +9 more
TL;DR: The prepared BNP showed a better therapeutic response against HCC and could be attributed as future candidate molecule for HCC treatment.
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Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling
Vinit Raj,Archana S. Bhadauria,Ashok K. Singh,Umesh Kumar,Amit Rai,Amit K Keshari,Pranesh Kumar,Dinesh Kumar,Biswanath Maity,Sneha Nath,Anand Prakash,Kausar M. Ansari,Jawahar L. Jat,Sudipta Saha +13 more
TL;DR: The tumor protecting ability of VR24 and VR27 was found comparable or to some degree better than the marketed chemotherapeutics, 5-flurouracil.
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Ectopic F0F 1 ATP synthase contains both nuclear and mitochondrially-encoded subunits.
TL;DR: Using different methods to prepare rat liver plasma membranes, it is demonstrated the presence of ecto-F0F1 complexes which have a similar molecular weight to the monomeric form of the mitochondrial complexes, containing both nuclear and mitochondrially-encoded subunits.
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p -TSA-promoted syntheses of 5H-benzo[h]thiazolo[2,3-b]quinazoline and indeno[1,2-d]thiazolo[3,2-a]pyrimidine analogs: molecular modeling and in vitro antitumor activity against hepatocellular carcinoma
Amit K Keshari,Ashok K. Singh,Vinit Raj,Amit Rai,Prakruti Trivedi,Balaram Ghosh,Umesh Kumar,Atul Rawat,Dinesh Kumar,Sudipta Saha +9 more
TL;DR: The results of the comprehensive structure–activity relationship study confirmed the assumption that two or more electronegative groups on the phenyl ring attached to the thiazolo[2,3-b]quinazoline system showed the optimum effect, and 4A and 6A are potential drug candidates for the management of HCC.