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Amy Cunningham-Bussel
Researcher at Brigham and Women's Hospital
Publications - 16
Citations - 1741
Amy Cunningham-Bussel is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Amygdala & Cytotoxic T cell. The author has an hindex of 10, co-authored 15 publications receiving 1433 citations. Previous affiliations of Amy Cunningham-Bussel include Cornell University & Columbia University.
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Journal ArticleDOI
Beyond oxidative stress: an immunologist’s guide to reactive oxygen species
TL;DR: ROS chemistry and their pleiotropy make them difficult to localize, to quantify and to manipulate — challenges the authors must overcome to translate ROS biology into medical advances.
Journal ArticleDOI
NOD2 regulates hematopoietic cell function during graft-versus-host disease
Olaf Penack,Olaf Penack,Odette M. Smith,Amy Cunningham-Bussel,Xin Liu,Uttam K. Rao,Nury L. Yim,Il-Kang Na,Il-Kang Na,Amanda M. Holland,Amanda M. Holland,Arnab Ghosh,Sydney X. Lu,Robert R. Jenq,Chen Liu,George F. Murphy,Katharina Brandl,Marcel R.M. van den Brink +17 more
TL;DR: It is found that proliferation and activation of donor T cells was enhanced in NOD-deficient allo-BMT recipients, suggesting that NOD2 plays a role in the regulation of host antigen-presenting cells (APCs).
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Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials
Ben Gold,Maneesh Pingle,Steven J. Brickner,Nilesh Shah,Julia Roberts,Mark Rundell,W. Clay Bracken,Thulasi Warrier,Selin Somersan,Aditya Venugopal,Crystal M. Darby,Xiuju Jiang,J. David Warren,Joseph Fernandez,Ouathek Ouerfelli,Eric L. Nuermberger,Amy Cunningham-Bussel,Poonam Rath,Tamutenda Chidawanyika,Haiteng Deng,Ronald Realubit,J. Fraser Glickman,Carl Nathan +22 more
TL;DR: This article devised a high-throughput screen for compounds that kill Mycobacterium tuberculosis (Mtb) when its replication has been halted by reactive nitrogen intermediates (RNIs), acid, hypoxia, and a fatty acid carbon source.
Journal ArticleDOI
Human fear-related motor neurocircuitry
Tracy Butler,Hong Pan,Oliver Tuescher,Almut Engelien,Marc Goldstein,Jane Epstein,Daniel S. Weisholtz,James C. Root,Xenia Protopopescu,Amy Cunningham-Bussel,Luke J. Chang,X.-H. Xie,Qiang Chen,Elizabeth A. Phelps,Joseph E. LeDoux,Emily Stern,David Silbersweig +16 more
TL;DR: A striking pattern of decreased activity in primary motor cortex with increased activity in dorsal basal ganglia during anticipation of aversive electrodermal stimulation is observed and is interpreted in response to cognitively-induced fear in relation to evolutionarily-conserved responses to threat.
Journal ArticleDOI
Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression
TL;DR: It is found that Mtb infecting human macrophages in vitro produces copious nitrite at physiologic oxygen tensions, which may slow Mtb’s growth and prepare it to resist host stresses while the pathogen waits for immunopathology to promote its transmission.