A
Angelo Ferraro
Researcher at University of Naples Federico II
Publications - 34
Citations - 3297
Angelo Ferraro is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Thyroid carcinoma & Thyroid. The author has an hindex of 27, co-authored 32 publications receiving 3090 citations.
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Journal ArticleDOI
MicroRNA deregulation in human thyroid papillary carcinomas
Pierlorenzo Pallante,Rosa Visone,Rosa Visone,Manuela Ferracin,Angelo Ferraro,Mt Berlingieri,Giancarlo Troncone,Gennaro Chiappetta,Cg Liu,Massimo Santoro,Massimo Negrini,Carlo M. Croce,Alfredo Fusco +12 more
TL;DR: Analysis of genome-wide miRNA expression profile in human thyroid papillary carcinomas and functional studies suggest a critical role of miR-221 overexpression in thyroid carcinogenesis suggest miRNA deregulation as an important event in thyroid cell transformation.
Journal ArticleDOI
MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycle.
Rosa Visone,Lucia Russo,Pierlorenzo Pallante,Ivana De Martino,Angelo Ferraro,Vincenza Leone,Eleonora Borbone,Fabio Petrocca,Hansjuerg Alder,Carlo M. Croce,Alfredo Fusco +10 more
TL;DR: The data reported here demonstrate that MiR-221 and miR-222 are endogenous regulators of p27(Kip1) protein expression, and thereby, the cell cycle.
Journal ArticleDOI
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.
Rosa Visone,Pierlorenzo Pallante,Andrea Vecchione,Roberto Cirombella,Manuela Ferracin,Angelo Ferraro,Stefano Volinia,Sabrina Coluzzi,Vincenza Leone,Eleonora Borbone,Chang Gong Liu,Fabio Petrocca,Giancarlo Troncone,George A. Calin,Aldo Scarpa,Chiara Colato,Giovanni Tallini,Massimo Santoro,Carlo M. Croce,Alfredo Fusco +19 more
TL;DR: Analysis of the microRNA profile of ATC in comparison to the normal thyroid using a microarray suggests a miR signature associated with ATC and suggests the miR deregulation as an important event in thyroid cell transformation.
Journal ArticleDOI
Increased BDNF promoter methylation in the Wernicke area of suicide subjects.
Simona Keller,Marco Sarchiapone,Federica Zarrilli,Alja Videtic,Angelo Ferraro,Vladimir Carli,Silvana Sacchetti,Francesca Lembo,Antonella Angiolillo,Nikolina Jovanović,Francesco Pisanti,Rossella Tomaiuolo,Antonella Monticelli,Joze Balazic,Alec Roy,Andrej Marusic,Sergio Cocozza,Alfredo Fusco,Carmelo B. Bruni,Giuseppe Castaldo,Lorenzo Chiariotti +20 more
TL;DR: BDNF promoter/exon IV is frequently hypermethylated in the Wernicke area of the postmortem brain of suicide subjects irrespective of genome-wide methylation levels, indicating that a gene-specific increase in DNA methylation could cause or contribute to the downregulation of BDNF expression in suicide subjects.
Journal ArticleDOI
Upregulation of miR-21 by Ras in vivo and its role in tumor growth
Daniela Frezzetti,M De Menna,Pietro Zoppoli,Carmen Guerra,Angelo Ferraro,Anna Maria Bello,P. De Luca,Cecilia Calabrese,Alfredo Fusco,Michele Ceccarelli,Massimo Zollo,Mariano Barbacid,R Di Lauro,G De Vita +13 more
TL;DR: It is shown that miR-21 is upregulated both in vitro and in vivo by oncogenic Ras, thus linking this miRNA to one of the most frequently activated oncogenes in human cancers.