A
Anja Feldmann
Researcher at Max Planck Society
Publications - 368
Citations - 18932
Anja Feldmann is an academic researcher from Max Planck Society. The author has contributed to research in topics: The Internet & Antigen. The author has an hindex of 67, co-authored 340 publications receiving 17422 citations. Previous affiliations of Anja Feldmann include Saarland University & AT&T.
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Journal ArticleDOI
From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.
Susann Albert,Claudia Arndt,Stefanie Koristka,Nicole Berndt,Ralf Bergmann,Anja Feldmann,Marc Schmitz,Marc Schmitz,Jens Pietzsch,Jens Pietzsch,Jörg Steinbach,Jörg Steinbach,Michael Bachmann +12 more
TL;DR: A novel bivalent α- EGFR-EGFR TM is described, which could redirect UniCAR T cells to tumor cells expressing low levels of EGFR and improve the enrichment at the tumor site and its use for PET imaging.
Journal ArticleDOI
Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy
Roberta Aliperta,Petra B. Welzel,Ralf Bergmann,Uwe Freudenberg,Nicole Berndt,Anja Feldmann,Claudia Arndt,Stefanie Koristka,Marcello Stanzione,Marc Cartellieri,Armin Ehninger,Gerhard Ehninger,Carsten Werner,Carsten Werner,Jens Pietzsch,Jens Pietzsch,Jörg Steinbach,Jörg Steinbach,Martin Bornhäuser,Michael Bachmann +19 more
TL;DR: An innovative immunotherapeutic organoid by housing human mesenchymal stromal cells, gene-modified for the secretion of an anti-CD33-anti-CD3 bispecific antibody in a small biocompatible star-shaped poly(ethylene glycol)-heparin cryogel scaffold as a transplantable and low invasive therapeutic machinery for the treatment of acute myeloid leukemia (AML).
Web Search Clickstreams
Nils Kammenhuber,Julia Luxenburger,Anja Feldmann,Gerhard Weikum,Jussara M. Almeida,Virgilio Almeida,Paul Barford +6 more
Proceedings ArticleDOI
Energy trade-offs among content delivery architectures
Anja Feldmann,Andreas Gladisch,Mario Kind,Christoph Lange,Georgios Smaragdakis,Fritz-Joachim Westphal +5 more
TL;DR: The results show that a CDN within an ISP is able to minimize the overall power consumption and a P2P architecture may reduce the power consumption of the service provider it increases the overall energy consumption.
Journal ArticleDOI
Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia.
Simon Loff,Josephine Dietrich,Jan-Erik Meyer,Julia Riewaldt,Johannes Spehr,Malte von Bonin,Cordula Gründer,Mridula Swayampakula,Kristin Franke,Anja Feldmann,Michael Bachmann,Gerhard Ehninger,Armin Ehninger,Marc Cartellieri +13 more
TL;DR: UniCAR maintains full anti-leukemic efficacy, while ensuring rapid controllability to improve safety and versatility of CD123-directed immunotherapy, as well as demonstrating a pre-clinical proof of concept for the safety-switch mechanism using a hematotoxicity mouse model.