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Anja Feldmann
Researcher at Max Planck Society
Publications - 368
Citations - 18932
Anja Feldmann is an academic researcher from Max Planck Society. The author has contributed to research in topics: The Internet & Antigen. The author has an hindex of 67, co-authored 340 publications receiving 17422 citations. Previous affiliations of Anja Feldmann include Saarland University & AT&T.
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Tregs activated by bispecific antibodies: Killers or suppressors?
Stefanie Koristka,Marc Cartellieri,Claudia Arndt,Anja Feldmann,Barbara Seliger,Gerhard Ehninger,Michael Bachmann +6 more
TL;DR: Bispecific antibodies for target-specific redirection of T cells in order to eliminate malignant cells and CD3-engaging constructs might also activate T regulatory cells present in the tumor microenvironment.
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Redirection of Immune Effector Cells by Bispecific Antibody Systems for the Treatment of Acute Myeloid Leukemia
Claudia Arndt,Anja Feldmann,Stefanie Koristka,Irene Michalk,Marc Cartellieri,Slava Stamova,Malte von Bonin,Martin Bornhäuser,Gerhard Ehninger,Michael Bachmann +9 more
TL;DR: The obtained data indicate that both the direct cross-linking anti-CD3-anti-CD33 bsAb and the modular cell targeting system hold great potential as an adjuvant cancer immunotherapy for the elimination of MRD in AML-patients.
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Improved Killing of AML Blasts By Dual-Targeting of CD123 and CD33 Via Unitarg a Novel Antibody-Based Modular T Cell Retargeting System
Claudia Arndt,Claudia Arndt,Anja Feldmann,Anja Feldmann,Stefanie Koristka,Stefanie Koristka,Marc Cartellieri,Malte von Bonin,Armin Ehninger,Martin Bornhäuser,Gerhard Ehninger,Michael Bachmann +11 more
TL;DR: A novel antibody-based modular platform (UniTARG) that can be rapidly and easily adapted for redirection of T cells to any TAA in both a bsAb or CAR related manner and that lysis of CD123+ CD33+ AML blasts can be considerably improved in comparison to the mono-specific strategy.
Journal ArticleDOI
And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling
Nicole Berndt,Claudia C. Bippes,Irene Michalk,Tabea Bartsch,Claudia Arndt,Edinson Puentes-Cala,Javier Andrés Soto,Javier Andrés Soto,Liliana R. Loureiro,Alexandra Kegler,Dominik Bachmann,Joanne K Gross,Tim Gross,Biji T. Kurien,R. Hal Scofield,A. Darise Farris,Judith A. James,Ralf Bergmann,Ralf Bergmann,Marc Schmitz,Anja Feldmann,Michael Bachmann,Michael Bachmann +22 more
TL;DR: In this paper, it was shown that ligands of toll-like receptors lead to a redox-dependent shuttling of La protein and showed that translocation of La proteins can be triggered in a ligand/receptor-dependent manner under physiological conditions.
Quo vadis Open-IX? Trying to boost public peering in the US
TL;DR: In this article, the authors examine the cast of Internet stakeholders that are bound to play a critical role in determining the fate of the Open-IX effort and discuss some of the economic arguments that will ultimately determine whether or not the currently pursued strategy by OIX will succeed in achieving the main OIX-articulated goal of a more level playing field for private and public peering in the US such that the actual demand and supply for the different peering opportunities will be reflected in the cost structure.