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Anna K. McGow
Researcher at Brigham and Women's Hospital
Publications - 1
Citations - 125
Anna K. McGow is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Tumor progression & Cancer-Associated Fibroblasts. The author has an hindex of 1, co-authored 1 publications receiving 49 citations.
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Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer.
Lisa M. Becker,Joyce T. O’Connell,Annie P. Vo,Margo P. Cain,Désirée Tampe,Lauren Bizarro,Lauren Bizarro,Hikaru Sugimoto,Hikaru Sugimoto,Anna K. McGow,John M. Asara,John M. Asara,Sara Lovisa,Kathleen M. McAndrews,Rafal Zielinski,Philip L. Lorenzi,Michael Zeisberg,Sughra Raza,Valerie S. LeBleu,Valerie S. LeBleu,Valerie S. LeBleu,Raghu Kalluri +21 more
TL;DR: It is demonstrated that CAFs exhibit a metabolic shift toward lactate and pyruvate production and fuel biosynthetic pathways of cancer cells, and their breast cancer-promoting phenotype is partly mediated by oxygen-dependent epigenetic modifications.