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Anna Rita Migliaccio
Researcher at University of Bologna
Publications - 288
Citations - 20175
Anna Rita Migliaccio is an academic researcher from University of Bologna. The author has contributed to research in topics: Haematopoiesis & Progenitor cell. The author has an hindex of 56, co-authored 276 publications receiving 19272 citations. Previous affiliations of Anna Rita Migliaccio include Mount Sinai Hospital & New York Blood Center.
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Non-Cancer Uses of Histone Deacetylase Inhibitors: Effects on Infectious Diseases and β-Hemoglobinopathies+
Dante Rotili,Giovanna Simonetti,Andrea Savarino,Anna Teresa Palamara,Anna Rita Migliaccio,Antonello Mai +5 more
TL;DR: Among the many agents capable to perform post-natal reactivation of fetal hemoglobin production, HDACi for their capacity to de-repress gamma-globin gene expression in adult red cell, are presently considered promising molecules for personalized therapy of beta-hemoglobinopathies.
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Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1low mouse model of the disease
Anna Rita Migliaccio,Fabrizio Martelli,Maria Verrucci,Giovanni Migliaccio,Alessandro M. Vannucchi,Hongyu Ni,Mingjiang Xu,Yi Jiang,Betty Nakamoto,Thalia Papayannopoulou,Ronald Hoffman +10 more
TL;DR: It is suggested that abnormalities in the SDF-1/CXCR4 axis are observed in PMF patients and in the Gata1 low mice model of myelofibrosis and contribute to the increased stem/progenitor cell trafficking observed in this mouse model as well as patients with PMF.
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Hematopoietic progenitors in cyclic neutropenia: effect of granulocyte colony-stimulating factor in vivo.
TL;DR: Results indicate that treatment with G-CSF not only ameliorated the neutropenia, but also increased the amplitude and the frequency of oscillation of circulating progenitor cell numbers, consistent with the hypothesis that G- CSF therapy affects the proliferation of the hematopoietic stem cell.
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Megakaryocyte Contribution to Bone Marrow Fibrosis: many Arrows in the Quiver.
Alessandro Malara,Vittorio Abbonante,Maria Zingariello,Anna Rita Migliaccio,Alessandra Balduini,Alessandra Balduini +5 more
TL;DR: The role and the altered secretion of megakaryocyte-derived soluble factors, enzymes and extracellular matrices that are known to induce bone marrow fibrosis are discussed.
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Evidence for direct action of human biosynthetic (recombinant) GM-CSF on erythroid progenitors in serum-free culture.
TL;DR: Results provide evidence that GM- CSF acts directly on early erythroid progenitors and suggest that both Ep and GM-CSF are necessary to start the differentiation process.