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Anne P. Werner
Researcher at National Institutes of Health
Publications - 22
Citations - 2524
Anne P. Werner is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Antibody & Vaccination. The author has an hindex of 8, co-authored 18 publications receiving 1134 citations.
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Journal ArticleDOI
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates.
Kizzmekia S. Corbett,Barbara J. Flynn,Kathryn E. Foulds,Joseph R. Francica,Seyhan Boyoglu-Barnum,Anne P. Werner,Britta Flach,Sarah O’Connell,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Hanne Leth Andersen,David R. Martinez,Amy T. Noe,Naomi Douek,Mitzi M. Donaldson,Nadesh N Nji,Gabriela S. Alvarado,Darin K. Edwards,Dillon R. Flebbe,Evan Lamb,Nicole A. Doria-Rose,Bob C. Lin,Mark K. Louder,Sijy O'Dell,Stephen D. Schmidt,Emily Phung,Lauren A. Chang,Christina Yap,John-Paul Todd,Laurent Pessaint,Alex Van Ry,Shanai Browne,Jack Greenhouse,Tammy Putman-Taylor,Amanda Strasbaugh,Tracey-Ann Campbell,Anthony Cook,Alan Dodson,Katelyn Steingrebe,Wei Shi,Yi Zhang,Olubukola M. Abiona,Lingshu Wang,Amarendra Pegu,Eun Sung Yang,Kwanyee Leung,Tongqing Zhou,I-Ting Teng,Alicia T. Widge,Ingelise J. Gordon,Laura Novik,Rebecca A. Gillespie,Rebecca J. Loomis,Juan I. Moliva,Guillaume Stewart-Jones,Sunny Himansu,Wing-Pui Kong,Martha Nason,Kaitlyn M. Morabito,Tracy J. Ruckwardt,Julie E. Ledgerwood,Martin R. Gaudinski,Peter D. Kwong,John R. Mascola,Andrea Carfi,Mark G. Lewis,Ralph S. Baric,Adrian B. McDermott,Ian N. Moore,Nancy J. Sullivan,Mario Roederer,Robert A. Seder,Barney S. Graham +73 more
TL;DR: Vaccination of nonhuman primates with mRNA-1273 induced robust SARS-CoV-2 neutralizing activity, rapid protection in the upper and lower airways, and no pathologic changes in the lung.
Posted ContentDOI
mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants
Kai Wu,Anne P. Werner,Juan I. Moliva,Matthew A. Koch,Angela Choi,Guillaume Stewart-Jones,Hamilton Bennett,Seyhan Boyoglu-Barnum,Wei Shi,Barney S. Graham,Andrea Carfi,Kizzmekia S. Corbett,Robert A. Seder,Darin K. Edwards +13 more
TL;DR: In this paper, the authors assessed the neutralizing capacity of sera from human subjects or non-human primates (NHPs) that received mRNA-1273 vaccination, using two orthogonal VSV and lentivirus PsVN assays expressing spike variants of 20E (EU1), 20A.7, and B.1.351.
Journal ArticleDOI
Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine.
Kai Wu,Anne P. Werner,Matthew A. Koch,Angela Choi,Elisabeth Narayanan,Guillaume Stewart-Jones,Tonya M. Colpitts,Hamilton Bennett,Seyhan Boyoglu-Barnum,Wei Shi,Juan I. Moliva,Nancy J. Sullivan,Barney S. Graham,Andrea Carfi,Kizzmekia S. Corbett,Robert A. Seder,Darin K. Edwards +16 more
TL;DR: In this paper, the mRNA-1273 vaccine was shown to neutralize the P.1.1 lineage, the B. 1.7 lineage, and B. 7 lineage plus t
Journal ArticleDOI
Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates.
Kizzmekia S. Corbett,Martha Nason,Britta Flach,Matthew Gagne,Sarah O’Connell,Timothy S. Johnston,Shruti N. Shah,Venkata Viswanadh Edara,Katharine Floyd,Lilin Lai,Charlene McDanal,Joseph R. Francica,Barbara J. Flynn,Kai Wu,Angela Choi,Matthew A. Koch,Olubukola M. Abiona,Anne P. Werner,Juan I. Moliva,Shayne F. Andrew,Mitzi M. Donaldson,Jonathan Fintzi,Dillon R. Flebbe,Evan Lamb,Amy T. Noe,Saule T. Nurmukhambetova,Samantha J. Provost,Anthony L. Cook,Alan Dodson,Andrew Faudree,Jack Greenhouse,Swagata Kar,Laurent Pessaint,Maciel Porto,Katelyn Steingrebe,Daniel Valentin,Serge Zouantcha,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Renee van de Wetering,Seyhan Boyoglu-Barnum,Kwanyee Leung,Wei Shi,Eun Sung Yang,Yi Zhang,John Paul Todd,Lingshu Wang,Gabriela S. Alvarado,Hanne Leth Andersen,Kathryn E. Foulds,Darin K. Edwards,John R. Mascola,Ian N. Moore,Mark G. Lewis,Andrea Carfi,David C. Montefiori,Mehul S. Suthar,Adrian B. McDermott,Mario Roederer,Nancy J. Sullivan,Daniel C. Douek,Barney S. Graham,Robert A. Seder +63 more
TL;DR: In this paper, nonhuman primates (NHPs) received either no vaccine or doses ranging from 0.3 to 100 μg of the mRNA-12 protein, which can be used as surrogate endpoints for vaccine efficacy.
Journal ArticleDOI
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
Matthew Gagne,Juan I. Moliva,Kathryn E. Foulds,Shayne Andrew,Barbara J. Flynn,Anne P. Werner,Danielle A Wagner,I-Ting Teng,Bob C. Lin,Christopher Brooks Moore,Nazaire Jean-Baptiste,Robin E. Carroll,Stephanie L. Foster,Mit Patel,Madison Ellis,Venkata Viswanadh Edara,Nahara Vargas Maldonado,Mahnaz Minai,Lauren McCormick,Christopher Cole Honeycutt,Bianca M. Nagata,Kevin W. Bock,Caitlyn N. M. Dulan,Jamilet Cordon,Dillon R. Flebbe,John Paul Todd,Elizabeth McCarthy,Laurent Pessaint,Alex Van Ry,Brandon Narvaez,Daniel Valentin,Anthony Cook,Alan Dodson,Katelyn Steingrebe,Saule Nurmukhambetova,Sucheta Godbole,Amy R. Henry,Farida Laboune,Jesmine Roberts-Torres,Cynthia G. Lorang,Shivani G. Amin,Jessica F. Trost,M. Naisan,Manjula Basappa,J. B. Willis,Lingshu Wang,Wei Shi,Nicole A. Doria-Rose,Yi Zhang,Eun Sung Yang,Kwanyee Leung,Sijy O'Dell,R. Schmidt,Adam S. Olia,Cuiping Liu,Darcy R. Harris,Gwo-Yu Chuang,Guillaume Stewart-Jones,Isabella Renzi,Yen-Ting Lai,Agata Malinowski,Kai Wu,John R. Mascola,Andrea Carfi,Peter D. Kwong,Darin K. Edwards,Mark A. Lewis,Hanne Andersen,Kizzmekia S. Corbett,Martha Nason,Adrian B. McDermott,Mehul S. Suthar,Ian N. Moore,Mario Roederer,Nancy J. Sullivan,Daniel C. Douek,Robert A. Seder +76 more
TL;DR: In this article , the authors showed that boosting with Omicron-matched vaccines would enhance protection, but it is unclear whether boosting with omicron matched vaccines would improve protection.