J
Jonathan Fintzi
Researcher at National Institutes of Health
Publications - 27
Citations - 712
Jonathan Fintzi is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Vaccine efficacy & Vaccination. The author has an hindex of 8, co-authored 24 publications receiving 291 citations. Previous affiliations of Jonathan Fintzi include University of Washington.
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Journal ArticleDOI
An immune-based biomarker signature is associated with mortality in COVID-19 patients.
Michael S. Abers,Ottavia M. Delmonte,Emily Ricotta,Jonathan Fintzi,Danielle Fink,Adriana Almeida de Jesus,Kol A. Zarember,Sara Alehashemi,Vasileios Oikonomou,Jigar V. Desai,Scott W. Canna,Bita Shakoory,Kerry Dobbs,Luisa Imberti,Alessandra Sottini,Eugenia Quiros-Roldan,Francesco Castelli,Camillo Rossi,Duilio Brugnoni,Andrea Biondi,Laura Rachele Bettini,Mariella D'Angiò,Paolo Bonfanti,Riccardo Castagnoli,Daniela Montagna,Amelia Licari,Gian Luigi Marseglia,Emily F. Gliniewicz,Elana Shaw,Dana Kahle,Andre Rastegar,Michael Stack,Katherine Myint-Hpu,Susan L Levinson,Mark J. DiNubile,Daniel W. Chertow,Peter D. Burbelo,Jeffrey I. Cohen,Katherine R. Calvo,John S. Tsang,Helen C. Su,John I. Gallin,Douglas B. Kuhns,Raphaela Goldbach-Mansky,Michail S. Lionakis,Luigi D. Notarangelo +45 more
TL;DR: Levels of sST2, sTNFRSF1A, IL-10, and IL-15 were consistently higher throughout the hospitalization in patients who died versus those who recovered, suggesting that these biomarkers may provide an early warning of eventual disease outcome.
Journal ArticleDOI
Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates.
Kizzmekia S. Corbett,Martha Nason,Britta Flach,Matthew Gagne,Sarah O’Connell,Timothy S. Johnston,Shruti N. Shah,Venkata Viswanadh Edara,Katharine Floyd,Lilin Lai,Charlene McDanal,Joseph R. Francica,Barbara J. Flynn,Kai Wu,Angela Choi,Matthew A. Koch,Olubukola M. Abiona,Anne P. Werner,Juan I. Moliva,Shayne F. Andrew,Mitzi M. Donaldson,Jonathan Fintzi,Dillon R. Flebbe,Evan Lamb,Amy T. Noe,Saule T. Nurmukhambetova,Samantha J. Provost,Anthony L. Cook,Alan Dodson,Andrew Faudree,Jack Greenhouse,Swagata Kar,Laurent Pessaint,Maciel Porto,Katelyn Steingrebe,Daniel Valentin,Serge Zouantcha,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Renee van de Wetering,Seyhan Boyoglu-Barnum,Kwanyee Leung,Wei Shi,Eun Sung Yang,Yi Zhang,John Paul Todd,Lingshu Wang,Gabriela S. Alvarado,Hanne Leth Andersen,Kathryn E. Foulds,Darin K. Edwards,John R. Mascola,Ian N. Moore,Mark G. Lewis,Andrea Carfi,David C. Montefiori,Mehul S. Suthar,Adrian B. McDermott,Mario Roederer,Nancy J. Sullivan,Daniel C. Douek,Barney S. Graham,Robert A. Seder +63 more
TL;DR: In this paper, nonhuman primates (NHPs) received either no vaccine or doses ranging from 0.3 to 100 μg of the mRNA-12 protein, which can be used as surrogate endpoints for vaccine efficacy.
Journal ArticleDOI
Ambient air quality measurements from a continuously moving mobile platform: Estimation of area-wide, fuel-based, mobile source emission factors using absolute principal component scores
Timothy V. Larson,Timothy Gould,Erin A. Riley,Elena Austin,Jonathan Fintzi,Lianne Sheppard,Michael G. Yost,Christopher D. Simpson +7 more
TL;DR: The absolute principal component scores (APCS) receptor model was applied to on-road, background-adjusted measurements of NOx, CO, CO2, black carbon, and particle number obtained from a continuously moving platform deployed over nine afternoon sampling periods in Seattle, WA and found two Varimax-rotated principal component features described 75% of the overall variance of the observations.
Posted ContentDOI
Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates
Kizzmekia S. Corbett,Martha Nason,Britta Flach,Matthew Gagne,Timothy S. Johnston,Shruti N. Shah,Venkata Vishwanadh Edara,Katharine Floyd,Lilin Lai,Charlene McDanal,Joseph R. Francica,Barbara J. Flynn,Kai Wu,Angela Choi,Matthew A. Koch,Olubukola M. Abiona,Anne P. Werner,Gabriela S. Alvarado,Shayne F. Andrew,Mitzi M. Donaldson,Jonathan Fintzi,Dillon R. Flebbe,Evan Lamb,Amy T. Noe,Saule T. Nurmukhambetova,Samantha J. Provost,Anthony L. Cook,Alan Dodson,Andrew Faudree,Jack Greenhouse,Swagata Kar,Laurent Pessaint,Maciel Porto,Katelyn Steingrebe,Daniel Valentin,Serge Zouantcha,Kevin W. Bock,Mahnaz Minai,Bianca M. Nagata,Juan I. Moliva,Renee van de Wetering,Seyhan Boyoglu-Barnum,Kwanyee Leung,Wei Shi,Eun Sung Yang,Yi Zhang,John-Paul Todd,Lingshu Wang,Hanne Leth Andersen,Kathryn E. Foulds,Darin K. Edwards,John R. Mascola,Ian N. Moore,Mark G. Lewis,Andrea Carfi,David C. Montefiori,Mehul S. Suthar,Adrian B. McDermott,Nancy J. Sullivan,Mario Roederer,Daniel C. Douek,Barney S. Graham,Robert A. Seder +62 more
TL;DR: In this article, a nonhuman primate (NHP) model of SARS-CoV-2 infection replicates key features of human infection and may be used to define immune correlates of protection following vaccination.
Journal ArticleDOI
Multi-pollutant mobile platform measurements of air pollutants adjacent to a major roadway.
Erin A. Riley,Lyndsey Banks,Jonathan Fintzi,Timothy Gould,Kris Hartin,LaNae Schaal,Mark Davey,Lianne Sheppard,Timothy V. Larson,Michael G. Yost,Christopher D. Simpson +10 more
TL;DR: The raster sampling scheme combined with spatial and temporal measurement alignment provide a measure of variability in the near roadway concentrations, and allow us to use a principal component analysis to identify multi-pollutant features and analyze their roadway influences.